Clinical trials: Lymphoedema
Cancer, Oedema
Measuring Fluid Buildup in Cancer Patients
The goal of this study is to improve the monitoring of fluid retention in cancer patients. The main question it aims to answer is: Can segmental bioelectrical impedance analysis be used to monitor local fluid retention (edema) in…
- Conditions
- Cancer, Oedema, Bioelectrical Impedance, Lymphoedema
- Trial name
- NCT07443618
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Jens Rikardt Andersen
Limb Lymphoedema
Clinical Study to Assess the Efficacy and Pressure Maintenance of MOBIDERM Autofit Versus Bandages in the Management of Breast Cancer Related Lymphedema (BCRL) in Night-time Maintenance Phase.
The aim of this cross-over, randomized study is to assess the efficacy and pressure maintenance of MOBIDERM Autofit versus bandages in the management of Breast Cancer Related Lymphedema (BCRL) in night-time maintenance phase.
- Trial name
- MOBISCAN (NCT07355959)
- Testing
- MOBIDERM Autofit Armsleeve, Self-bandages
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Thuasne
Breast Edema, Breast Cancer Related Lymphoedema
Effectiveness of Kinesio Taping in Patients With Chronic Breast and/or Truncal Oedema After Treatment for Breast Cancer.
The goal of the KiTaLymph trial is to investigate whether the application of kinesio tape is effective in women with persistent (>6 months) breast and/or truncal oedema after treatment for breast cancer.
- Conditions
- Breast Edema, Breast Cancer Related Lymphoedema, Breast Cancer Related Lymphedema, Truncal Lymphedema
- Trial name
- KiTaLymph (NCT07080476)
- Testing
- Decongestive lymphatic therapy, Kinesio tape, Compression bra (sub-study)
- Where
- 4 sites in Belgium
- Volunteers
- 128 people
- Sponsor
- Universiteit Antwerpen
Lymphedema, Lymphoedema
Effect of Lymphovenous Anastomosis on Lower Limb Lymphedema: Pragmatic Randomized Controlled Trial
This multicentre pragmatic randomised controlled trial evaluates lymphovenous anastomosis (LVA) for lower-limb lymphedema (LLL) in Denmark.
- Conditions
- Lymphedema, Lymphoedema, Lymphoedema of Leg, Lymphedema of Leg
- Trial name
- NCT07073586
- Testing
- Lymphovenous Anastomosis, Complete Decongestive Therapy
- Where
- 2 sites in Denmark
- Volunteers
- 66 people
- Sponsor
- Herlev and Gentofte Hospital
Lymphoedema
Subclinical Monitoring of Lymphatic Function in Oncology Patients for Lymphoedema Prevention (ONCOLYMPH)
Lymphoedema, a chronic condition caused by the accumulation of protein-rich fluid in the intercellular spaces due to impaired lymphatic function, is a common complication in cancer patients.
- Trial name
- ONCOLYMPH (NCT07011316)
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- The Greater Poland Cancer Centre
Lymphoedema of Leg, Lymphedema Arm
Added Value of Reconstructive Lymphatic Surgery to Usual Care in Lymphoedema
The primary objective of this research proposal is to investigate in patients with lymphoedema of the upper limb or lower limb (P) the added value of reconstructive lymphatic surgery (I) to the decongestive lymphatic therapy…
- Conditions
- Lymphoedema of Leg, Lymphedema Arm, Lymphedema
- Trial name
- SurLym (NCT05064176)
- Testing
- Usual care, Reconstructive lymphatic surgery
- Where
- 3 sites in Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer Related Lymphoedema, Lymphoedema
LYT-100 in Patients With BCRL
This is a trial of up to 6-months duration for safety, tolerability, clinical efficacy assessments, PK and biomarkers analysis in breast carcinoma patients with secondary lymphoedema
- Trial name
- NCT04243837
- Testing
- LYT-100 BCRL
- Where
- 8 sites in United States, Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PureTech
Lymphoedema, Breast Cancer
Spa Therapy for Upper or Lower Limb Lymphoedema
THERMOEDEME is a comparative, controlled, randomized, multicenter and simple blinded (investigator) trial. The aim of this study is to evaluate effects of spa therapy in phlebology with a therapeutic education program in daily…
- Conditions
- Lymphoedema, Breast Cancer, Malignant Disease, Gynaecological Cancer
- Trial name
- THERMOEDEME (NCT03580109)
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 160 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Breast Cancer Related Lymphoedema
Manual Lymphatic Drainage Versus Standard Treatment for the Prevention of Breast Cancer-related Lymphoedema in Patients Who Undergo Axillary Node Clearance
Axillary lymph nodes are the main site of metastasis in breast cancer. If positive axillary lymph nodes are present, an axillary lymph node dissection (ALND) is usually performed.
