Clinical trials: Lymphocytes
Preeclampsia, Eclampsia
The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the…
- Trial name
- NCT01856387
- Testing
- high neutrophil to lymphocyte ratio, normal neutrophil-to Lymphocyte ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Brain and Central Nervous System Tumors, Leukemia
Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial
RATIONALE: Gathering information about why patients or their guardians agree or decline to participate in the optional pharmacokinetic portion of a phase I treatment study may help doctors plan clinical trials in the future.
- Conditions
- Brain and Central Nervous System Tumors, Leukemia, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00890435
- Testing
- questionnaire administration, psychosocial assessment and care
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Prostate Cancer
Periperal Blood Lymphocytes During Prostate RT
Right now it is not possible to predict which patients are going to react more to RT. Many things could affect patient's response to radiation.
- Trial name
- NCT01899391
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Adenomyosis, Leiomyoma
New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma
Both pelvic masses and preoperative diagnosis of them have still continued as an important investigation subject. It is important to discriminate the diagnoses of leiomyoma and adenomyosis before operation especially among…
- Conditions
- Adenomyosis, Leiomyoma, Inflammation
- Trial name
- NCT02997787
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
There Are no Conditions Under Study. Healthy Volunteers
Eccentric Cycling Exercise With Assistive Devices on Mitochondrial Metabolism in T Lymphocyte
Eccentric cycling exercise can be a promising modality fwith lower respiratory demands and higher power output. Assistive devices like neuromuscular electrical stimulation (NMES) and compressive garment (CG) accelerates muscle…
- Trial name
- NCT06905964
- Testing
- Eccentric cycling exercise (ECC), Eccentric cycling exercise with assistive devices (ECA)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer
The Role of Mucosal Associated Invariant t Lymphocytes in Breast Cancer
Evaluation of MAIT cells in patient recently diagnosed as cancer breast and its correlation with clinical outcome. Mucosal Associated Invariant T cells are a population of unconventional T cells which are enriched in mucosal…
- Trial name
- NCT07000396
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Safety and Immune Enhancing Effects of Acute Dosing of COLD-fX in Healthy Adults
Subjects will be asked to participate in a four day research study of the immune system effects and safety of short-term acute dosing of Cold-fX.
- Trial name
- NCT00435968
- Testing
- CVT E002 (Cold-fX)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CV Technologies
COVID-19 Disease
Role of Lymphocyte Subsets and Laboratory Measurements in COVID-19 Disease
To investigate the predictive role of lymphocyte subsets and other laboratory measurements in adult patients with COVID-19.This was a single center, retrospective study that involved adult patients with confirmed diagnosis of…
- Trial name
- NCT04779359
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Shanghai Public Health Clinical Center
Biotin Deficiency
Biotin Status in Pregnancy
The purpose of this study is to estimate the number of pregnant women who, during pregnancy, have low levels of the vitamin biotin.
- Trial name
- NCT00894920
- Testing
- biotin
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy Volunteers, HIV
Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies
This study will collect blood plasma and white blood cells from individuals using a procedure called apheresis. Apheresis is a method of collecting larger quantities of certain blood components that can safely be collected…
- Trial name
- NCT00114647
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vitamin A Deficiency
Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function
Vitamin A supplementation at birth may increase survival of infants through one year of age by reducing mortality from infectious diseases, though current studies are not conclusive on this point.
- Trial name
- NCT01583972
- Testing
- retinyl palmitate
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Alcoholic Liver Disease, Chronic Hepatitis C Virus
Study of T Cell Phenotype Activation Pathway in Human Alcoholic Liver Disease
Alcoholic liver disease is characterized by circulating T cell activation and liver T cell infiltration but their phenotype is poorly studied.
- Trial name
- NCT00610597
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Recurrence, Metastasis
The Clinical Relevance of Immune Cells and CTC in HNSCC Patients
Head and neck squamous cell carcinomas (HNSCCs) are mainly caused by tobacco, alcohol consumption and betel nut chewing and the sixth most common cancer in the world.
- Conditions
- Recurrence, Metastasis, Death
- Trial name
- NCT02420600
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Graft vs Host Disease, Hematologic Neoplasm
Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease
Blood contains different kinds of cells, white blood cells, red blood cells, and platelets. In order to treat certain diseases, specific cell types can be removed from blood and transplanted into patients.
- Trial name
- NCT00001872
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV Infections, Healthy
Prediction and Testing of Antigenic Sites of the AIDS Virus, HTLV-III Recognized by T Lymphocytes for the Development of Synthetic Vaccines
Subjects are healthy adult volunteers either at high risk for HIV infection or already known to be seropositive, who will donate blood for in vitro tests of T-cell function and in vitro responses to synthetic peptides…
- Trial name
- NCT00001210
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Juvenile Idiopathic Arthritis
Analysis of Peripheral Blood Lymphocytes in Patients With Juvenile Idiopathic Arthritis With Respect to Disease Subtypes and Therapy
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children. JIA is an umbrella term defining several forms of chronic arthritis with an onset before the age of 16 years, persisting for more than…
- Trial name
- NCT06413563
- Testing
- Complete blood count
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sohag University
Nephrotic Syndrome, Infections
The Predictive Value of Dynamic Changes of CD4+T Lymphocytes in Primary Nephrotic Syndrome With Infection
The goal of this observational study is to test whether the dynamic changes of CD4+T lymphocytes can predict infections in patients with primary nephrotic syndrome .
- Conditions
- Nephrotic Syndrome, Infections, Lymphocyte
- Trial name
- NCT05623033
- Testing
- The study is an observational study without intervention
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Tuberculosis
A Leukapheresis Study for Immune Responses in Healthy US Adults Who Receive BCG Vaccination Followed by Boosting With AERAS-402
Healthy adults received BCG on Study Day -84, followed by randomization on Study Day 0 to receive 2 booster doses in a blinded fashion of either AERAS-402 (N=9) or placebo (N=2) on Study Days 0 and 28.
- Trial name
- C-021-402 (NCT02375256)
- Testing
- AERAS-402, BCG (1-8 x105 cfu ID)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Aeras
Hemodialysis Complication
Impact of Neutrophil Lymphocyte and Monocyte Lymphocyte Ratio on Chronic Kidney Disease Patients Outcome
The aim of this study is to establish NLR, MLR as a good predictors for outcome of CKD including hemodialysis and CKD stage (4-5) patients as regard inflammation, malnutrition and anemia on cardiovascular complication.
- Trial name
- NCT05887960
- Testing
- CBC and flow cytometry test for monocyte
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
NK Cell Mediated Immunity, NK Cell Cytokine Production
Cellular Immunity and Renal Cell Cancer
Renal cell cancer (RCC) is one of the most important urogenital tumors because of it's high mortality and increasing incidence. RCC, which accounts about 3% of all malignant tumors in the adults, is the most lethal urogenital…
- Conditions
- NK Cell Mediated Immunity, NK Cell Cytokine Production, Kidney Cancer
- Trial name
- NCT04377113
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka