Clinical trials: MPM
Bronchial Neoplasm Benign
Survivin and Fibulin-3 in Benign and Malignant Respiratory Diseases
Purpose: Survivin is a common member of the inhibitors of the apoptosis protein (IAP) family with a dual role in promoting cell proliferation and preventing apoptosis.
- Trial name
- NCT04413292
- Testing
- ELISA assays and Westren blot analysis of survivin and fibulin-3 expression
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- South Valley University
Bladder Cancer, Prostate Cancer
Use of Multiphoton Microscopy in the Diagnosis of Cancer
Multiphoton microscopy (MPM) has been shown to be able to image tissue at a cellular level. Our project will initially evaluated the ability of MPM imaging to distinguish normal bladder urothelium from atypical and malignant…
- Trial name
- MPM (NCT00652210)
- Testing
- Multiphoton microscopy
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Collagen Fibril Alteration
Assessing the Effects of Tretinoin Cream on Human Skin With Optical Imaging Technologies
The researchers will assess the effects of treatment with tretinoin cream on human skin by using non-invasive optical imaging technologies.
- Trial name
- NCT02410980
- Testing
- Tretinoin cream 0.1%
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Abnormal Vascular Flow
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin.
- Trial name
- NCT01484730
- Testing
- Multi-Spectral and Laser Speckle Imaging
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Bone Graft; Complications
Socket Preservation Using Autogenous Bone Graft Versus MPM
Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.
- Trial name
- NCT03008538
- Testing
- MPM(Mineralized plasmatic matrix)., Autogenous Bone Graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgical Wound, Healed
MPM Medical CoMatryx Surgical Bovine Collagen Study
The objective of this prospective enrollment study is to collect data confirming safety, performance and clinical benefits of the CoMatryx Surgical Collagen powder at a minimum 1-year follow-up and compare it to a historical…
- Trial name
- NCT04407364
- Testing
- CoMatryx Surgical Bovine Collagen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MPM Medical
Cleft; Alveolar Process
Evaluation of MPM Prepared From Allogenic Bone Graft in Alveolar Cleft Closure: A Prospective Randomized Clinical Trial
The aim of this trial is to figure out the efficiency of Mineralized Plasmatic Matrix prepared from allogenic bone graft on cleft alveolus and oro-nasal fistula closure, adequate bone volume and acceptable density at the site of…
- Trial name
- NCT03420287
- Testing
- MPM Prepared From Allogenic Bone Graft, Autogenous bone
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mesothelioma, Malignant Pleural
Genetic Susceptibility in MAlignant Pleural Mesothelioma: Clinical Implication of GermliNE variaTionS
Malignant pleural mesothelioma (MPM) is a rare and aggressive neoplasm of the pleural mesothelium, mainly associated to asbestos exposure, still lacking effective therapies.
- Trial name
- MAGNETS (NCT06886672)
- Where
- 2 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Bone Resorption
Preimplant Site Augmentation Using MPM Versus Autogenous Bone Graft
Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards.
- Trial name
- NCT03007069
- Testing
- Mineralized plasmatic matrix (MPM)., Autogenous bone graft (gold standard).
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Lesion
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.
- Trial name
- NCT01771718
- Testing
- Multiphoton microscopy-based tomograph.
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Healthy
Evaluating Light-tissue Reaction and Transdermal Drug Delivery by Multiphoton Microscopy
In this study, the investigators will evaluate the potential of multiphoton microscopy as a non-invasive imaging modality for monitoring of the radiofrequency-tissue and light-tissue reaction.
- Trial name
- NCT01355328
- Testing
- laser and radiofrequency
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Mesothelioma
Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM
Primary Objective To determine the maximum tolerated dose (MTD) of intrathoracic administration of pemetrexed when given in conjunction with cisplatin in patients with resectable malignant pleural mesothelioma MPM.
- Trial name
- NCT02838745
- Testing
- Pemetrexed, Cisplatin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine