Clinical trials: MRI Imaging
Traumatic Brain Injury, Aging Disorder
Carbon Dioxide Administration and Brain Waste Clearance
The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood.
- Conditions
- Traumatic Brain Injury, Aging Disorder, Magnetic Resonance Imaging (MRI)
- Trial name
- COPETBI (NCT07357090)
- Testing
- Hypercapnia task performed during fMRI
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrew Mayer
Cardiac Resynchronization Therapy, Magnetic Resonance Imaging (MRI)
MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)
The goals of this project are to: 1) explore the potential use of magnetic resonance imaging (MRI) data for improved prediction of response to cardiac resynchronization (CRT), and 2) use the MRI-derived data together with a…
- Trial name
- NCT02728336
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Whole Body Imaging, Prostate
AI Technologies for Enhanced and Celerated High-Field WB-MRI
Single-center, cross-sectional observational study assessing the feasibility of advanced accelerated MRI sequences versus standard ones in terms of image quality, diagnostic reliability, and acquisition time.
- Conditions
- Whole Body Imaging, Prostate, MRI, Lung
- Trial name
- AITECH-MRI (NCT07678320)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Breathing, Lung Function Decreased
Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function
This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.
- Conditions
- Breathing, Lung Function Decreased, MRI Imaging, Healthy
- Trial name
- PROOF (NCT07614685)
- Testing
- Airway Oscillometer, Phase Resolved Functional Lung MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Neoplasms, Artificial Intelligence (AI)
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement
This study is conducted under the ethics-approved project titled "Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI''.The goal of this observational study is to develop an integrated breast…
- Conditions
- Breast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance Imaging
- Trial name
- NCT07598084
- Testing
- Non-contrast breast MRI diagnostic model
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Contrast Agent, Medical Imaging Data
ELUDYN: Assessment of Intra-individual Variability of Vascular Dynamics of Gadopiclenol Injection Parameters in Contrast-enhanced MRI
This study aims to understand how the volumes and speeds of intravenous injection of a recent type of contrast agent can be optimized in order to improve the information provided by medical images.
- Conditions
- Contrast Agent, Medical Imaging Data, MRI Image Enhancement
- Trial name
- ELUDYN (NCT07346131)
- Testing
- contrast agent, Gadolinium
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Respiratory Amplitude, Portal Blood Flow
Variations of Portal Flow During the Respiratory Cycle in Healthy Volunteers
The analysis of portal vein blood flow is important when assessing the severity and progression of liver disease. It is important to understand normal liver regulation in order to appreciate the evaluation of the effect of…
- Conditions
- Respiratory Amplitude, Portal Blood Flow, MRI, Echo Planar Imaging
- Trial name
- RESPIFLUX (NCT04782531)
- Testing
- peripheral ECG, Standard MRI
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
IVF, Frozen Embryo Transfer (FET)
Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)
Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).
- Conditions
- IVF, Frozen Embryo Transfer (FET), Cardiovascular Adaption, Magnetic Resonance Imaging (MRI)
- Trial name
- NCT06471140
- Testing
- magnetic resonance imaging (MRI)
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Hypothyroidism, Anesthesia, General
Effect of Brain GABA Metabolite Amount to Propofol Utilisation Under TIVA in Hypothyroid Patient
Introduction: GABAergic synaptic transmigration in the anterior cingulate (ACC) cortex of hypothyroid rats has been demonstrated by electrophysiologic recordings.
- Conditions
- Hypothyroidism, Anesthesia, General, Propofol Dosage, Magnetic Resonance Imaging (MRI)
- Trial name
- BrainGABA (NCT06649318)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duzce University
Parkinson Disease, Movement Disorders
Multimodal Image Technologies Investigate the Role and Mechanism of Probiotics in Improving RBD with Parkinson's Disease
Rapid eye movement sleep behavior disorder (RBD) is important non-movement feature, and also the important risk factor of Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Movement Disorders, Rapid Eye Movement Sleep Behavior Disorder, Gut Microbiomes
- Trial name
- NCT06710574
- Testing
- PD-RBD, iRBD
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
MRI Imaging
Assessment of Investigational Magnetic Resonance Imaging and Post-Processing Procedures
The goals of this study are to (1) develop and optimize MRI acquisition and post-processing techniques and (2) to generate preliminary and comparative data on sequences for potential clinical trials.
- Trial name
- NCT03490656
- Testing
- MRI Scan - in addition to standard of care, MRI Scan - not in addition to standard of care
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Imaging Data Collection From Dynamic Swallowing MRI in Healthy Volunteers, Create Operating Algorithms
Transposition of Dynamic MRI Data From Healthy Subjects to an in Vitro Swallowing Simulator
Swallowing is a complex process, involving a very fine synchronization of the pharyngo-larynx, with respiration, under the control of the central nervous system and numerous peripheral effectors.
- Conditions
- Imaging Data Collection From Dynamic Swallowing MRI in Healthy Volunteers, Create Operating Algorithms, Apply the Imaging Data of MRI to a Swallowing Simulator
- Trial name
- SWALL-E (NCT05178108)
- Testing
- Real-time MRI of swallowing
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Radiculopathy Lumbar, MRI
Diffusion Tensor Sequences (DTI) for Study of Lumbar Roots by Magnetic Resonance Imaging (MRI)
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Radiculopathy Lumbar, MRI, Diffusion Tensor Imaging
- Trial name
- OPTI-DTI (NCT04224077)
- Testing
- Optimisation of DTI sequences
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Cerebral Perfusion Pressure, Vasopressor Agents
Physiologic Study of Cerebral Perfusion
The aim of the study is to measure cerebral perfusion using MRI in healthy subjects (with and without sedation) and in vasopressor-dependent patients
- Conditions
- Cerebral Perfusion Pressure, Vasopressor Agents, Shock, Magnetic Resonance Imaging (MRI), Functional
- Trial name
- NCT02744625
- Testing
- Higher doses of vasopressor therapy for a MAP of 75 mmHg, Lower doses of vasopressor therapy for a MAP of 65 mmHg, Propofol for light sedation
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
F-MRI Brain Imaging Data
Exploring Medical Decisions Using Functional MRI
Hospital physicians are increasingly facing budgetary constraints that might have an impact on individual medical decisions (i.e. diagnostic or therapeutic decisions). This might translate into role conflict and ambiguity.
- Trial name
- NCT02994004
- Testing
- no intervention
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier