Clinical trials: MYOPATHY
Muscle Disorder
Measurement of the Distribution of Optical Properties in Adult Human Muscle
The researcher can use Diffuse Optical spectroscopy technique that uses harmless levels of near-infrared light to probe the concentrations and states of important physiological molecules such as hemoglobin water and lipids in…
- Trial name
- NCT00540683
- Testing
- Diffuse Optical Spectroscopy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Fibromyalgia, Ankylosing Spondylitis
Frequency of Axial Spondyloarthropathy Among Patients Suffering From Fibromyalgia
Fibromyalgia Syndrome (FMS) is a non - inflammatory condition characterized by the presence of chronic, widespread musculoskeletal pain and tenderness; FMS is considered to be the result of increased processing of pain by the…
- Trial name
- NCT01167413
- Testing
- Evaluation by manual Dolorimeter, SIJ imaging
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
End Stage Liver Disease
Evaluation of Frailty and Functional Capacity in End-Stage Liver Disease
Development of fibrosis plays a main role in the pathophysiology of liver diseases. The rate of progression in fibrogenesis varies according to the type of underlying liver disease and varies with the environment and host-related…
- Trial name
- NCT04220723
- Testing
- Frailty Assessment, Functional Capacity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dupuytren Contracture, Disease Progression
Natural Disease Progress of Dupuytren Disease
Dupuytren disease (DD) is a progressive fibromatosis of the palmar fascias of the hand and fingers, which may lead to extension deficits of the fingers.
- Trial name
- DD (NCT01923103)
- Where
- Netherlands
- Volunteers
- 261 people
- Sponsor
- University Medical Center Groningen
Fibromyalgia
CBD (Cannabidiol)/THC (Tetrahydrocannabinol) Solution as a Pharmacological Strategy for Patients With Fibromyalgia (FibroCann)
Fibromyalgia is considered a chronic pain syndrome, non-inflammatory, of unknown etiology, which manifests itself in the musculoskeletal system in up to 2.5% of the general population, predominantly in females, mainly between 35…
- Trial name
- NCT05283161
- Testing
- cannabidiol and tetrahydrocannabinol
- Volunteers
- 40 people
- Sponsor
- FG Brasil LTDA
Spasticity, Spasticity in Participants With Multiple Sclerosis
Nerve Root Block in Spasticity
In this work the investigators propose to briefly apply kilohertz frequency alternating current via PNS device placed next to the isolated nerve in 4 patients undergoing peripheral neurectomy, just before cutting the nerve.
- Conditions
- Spasticity, Spasticity in Participants With Multiple Sclerosis, Spasticity Post Stroke, Spasticity Related to Any Cause Except Cerebral Palsy
- Trial name
- NCT06868342
- Testing
- High-frequency nerve conduction block
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Walton Centre NHS Foundation Trust
Sleep Bruxism, Masseter Muscle Hypertrophy
Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism
The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.
- Conditions
- Sleep Bruxism, Masseter Muscle Hypertrophy, Grinding Teeth
- Trial name
- EMG_BRUX (NCT06343194)
- Testing
- Bruxoff ®
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Muscle Weakness
Electromyography in Patients on Chronic Pyridostigmine Therapy
We intend to measure evoked EMG at two sites in subjects who are chronically taking pyridostigmine.
- Trial name
- NCT02364180
- Testing
- Electromyography (EMG)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Toledo Health Science Campus
Cerebral Palsy
Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for the Treatment of Cerebral Palsy
This is an Individual Patient Expanded Access Protocol of Autologous HB-adMSCs for the Treatment of Cerebral Palsy (CP) with the primary goal of treating 1 individual with CP who has exhausted all treatment options, his condition…
- Trial name
- NCT04029896
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Tendonitis
Pecs II Block Versus Surgeon Infiltration for Open Subpectoral Biceps Tenodesis
A phase IV, randomized, single-blind, single-center study measuring the effects of Pecs II block with 0.25% bupivacaine versus surgeon infiltration with 0.25% bupivacaine on postoperative pain control and opioid utilization in…
- Trial name
- NCT04867369
- Testing
- Bupivacaine 20mL 0.5%, Bupivacaine 20mL 0.25%, Bupivacaine up to 15mL 0.25%
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- NYU Langone Health
Myofascial Pain Syndrome - Neck
Comparing Physical Therapy Interventions on Craniovertebral Angle (CVA) in Cervical Myofascial Pain Syndrome (MPS)
Myofascial pain syndrome (MPS) and radiculopathy are prevalent musculoskeletal conditions that afflict a substantial portion of the population, causing significant discomfort and impairments in daily functioning.