- Trial name
- BCRL (NCT04582565)
- Testing
- Decongestive lymphatic therapy (DLT), Standard Care
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Lymphoedema
Prospective Observational Lymphoedema Intensive Treatment
The aim of this observational study was to describe usual practices in lymphedema management in France. It was the opportunity to assess the effects of these practices on lymphedema volume in a large number of patients, to…
- Trial name
- POLIT (NCT01864044)
- Volunteers
- 306 people
- Sponsor
- Thuasne
Lymphoedema, Breast Cancer
Effect of Physical Therapy on Breast Cancer Related Lymphedema
The objective of this study is to investigate if Complete Decongestive Therapy is equally effective whether it includes manual lymphatic drainage or not in the treatment of lymphoedema among patients with breast cancer.
- Trial name
- NCT02015897
- Testing
- Physical TherapyA, Physical TherapyB
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Lymphoedema
Comparison of Two Types of Bandages in the Treatment of Lymphoedema
The study is a cohort study of patients at the University Hospital during the first two days of intensive treatment. The patients are randomly divided into two groups (N=10).
- Trial name
- NCT05169086
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Lower Extremity Lymphoedema, Leg Lymphoedema
Treatment Response to Different Lymphoedema Compression Programs Using a Pneumatic Compression Device
Proof of principle study in order to determine if there is a difference in treatment effect across the 3 study groups when treating lower extremity lymphoedema using a pneumatic compression device.
- Trial name
- NCT02031627
- Testing
- pneumatic compression - 1 hour per day, pneumatic compression - 2 hours per day, pneumatic compression - 4 hours per day
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Tactile Medical
Lymph Node Dissection, Lymphoedema
A Study for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection
Patients undergoing groin or axillary Radical lymph node dissection (RLND) or completion lymph node dissection (CLND, after positive sentinel lymph node biopsy (SLNB) for melanoma or breast cancer were randomized in a controlled…
- Conditions
- Lymph Node Dissection, Lymphoedema, Lymphocoele
- Trial name
- NCT02476357
- Testing
- Harmonic scalpel
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Lausanne Hospitals
Lymphoedema of Leg
Intermittent Pneumatic Compression for Treating Lower Limb Lymphoedema
The treatment of lymphoedema and its associated complications represent a considerable drain on increasingly limited NHS resources.
- Trial name
- IMPRESS II (NCT03856281)
- Testing
- Intermittent Pneumatic Compression
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cwm Taf University Health Board (NHS)
Lymphoedema
Intermittent Pneumatic Compression for Treating Lower Limb Lymphoedema
The treatment of lymphoedema and its associated complications represent a considerable drain on increasingly limited NHS resources.
- Trial name
- IMPRESS (NCT03825263)
- Testing
- Intermittent Pressure Compression
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of South Wales
Lymphoedema
A Clinical Trial About the Contribution of Manual Lymph Drainage in Complex Physical Therapy for Patients With Lymphoedema Secondary to Mastectomy
Hypothesis: To know the utility of manual lymph drainage (MLD) as part of the Physical Complex Therapy has turn out relevant because of the exclusive dedication that it supposes to the therapist.
- Trial name
- NCT01152099
- Testing
- Compression Bandaging, Manual Lymph Drainage (MLD) and Compression Bandaging
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Mansonelliasis, Pruritus
Epidemiology and Control of Mansonella Perstans Infection in Uganda
Mansonella perstans (M. perstans) infection is widespread in Uganda. Knowledge about the epidemiology of this infection, and of the morbidity it induces is poor, and no effective treatment is available.
- Conditions
- Mansonelliasis, Pruritus, Lymphoedema, Abdominal Pains
- Trial name
- NCT00215280
- Testing
- ivermectin and albendazole
- Where
- Uganda
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- DBL -Institute for Health Research and Development