Clinical trials: Lymphedema of Upper Limb
Breast Cancer, Lymphedema Arm
Impact of the ARM Technique on the Prevention of Lymphedema After Axillary Lymphadenectomy: A Multicenter Randomized Clinical Trial
To evaluate the reduction of secondary lymphedema following axillary lymphadenectomy by incorporating the ARM technique during the procedure, without negatively impacting patient prognosis.
- Trial name
- ARM-LIFE (NCT07515300)
- Testing
- Axillary Reverse Mapping
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari de Bellvitge
Lymphedema, Lymphedema of Upper Arm
A Multi-center Randomized Control Cross-over Study to Evaluate the Safety and Effectiveness of the Dayspring Active Wearable Compression Device vs. an Advanced Pneumatic Compression Device for Treating Breast Cancer Related Lymphedema
To evaluate the Dayspring Active Wearable Compression Device in contrast to an advanced pneumatic compression device (APCD)
- Conditions
- Lymphedema, Lymphedema of Upper Arm, Lymphedema, Breast Cancer
- Trial name
- NILE (NCT04908254)
- Testing
- Crossover Device (PCD or Dayspring - alternate to first group)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Koya Medical, Inc.
Lymphedema Arm, Lymphedema; Surgical
Assessment of Muscle Strength and Volume Changes in Patients With Breast Cancer- Related Lymphedema
This study aims to find whether complete decongestive therapy used in breast cancer-related lymphedema has an effect on muscle strength in the affected arm, while assessing the efficacy of the therapy itself.
- Trial name
- NCT03945838
- Testing
- Complete Decongestion Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ege University
Lymphedema of Leg
Hydrophobic Tubes for the Treament of Lower and Upper Limb Lymphedema
Lymphedema is a chronic condition causing fluid buildup in affected limbs. Traditional treatments often fall short, but subcutaneous implantation of hydrophobic silicone tubes shows promise, creating artificial drainage pathways.
- Trial name
- NCT05970068
- Testing
- implantation of hydrophobic tubes for edema fluid drainage, Best Medical Treatment
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Universidade do Porto
Lymphedema Arm, Lymphedema of Leg
LymphAssistTM at Home (LAAH)
Lymphoedema is a life-long condition causing long-term swelling affecting people physically, mentally and socially. Daily self-management covers four main areas (skin care, activity / movement, compression and massage / light…
- Trial name
- LAAH (NCT05456568)
- Testing
- LymphAssistTM Professional
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Swansea Bay University Health Board
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Lymphedema, Lymphedema Arm
The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
This study assesses the performance of robot-assisted microsurgery. Lymphaticovenous anastomosis (LVA) is the most difficult procedure in microsurgery at this moment.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT06532955
- Testing
- Lymphaticovenous anastomosis using Microsure Motion Stabilizer, Lymphaticovenous anastomosis (manual)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Head and Neck Cancer
Home-Based Photo-Biomodulation for Management of Lymphoedema and Radiation Fibrosis in Patients After Head and Neck Cancer: A Single-Arm Feasibility Trial
This feasibility trial will test the use of photo-biomodulation (PBM) therapy, predominantly self-delivered in the patient's home for 12-weeks, following completion of radiotherapy treatment for head and neck cancer.
- Trial name
- HOME-PBM (NCT07139782)
- Testing
- Riancorp LTU-904 Laser and Handycure® (Medical Quant)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Lymphedema, Lymphedema Arm
Screening For BCRL In Targeted Therapy For Breast Cancer
This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT05142800
- Testing
- Perometer, SOZO device
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Surgery, Transcutaneous Electric Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Breast Surgery
The aim of this randomized controlled trial was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on postoperative pain, lymphedema development, shoulder range of motion, and quality of life in women…
- Trial name
- NCT06973265
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Seda Akutay
Lymphedema Arm
Efficacy of Home-based Treatment for Breast Cancer-related Lymphedema
The goal of this clinical trials is to explore the effectiveness of home-based iymphedema treatment and the differences between the home-based and outpatient treatment.
