Clinical trials: MYOPATHY
Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease
Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan
Inborn errors of metabolism (IEM) are not have specific clinical signs, they masquerade as other diseases, and are difficult to diagnose using only clinical manifestations or routine laboratory tests.
- Conditions
- Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease, Citrullinemia, Argininosuccinic Aciduria
- Trial name
- NCT05910151
- Testing
- Obtaining Dry Blood Spots From Healthy Newborns (Aged 1-7 Days), Obtaining Dry Blood Spots From Healthy Children Aged 8 Days - 7 Years, Obtaining Dry Blood Spots From Healthy Children Aged 8-18 Years
- Where
- Kazakhstan
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- West Kazakhstan Medical University
Pre - Delivery Pregnant Women, Chronic Pain
Assessment of Central Pain in the Peripartum Period
Chronic pain is common. Up to 10% of the Population has been estimated to suffer from chronic pain and up to 5% of the female population has been estimated to suffer from widespread, chronic pain and tenderness, thus fulfilling…
- Conditions
- Pre - Delivery Pregnant Women, Chronic Pain, Pain During Delivery
- Trial name
- NCT01291680
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cerebral Palsy, Spasticity
Power Wheelchair Joystick Use in Spastic Cerebral Palsy
There are over 750,000 individuals in the U.S. with Cerebral Palsy (CP). Up to 46% of adults with CP report limited mobility in their communities.
- Trial name
- NCT00337688
- Testing
- isometric joystick
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Deep Breathing Maneuver, PROGRESSIVE MUSCLE RELAXATION EXERCISES
SHORT-TERM EFFECTS OF DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES ON MUSCULOSKELETAL PAIN AND WELL-BEING IN HIGH SCHOOL STUDENTS
Exam stress in high school students, long hours of studying in the static posture, and lack of physical activity habits can cause physical and psychological discomfort in them.
- Trial name
- Deep breathing (NCT06972173)
- Testing
- DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Rheumatoid Arthritis, Spondylitis, Ankylosing
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Introduction: Patients with autoimmune rheumatic diseases (ARDs), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PAs), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), primary…
- Conditions
- Rheumatoid Arthritis, Spondylitis, Ankylosing, Spondyloarthritis, Systemic Lupus Erythematosus
- Trial name
- RZVRheum (NCT05879419)
- Testing
- Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation
- Where
- Brazil
- Volunteers
- 2,005 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Neck Pain
Sensory Characteristics and Psychosocial Factors Related With Non-specific Neck Musculoskeletal Pain Chronification
Chronic pain is commonly defined as any pain which lasts more than 12 weeks. Chronic non-specific neck pain (CNSNP) has no specific underlying disease causing the pain.
- Trial name
- CNSNP (NCT04330573)
- Testing
- No intervention. Observational study
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Fibromyalgia Syndrome
Sleep Disturbance and Sleep Quality in Women With Fibromyalgia Syndrome
The purpose of this week long study is to describe sleep and problems with sleep in women diagnosed with Fibromyalgia syndrome.
- Trial name
- NCT00482859
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Weakness, Muscle
Blood Flow Restriction Training for People With Disabilities
A large portion of the American population live with disabilities. People with disabilities can find it difficult to perform standard exercise routines. Regular exercise is necessary to be healthy, especially as people age.
- Trial name
- NCT06441422
- Testing
- Blood flow restriction training, No blood flow restriction training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Injuries, Spinal Cord, CVA (Cerebrovascular Accident)
Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)
Comparing the efficacy of Intracthecal Baclofen dose between the Prometra II and Medtronic SynchroMed II for patients with spasticity and with current a current SyncroMed II pump needing replacement.
- Conditions
- Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis)
- Trial name
- NCT04530955
- Testing
- Prometra II Programmable Pump - Flowonix Medical
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Culicchia Neurological Clinic
Fibromyalgia
Tension-Type Headache and Masseter Thickness in Fibromyalgia
This study aims to investigate the relationship between tension-type headaches and masseter muscle thickness in women with fibromyalgia syndrome (FMS) and to explore the potential for new therapeutic approaches in the treatment…
- Trial name
- NCT06713278
- Testing
- masseter muscle thickness measurement, scales
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME
Progressive Muscle Relaxation According to Jacobson in Treatment of the Patients With Temporomandibular Joint Disorders
Temporomandibular joint disorders are ranked third among the most common stomatological diseases after dental caries and periodontal problems.
- Trial name
- NCT03622684
- Testing
- Muscle relaxation according to Jacobson
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Weakness, Muscle, Muscle Weakness
Short Term Immobilization of the Lower Limb
The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function.
- Conditions
- Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy
- Trial name
- STILL (NCT05072652)
- Testing
- Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Spastic Cerebral Palsy (sCP)
Botulinum Neurotoxin for Children With CP: a Delicate Balance Between Clinical Benefits and Muscular Harm
A cross-sectional design study will be carried out to explore the morphological muscle properties and alterations in muscle composition on a macroscopic level in children with spastic cerebral palsy (CP).
- Trial name
- Bo-Balance (NCT06991725)
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Muscle Weakness
Ventilatory Muscle Training by Breath-Stacking in Healthy Youngsters
In several diseases in which muscle weakness is a determining factor for morbidity and mortality, inspiratory muscle training has been shown to be useful in improving the function of ventilatory muscles, delaying or minimizing…
- Trial name
- NCT03258944
- Testing
- Breath-Stacking
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Musculoskeletal Pain, Neck Pain
Musculoskeletal Pain of Neck and Shoulder Area in Female Office Workers: Relations Between Muscle Tone, Stiffness, Pain-pressure Threshold, Self-reported Pain Intensity and Physical Activity.
The objective of this study is to determine the differences between neck and shoulder region skeletal muscle tone, stifness, pain-pressure threshold, self-reported pain intensity and physical activity in female office workers.
- Conditions
- Musculoskeletal Pain, Neck Pain, Shoulder Pain
- Trial name
- NCT04254276
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Muscle Weakness
Effects of Simultaneous Balance and Resistance Training in Older Adults
Aging results in a gradual decline of physical abilities and consequently in functional impairments which increases the risk of falls in elderly people.
- Trial name
- NCT02555033
- Testing
- Resistance training, Instability resistance training
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Kassel
Breast Feeding
Scapular Stabilization Exercises Combined With Thoracic Mobilization in Breast Feeding Mothers With Upper Back Pain
Upper-back pain is common among breastfeeding mothers and may be associated with prolonged feeding positions, forward-bent posture, reduced thoracic mobility, and weakness of the muscles controlling the shoulder blades.
- Trial name
- NCT07766148
- Testing
- Scapular Stabilization Exercises, Thoracic Spine Mobilization
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Myotonic Dystrophy Type 1
Children's Health Research Institute(CHRI), Stanford Lucile Packard Children Hospital (LPCH) Protocol on Myotonic Dystrophy
Study to focus on the defining and managing the neuropsychological abnormalities of myotonic dystrophy and to find out if the neuropsychological abnormalities have any correlation with changes seen on Magnetic Resonance Imaging.
- Trial name
- CHRI (NCT02269865)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lateral Epicondylitis
Lateral Epicondylitis Treatment High Intensive Laser Therapy and Extracorporeal Shock Wave Therapy
Objectives: This study aims to evaluate and compare the short-term efficacy of high-intensity laser therapy (HILT) and extra corporeal shock wave therapy(ESWT) on pain, sensitivity, handgrip strength, and functions in the…
- Trial name
- NCT06301152
- Testing
- high intensive laser, extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
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