Clinical trials: Lymphedema
Pelvic Floor Disorder, Female Pelvic Floor Dysfunction
Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment
Late side-effects following gynecological cancer are predominantly symptoms from the pelvic region originating from the bowels, urinary tract, lymphatic system, genitals and musculoskeletal system.
- Conditions
- Pelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary Incontinence
- Trial name
- NCT06786091
- Testing
- Pelvic floor muscle training rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 25 people
- Sponsor
- St. Olavs Hospital
Axillary Web Syndrome, Breast Cancer
Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes
Axillary web syndrome (AWS), sometimes called "cording," is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled.
- Conditions
- Axillary Web Syndrome, Breast Cancer, Breast Cancer Lymphedema, Postoperative Complications
- Trial name
- NCT07780240
- Testing
- Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya City Hospital
Primary Lymphedema, Secondary Lymphedema
Biological Profile of Primary and Secondary Lymphedema: Inflammatory, Endothelial, Metabolic, Lymphatic, and Fibrotic Markers
This observational, cross-sectional study aims to characterize the biological profile of primary and secondary lymphedema by investigating five interconnected biological domains: T helper 2 (Th2)-related inflammation, endothelial…
- Trial name
- LYMPH5 (NCT07770399)
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Breast Cancer, Breast Lymphedema
Efficacy of Kinesio Taping Versus Compression Therapy on Breast Lymphedema Induced by Radiotherapy After Breast-Conserving Surgery
Breast cancer patients often develop breast lymphedema after breast-conserving surgery and radiotherapy, causing swelling, pain, and heaviness that affect quality of life.
- Trial name
- NCT07767305
- Testing
- Routine Care, Kinesio Taping, Compression Therapy
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Tangshan People's Hospital
Lymphedema, Breast Cancer, Lymphedema
LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy
Lymphedema is a chronic, progressive, and debilitating condition that occurs with disruption or obstruction of the lymphatic system, which commonly occurs a result of breast cancer therapy.
- Trial name
- NCT05366699
- Testing
- axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA), Axillary lymphadenetomy alone, axillary lymphadenectomy with soft tissue reinforcement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Lymphedema, Breast Cancer
Investigation of the Effectiveness of Progressive Resistance Exercise Training in the Management of Lymphedema.
This study aims to investigate the effect of progressive resistance exercise training on the clinical findings and functional outcomes of lymphedema in individuals who develop upper extremity lymphedema after breast cancer…
- Trial name
- NCT07448467
- Testing
- control, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uskudar University
Lower Extremity Lymphedema
Evaluate Advanced Pneumatic Compression Device With Revised Compression Programming for Lymphedema Treatment
The goal of this pilot study is to learn if a revised method of compression improves lymphatic function compared to the current method of compression.
- Trial name
- NCT07613931
- Testing
- Advanced pneumatic compression device (APCD), Advanced pneumatic compression device (APCD) with revised compression programming, Indocyanine Green (IC-Green)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tactile Medical
Breast Cancer, Axillary Nodal Disease
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or…
- Conditions
- Breast Cancer, Axillary Nodal Disease, Female Breast Cancer, Axilla; Breast
- Trial name
- NCT06092892
- Testing
- Breast Surgery (BCS or mastectomy) with TAD/SNB, Adjuvant Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alice Chung
Postmastectomy Lymphedema
Effect of CKC and WS Exercises on Postural Stability in Unilateral Post Mastectomy Lymphedema
Post-mastectomy lymphedema is one of the most common chronic complications that significantly impacts patients' quality of life following breast cancer surgery.
- Trial name
- NCT06977620
- Testing
- Closed kinetic chain exercises, Weight shifting exercises, Complete Decongestive Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Balance in Lymphedema, Lymphedema
Relationship Between Balance and Body Awareness in Lymphedema Patients
Lymphedema (LE) is a chronic condition caused by the accumulation of protein-rich fluid in the subcutaneous tissue as a result of insufficiency of the lymphatic system .
- Trial name
- NCT07744906
- Testing
- mini best balance quaestionare, Evaluation of body awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Breast Cancer and Rehabilitation
Effect of Preoperative Rehabilitation Exercise on Improving Postoperative Lymphedema, Quality of Life and Care Needs in Patients With Breast Cancer Surgery
Breast cancer is one of the most common cancers among women worldwide, with surgery being a primary treatment. However, surgical tumor resection combined with lymph node dissection often leads to upper extremity lymphedema as a…
- Trial name
- NCT07743294
- Testing
- Preoperative Upper Limb Rehabilitation Exercise, Standard Nursing Care and Education
- Where
- 2 sites in Taiwan
- Volunteers
- 105 people
- Sponsor
- National Taiwan University Hospital
Fibrosis Syndrome, Lymphedema
Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)
To find out if adding medication can help treat or prevent lymphedema and/or fibrosis related to radiation therapy, in survivors of head and neck cancer.
- Conditions
- Fibrosis Syndrome, Lymphedema, Head &Amp; Neck Cancer, Fibrosis
- Trial name
- NCT06912763
- Testing
- Pravastatin (drug), Pentoxifylline, ketoprofen
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- M.D. Anderson Cancer Center
Lower Extremity Lymphedema
Aerobic Exercise Effects in Lower Extremity Lymphedema
Lower extremity lymphedema negatively affects patients' functional status, quality of life, and activities of daily living. Complete decongestive therapy (CDT) is considered the gold-standard conservative treatment for patients…
- Trial name
- NCT07726277
- Testing
- aerobic exercise program, complet decongestive therapy
- Volunteers
- 50 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen
Lymphedema Arm
Mobile Self-Management Training for Lymphedema Prevention
Breast cancer is the most common cancer among women in the world and in our country and affects women negatively in many ways. Depending on the treatment, patients experience serious problems.
- Trial name
- lymphedema (NCT07043140)
- Testing
- mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Inonu University
Breast Cancer, Pain
Advancing Patient Care for Lymphatic Pain and Lymphedema
Lymphatic pain refers to various pain sensations (e.g., pain, aching, soreness, tenderness, burning, stabbing) following breast cancer treatment.
- Conditions
- Breast Cancer, Pain, Lymphedema Arm
- Trial name
- NCT07701018
- Testing
- The-Optimal-Lymph-Flow
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Missouri, Kansas City
Lymphedema, Lymphedema Arm
Screening For BCRL In Targeted Therapy For Breast Cancer
This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT05142800
- Testing
- Perometer, SOZO device
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Breast Cancer Treatment Related Lymphedema
Early Intervention
This research study is a Pilot Study examining the use of a compression sleeve with embedded sensor to prevent lymphedema.
- Trial name
- NCT05326165
- Testing
- Juzo Compression Sleeve and Glove, Compression Sleeve Sensor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Lymphedema, Lymphedema of Face
Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during open lymphatic reconstruction in the head and neck.
- Conditions
- Lymphedema, Lymphedema of Face, Internal Lymphedema, External Lymphedema
- Trial name
- CLEAR (NCT07311876)
- Testing
- Symani Surgical System
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Lymphedema, Lymphedema Lower Extremity
Aerobic Training in Lower Extremity Lymphedema
This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity…
- Trial name
- NCT07414615
- Testing
- Complex Decongestive Physiotherapy (CDP), Aerobic Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University