Clinical trials: MGD
Breast Neoplasms, Ovarian Neoplasms
Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer
The primary purpose of this study is to evaluate the safety, side effects, and dosage for Motexafin Gadolinium given with the chemotherapy drug docetaxel to patients with advanced cancers.
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Lung Neoplasms
- Trial name
- NCT00120939
- Testing
- Motexafin Gadolinium
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Pharmacyclics LLC.
Dry Eye, Ocular Graft vs Host Disease
Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD)
The objective of this study is to establish whether patients with dry eye disease (DED) are able to tolerate receiving Brimonidine: 0.15% eye drops two times a day for twelve weeks (primary tolerability objective) and to…
- Conditions
- Dry Eye, Ocular Graft vs Host Disease, Meibomian Gland Dysfunction
- Trial name
- NCT02975557
- Testing
- Brimonidine 0.15%, Brimonidine 0.075%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Sandeep Jain, MD
MGD-Meibomian Gland Dysfunction
Efficacy of Adjunctive Low-Level Light Therapy to Intense Pulsed Light for Meibomian Gland Dysfunction
The goal of this clinical trial is to compare the effectiveness of adjunctive low-level light therapy (LLLT) to intense pulsed light (IPL) versus intense pulsed light (IPL) alone for the treatment of meibomian gland dysfunction…
- Trial name
- NCT06468930
- Testing
- Low-level light therapy (LLLT), Intense pulsed light (IPL)
- Where
- Thailand
- Volunteers
- 58 people
- Sponsor
- Chulalongkorn University
Dry Eye, Meibomian Gland Dysfunction
IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD
The aim of the current study is to examine the contribution of intense pulsed light (IPL) for relieving signs and symptoms of dry eye due to meibomian gland dysfunction.
- Trial name
- NCT03265652
- Testing
- Intense Pulsed Light (IPL) therapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Lumenis Be Ltd.
Evaporative Dry Eye
Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs
Dry eye disease (DED) is a widely spread disorder of tears and ocular surface affecting hundreds of millions around the world. Manifestations resulting from moderate to severe DED have significant effects on the patient's quality…
- Trial name
- NCT05331924
- Testing
- IPL therapy, Punctal plugs
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dry Eye, MGD-Meibomian Gland Dysfunction
Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops
A multicenter randomized controlled trial on prevention and treatment of ocular surface injury and meibomian gland dysfunction in patients using anti-glaucoma eye drops.
- Trial name
- NCT03515187
- Testing
- 0.3% sodium hyaluronate ophthalmic solution, 0.1% sodium bromide solution, Meibomian gland massage
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hospital of Southern Medical University
Breast Neoplasms, Ovarian Neoplasms
Study of Motexafin Gadolinium and Docetaxel for Advanced Solid Tumors
The primary purpose of this study is to evaluate the safety, toxicities, and dosage for investigational drug Motexafin Gadolinium administered with docetaxel to patients with advanced solid tumors.
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Lung Neoplasms
- Trial name
- NCT00080041
- Testing
- Motexafin Gadolinium Injection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pharmacyclics LLC.
Ss-octa, Lid Margin Blood Flow Density
Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA
To explore an optimized scan technique for the detection of lid margin vasculature
- Conditions
- Ss-octa, Lid Margin Blood Flow Density, MGD
- Trial name
- NCT06091722
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Meibomian Gland Dysfunction, Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion…
- Trial name
- NCT05306561
- Testing
- Systane iLux thermal pulsation treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Periman Eye Institute
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Study of Weekly Motexafin Gadolinium (MGd) for Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
The primary purpose of this study is to evaluate the safety, toxicities, dosage and response rate for an investigational drug, motexafin gadolinium, administered to patients with chronic lymphocytic leukemia or small lymphocytic…
- Conditions
- Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Leukemia, Lymphoma
- Trial name
- NCT00290004
- Testing
- motexafin gadolinium
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Pharmacyclics LLC.
Dry Eye Syndromes, Meibomian Gland Dysfunction
Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD
The goal of this prospective, 24-week, double-masked, randomized, sham-controlled clinical trials to compare clinical efficacy and safety of RF and MGX with MGX alone in patients with meibomian gland dysfunction-related dry eye…
- Trial name
- NCT06220474
- Testing
- The Thermage FLX System
- Where
- 2 sites in Hong Kong
- Volunteers
- 112 people
- Sponsor
- The University of Hong Kong