- Trial name
- NCT06783543
- Testing
- Comprehensive detumescence treatment with education video, Comprehensive detumescence treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Lymphedema
Effects of Inspiratory Muscle Training on Lymphedema
The aim of this study is to examine the effect of inspiratory muscle training on lymphedema volume, subcutaneous tissue thickness, upper extremity functionality and sleep quality in the treatment of upper extremity lymphedema.
- Trial name
- NCT06521268
- Testing
- Inspiratory muscle training, Decongestive treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Biruni University
Lymphedema, Secondary, Lymphedema of Upper Limb
Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device
This study will be a 4 to 6 week randomized, controlled, assessor blinded, trial comparing a negative pressure massage device (intervention group), to the standard manual lymph drainage massage (control group), in breast cancer…
- Trial name
- NCT03252145
- Testing
- PhysioTouch, Manual Lymph Drainage (MLD)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
Breast Cancer-Related Lymphedema, Breast Cancer
Pedicled Lateral Chest Wall Lymph-Adipofascial Flap to Prevent Arm Lymphedema After Breast Cancer Surgery
Breast cancer surgery that includes removal of lymph nodes from the armpit (axillary lymph node dissection) can disrupt normal lymphatic drainage and may lead to arm swelling, known as lymphedema.
- Conditions
- Breast Cancer-Related Lymphedema, Breast Cancer, Postoperative Complications
- Trial name
- LAF-ALND (NCT07415200)
- Testing
- Pedicled Lateral Chest Wall Lymph-Adipofascial Flap Axillary Reconstruction
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lymph Node Cancer Metastatic
Axillary Reverse Mapping in Breast Cancer
The axillary mapping reverse (ARM) consists in differentiating the upper limb lymph nodes from the breast ones in order to preserve them and reduce the possibility of lymphedema.
- Trial name
- ARM (NCT05040685)
- Testing
- Axillary mapping reverse
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Lymphedema
Lymphedema Upper Limb of Breast Cancer Through Muscle Strengthening Associated With Complex Physical Therapy
The stage and lymphedema size can be detrimental to the quality of life and health of women, because the increase in circumference and member of the weight causes limitations in activities.
- Trial name
- LTP (NCT02574780)
- Testing
- complex physical therapy, Evaluate treatment of lymphedema, with in the quality of life and depression
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Federal University of São Paulo
Lymphedema Arm, Lymphedema Due to Radiation
Effectiveness of a Therapeutic Exercise Program With Specific Upper Limb Exercises to Reduce Lymphedema and Neuropathy in Breast Cancer Patients: A Pre-post Study (LYNMA)
This study aims to evaluate the effectiveness of a therapeutic exercise program designed specifically for women with breast cancer.
- Conditions
- Lymphedema Arm, Lymphedema Due to Radiation, Lymphedema, Breast Cancer, Peripheral Neuropathy Due to Chemotherapy
- Trial name
- LYNMA (NCT07170631)
- Testing
- Therapeutic exercise
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Breast Cancer Lymphedema
Radial Shock Wave Treatment Alongside Decongestive Care for Arm Swelling After Breast Cancer
Arm swelling can persist after breast cancer treatment and may interfere with comfort, movement, and everyday activities. Decongestive care combines several approaches to manage this swelling.
- Trial name
- NCT07862296
- Testing
- Complex decongestive therapy, Radial extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Selcuk University
Lymphedema
Pycnogenol for the Treatment of Lymphedema
The objectives of this study are to evaluate the effectiveness of Pycnogenol (French maritime pine bark extract) for arm lymphedema in women following treatment for breast cancer, to evaluate the accuracy and sensitivity of…
- Trial name
- NCT00214032
- Testing
- Pycnogenol
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Lymphedema of Upper Limb
Body Awareness and Functionality in Lymphedema
To determine whether body awareness and upper extremity functionality are affected in patients with or without lymphedema development after breast cancer surgery in comparison with individuals without a history of cancer.
- Trial name
- NCT06036173
- Testing
- diagnosis of lymphedema, breast cancer surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Selcuk University