Clinical trials: MRI
Healthy
Mapping of the Human Brainstem During Continence and Micturition: Noninvasive 7-T fMRI Study
The lower urinary tract (bladder, bladder neck, urethra and urethral sphincter) has two functions: Storage (Continence) and voiding (micturition).
- Trial name
- NCT04846387
- Testing
- Magnetic Resonance Imaging (MRI), Post-Void Residual, Uroflowmetry
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Labor Pain, Pain Relief
fMRI Measurements on Pain Relief Methods in First Stage Labor Pain
The purposes of this study is to integrate the objective tests into the subjective test, visual analog score (VAS), for evaluation and further understanding of relieving labor pain by TENS application on acupuncture points in the…
- Conditions
- Labor Pain, Pain Relief, Magnetic Resonance Imaging
- Trial name
- TENS (NCT00768014)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dysmenorrhea
Brain Structural and Functional Connectivity Changes in the Period of Dysmenorrhea: a Prospective fMRI Study
Observational prospective study with an analysis of the changes in brain structure and related functional connectivity in women with dysmenorrhea.
- Trial name
- NCT06178406
- Testing
- dysmenorrhea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiac Resynchronization Therapy, Magnetic Resonance Imaging (MRI)
MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)
The goals of this project are to: 1) explore the potential use of magnetic resonance imaging (MRI) data for improved prediction of response to cardiac resynchronization (CRT), and 2) use the MRI-derived data together with a…
- Trial name
- NCT02728336
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Regional Anesthesia Morbidity, Postoperative Pain
Local Anesthesia Spread After an Erector Spinae Plane Block.
This a single-center prospective spread-evaluation study where the primary objective is to assess the spread of local anesthesia in an ESPB using magnetic resonance imaging (MRI).
- Trial name
- NCT05012332
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Portal Hypertension, Liver Diseases
Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment
Liver cirrhosis is a chronic disease characterized by a progressive accumulation of fibrosis, loss of liver function and portal hypertension leading to several hemodynamic changes.The exact pathophysiological mechanisms causing…
- Conditions
- Portal Hypertension, Liver Diseases, Liver Cirrhoses, Cirrhosis
- Trial name
- NCT03443934
- Where
- Denmark
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Type 2 Diabetes, Insulin Resistance
Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus）
This is a cross-sectional and longitudinal study to investigate the characteristic changes in Papez's circuit neural network activity and connectivity based on multimodal MRI, and through follow-up study of the interaction…
- Conditions
- Type 2 Diabetes, Insulin Resistance, Cognitive Impairment
- Trial name
- T2DM (NCT06912321)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Breast Cancer
Sodium (23Na) MRI for Tumour Characterisation and Assessment of Therapy Response in Breast Cancer
The scope of this study is the methodological development and optimisation of sodium MRI (23Na-MRI) protocols for breast cancer imaging.
- Trial name
- NaRNIA (NCT03940092)
- Testing
- MRI, PET/MRI
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Asthma, COPD
MagniXene MRI Use in Patients With Asthma and COPD to Assess Regional Lung Function by Delineating Ventilation Defects
The purpose of this clinical trial is to demonstrate hyperpolarized xenon (HXe) as a medical imaging drug (agent) for Magnetic Resonance Imaging (MRI) of the human lung ventilation.
- Conditions
- Asthma, COPD, Healthy
- Trial name
- HXe-VENT (NCT01833390)
- Testing
- HXe MRI lung ventilation
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Xemed LLC
Bereavement, Healthy
The Impact of Familiarity and Emotional Attachment on the Visual Processing of Faces
This study uses functional magnetic resonance imaging (fMRI) to look at brain activity while patients view pictures of people's faces that they are familiar with or have emotional attachment to.
- Trial name
- NCT00001913
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Vascular Diseases, Myocardial Ischemia
Assessment of Oxygen Changes in the Heart With Cardio-vascular Magnetic Resonance Imaging
The ability of a new SSFP-based BOLD MRI sequence to assess myocardial oxygenation changes in response to coronary flow changes induced by adenosine and increased CO2-partial pressure will be examined in healthy volunteers and…
- Trial name
- NCT00693758
- Testing
- adenosine, modified end-tidal forcing system, arm cuff occlusion
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Back Pain, X-rays
Natural Experiment: "Gentle Nudge" Intervention, Eliminating Phone Call Requirement
Back pain costs the U.S. over $100 billion annually, and much of this spending is wasteful due to the overuse of advanced diagnostic imaging.
- Conditions
- Back Pain, X-rays, MRI, CT Scan
- Trial name
- LBP-ED (NCT03381885)
- Testing
- Gentle Nudge, Usual Standard Procedure
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Late Life Depression
TBS,TMS, Suicidal Ideation, Magnetic Resonance Imaging, Dorsolateral Prefrontal Cortex, Ventrolateral Prefrontal Cortex
Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique, its approved therapeutic indication is high-frequency stimulation to the left dorsolateral prefrontal cortex (DLPFC) for treatment resistant.
- Trial name
- NCT05010915
- Testing
- Transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mindfulness, Stress
Scrutinizing and Promoting Mindfulness Via New Technologies
The overall goal of the outlined study is to scrutinize and to promote mindfulness via new technologies using a combination of smartphone-based assessment and micro-interventions, fMRI and real-time fMRI-neurofeedback.
- Conditions
- Mindfulness, Stress, Mood, Working Memory
- Trial name
- NCT03148678
- Testing
- Mindfulness, Contingent RT-fMRI-NF, Mind Wandering
- Where
- 2 sites in South Korea, Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
MRI, PTX
MR7T-Healthy-PTX : Brain Exploration in Magnetic Resonance Imaging in Parallel Transmission Mode (pTX) at 7 Tesla
Magnetic resonance imaging (MRI) is a non-invasive imaging modality used in routine clinical practice for clinical diagnosis by visualizing the anatomical structure and in vivo function of certain organs.
- Conditions
- MRI, PTX, BRAIN, 7 TESLA
- Trial name
- NCT04369755
- Testing
- MRI
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Radiation Therapy
Imaging Acquisition and Analysis Methods for Optimization of MRI Radiation Oncology Simulation and Response Assessment
Magnetic resonance imaging (MRI) is currently one of the standard diagnostic imaging methods used to diagnose tumor stage before treatment in the Radiation Oncology Department.
- Trial name
- NCT02422550
- Testing
- MRI or CT
- Where
- 7 sites in United States
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy
Use of Transcranial Magnetic Stimulation (TMS) and Magnetic Resonance Imaging (MRI) to Study Visual Attention
The purpose of this study is to learn more about how the brain allows people to focus on important objects and filter out unimportant ones when looking at visual images.
- Trial name
- NCT00006285
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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