- Trial name
- NCT07098754
- Testing
- Dry Needling, Trigger point therapy, Maitlands' Mobilizations
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- National Orthopedic and General Hospital
Systemic Hypertension, Muscle Weakness
Investigation of Factors Affecting Cardiorespiratory Fitness in Individuals With Systemic Hypertension
The investigators aim to investigate the factors affecting cardiorespiratory fitness in individuals with systemic hypertension.
- Conditions
- Systemic Hypertension, Muscle Weakness, Vascular Stiffness
- Trial name
- NCT04396405
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Neck Pain
Risk Factors and Risk Profiles for Persistent Neck Pain in Young Adults: Results From the HUNT Study
Neck pain is one of the most prevalent musculoskeletal disorder in Norway among older adolescents and young adults. Despite this, little research exist on risk factors for neck pain in the transitional life phase from adolescence…
- Trial name
- NCT04201366
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 8,562 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Lateral Epicondylitis, Elastography
Correlation of Ultrasonographic Findings With Clinical Parameters in Patients With Lateral Epicondylitis
Evaluation and Clinical Correlation of Tendons Using Power Doppler, SWE, Microvascular Flow (MV-Flow) Imaging and B-Mode Ultrasonography in Patients with Lateral Epicondylitis.
- Conditions
- Lateral Epicondylitis, Elastography, Ultrasonographic Diagnosis, Tennis Elbow
- Trial name
- NCT07127302
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ahmet Yesildag
Fibromyalgia, Posttraumatic Stress Disorder
Fibromyalgia in Men Suffering From PTSD
Assessing FM and psychiatric state among PTSD, MDD and healthy participants
- Conditions
- Fibromyalgia, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT00229294
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fibromyalgia
Efficacy of Acceptance and Commitment Therapy (ACT) in Group in Fibromyalgia
The main objective is to assess the efficacy of Acceptance \& Commitment Therapy (ACT) in group for the treatment of fibromyalgia.
- Trial name
- ACTGROUP (NCT01611831)
- Testing
- ACT in group, Improved treatment as usual by General Practitioners
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Dr. Marta Alda
Myotonic Disorders
Open-label Extension Study in Paediatric Patients Who Have Completed the MEX-NM-301 Study.
Open-label Extension Study to Evaluate the Long-term Safety and Efficacy of Mexiletine in Paediatric Patients with Myotonic Disorders Who Have Completed the MEX-NM-301 study.
- Trial name
- NCT04622553
- Testing
- Mexiletine
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Lupin Ltd.
Respiratory Disease, Muscle Weakness
Respiratory Muscle Training in Acquired Brain Injury Patients.
Background: Respiratory health problems are one of the main causes of morbidity and mortality in adult people with acquired brain injury (ABI).
- Conditions
- Respiratory Disease, Muscle Weakness, Acquired Brain Injury, Older People--Abuse of
- Trial name
- NCT06070831
- Testing
- Inspiratory muscle training, Expiratory muscle training
- Volunteers
- 26 people
- Sponsor
- University of Salamanca
Duchenne Muscular Dystrophy
A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren
This study is designed to generate additional data on the effect of ataluren for producing dystrophin protein in nonsense mutation nmDMD participants.
- Trial name
- NCT03796637
- Testing
- Ataluren
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- PTC Therapeutics
Electromyography, EMG: Myopathy
Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain
Chronic pelvic pain (CPP) is a common presenting complaint affecting approximately 15-40 % of women aged 18-50 in western countries and 5-43% of women in most developing countries.
- Conditions
- Electromyography, EMG: Myopathy, EMG Syndrome, Pelvic Pain
- Trial name
- SEMG (NCT03715777)
- Testing
- Clostridium botulinum type A (BoNTA)
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Jose Alberola-Rubio
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