Clinical trials: MYOPATHY
Intra-Abdominal Hypertension
First-In-Human Study of PDT to Detect IAH
PDT is a continuous pressure monitoring for Intra-Abdominal hypertension (IAH) designed to be less invasive than pan-endoscopic evaluation, more tolerable than abdominal tapping, and more effective than intravesical pressure…
- Trial name
- NCT06333366
- Testing
- Intra-gastrointestinal monitoring device (PDT)
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome
Effects of Masseter Manual Therapy on Temporomandibular Dysfunction
Muscles and myofascial dysfunction are more often the mechanism and source of pain in oral fascial disorders (OFD) than the TMJ.
- Conditions
- Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome, Temporomandibular Joint Disorder
- Trial name
- NCT00870922
- Testing
- Active release techniques
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Logan College of Chiropractic
Duchenne Muscular Dystrophy
Investigation of the Effects of Functional Inspiratory Muscle Training Applied With Tele-Rehabilitation on Respiratory and Functional Parameters and Quality of Life in Children With Duchenne Muscular Dystrophy: Randomized Controlled Study
Dushenne muscular dystrophy (DMD), which is characterized by the deficiency of dystrophin protein, prevents the muscle from maintaining its normal activity, causing progressive damage to the heart, respiratory muscles and…
- Trial name
- NCT07172737
- Testing
- Respiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Katip Celebi University
Chronic Pain, Musculoskeletal Pain
Brief Cognitive Behavioral Therapy for Chronic Pain
Brief Cognitive Behavioral Therapy for Chronic Pain (Brief CBT-CP) is designed specifically for use in integrated care settings.
- Trial name
- NCT03490981
- Testing
- Treatment as usual (TAU), Brief Cognitive Behavioral Therapy for Chronic Pain (Brief CBT-CP)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Covid19, Sarcopenia
Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection
With the COVID-19 pandemic, the number of patients to be treated in rehabilitation increased . Hospitalization for severe infection can induce muscular atrophy and muscular dysfunction that persists for several months and…
- Conditions
- Covid19, Sarcopenia, Muscle Weakness
- Trial name
- CovExc (NCT04649086)
- Testing
- Rehabilitation by Eccentric exercises, Rehabilitation by Concentric exercises
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Breast Neoplasms
Effect of Kinesiotaping for the Treatment of Hormone-induced Myalgia in Women Given Breast Cancer Survivors
Background: It has been demonstrated that aromatase inhibitors (AIs) are more effective than tamoxifen in reducing breast cancer recurrence.
- Trial name
- KITMYCAN (NCT02406794)
- Testing
- Neuromuscular taping
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- University of Malaga
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Venlafaxine, Pain
- Trial name
- NCT07186751
- Testing
- Pregabalin, Pregabalin with venlafaxine
- Where
- 2 sites in China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Knee Pain, Fibromyalgia
Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive
Background: pain lasting for 12 weeks or beyond, which is often referred to as chronic pain, is common for people living with musculoskeletal conditions (e.g. arthritis, low back pain and fibromyalgia).
- Trial name
- Pain-Drive (NCT07281651)
- Testing
- Central Pain Hypersensitivity
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Spinal Cord Injury, Spasticity
Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
Approximately 305,000 people live with a spinal cord injury (SCI) in the United States. Sixty percent of these individuals have tetraplegia, which can cause significant dysfunction of the arms and hands.
- Conditions
- Spinal Cord Injury, Spasticity, Shockwave Therapy
- Trial name
- NCT07501429
- Testing
- Focused extracorporeal shockwave therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Fibromyalgia
Self-guided Acceptance and Commitment Therapy-based Digital Smartphone Application for Management of Fibromyalgia
Introduction: Fibromyalgia (FM) is a prevalent syndrome that lacks curative treatment, imposing high healthcare and societal costs.
- Trial name
- SMART-FM-SP (NCT05962437)
- Testing
- Self-guided digital Acceptance and Commitment Therapy, FM symptom tracking app (FM-ST), Treatment as Usual (TAU)
- Where
- 2 sites in Spain
- Volunteers
- 360 people
- Sponsor
- Fundació Sant Joan de Déu
Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA)
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
The goal of this clinical trial is to evaluate whether the live attenuated tetravalent Butantan-Dengue vaccine (Butantan-DV) is safe and capable of inducing an immune response in patients aged 12 to 59 years with autoimmune…
- Conditions
- Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA), Systemic Lupus Erythematosus (SLE), Juvenile Systemic Lupus Erythematosus
- Trial name
- BTNDV-ARD (NCT07087912)
- Testing
- Dengue 1,2,3,4 (attenuated) vaccine
- Where
- 2 sites in Brazil
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Critical Illness, Acute Kidney Injury
Collective Accuryn Physiologic Signals and Signatures
The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Septic Shock
- Trial name
- CAPSS (NCT03817281)
- Testing
- Accuryn Monitoring System
- Where
- United States
- Sponsor
- Potrero Medical
Cerebral Palsy, Spastic Diplegia
MEOPA to Improve Physical Therapy Results After Multilevel Surgery
Children with cerebral palsy commonly undergo "multilevel surgery", meaning several lower limb combined procedures performed during the same surgical intervention.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Quadriplegia, Hemiplegia
- Trial name
- KINOPA (NCT00632528)
- Testing
- MEOPA, Medicinal air
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cramps, Chronic Kidney Disease(CKD)
Prevalence and Severity of Cramps in Chronic Kidney Disease Patients
Cramps are a frequent and severe complication in CKD patients. Their characteristics : triggering factors, associated factors, are not well known. There is no recognized effective treatment.
- Trial name
- CRAMéREIN (NCT06737094)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy
Effects of Dynamic Flex Cast With Neurodevelopmental Treatment on Gross Motor Functions in Cerebral Palsy
The study aims to determine the effects of dynamic flex cast with neurodevelopmental treatment on gross motor functions and gait in children with cerebral palsy.
- Trial name
- NCT05751122
- Testing
- Dynamic flex cast with neurodevelopmental treatment, Rigid Ankle foot Orthosis with neurodevelopmental treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Frailty, Muscle Weakness
Prognostic Value of Exhaled Isoprene Levels for Morbidity and Functional Outcome in Cardiosurgical Patients
The perioperative preservation of functionality and quality of life plays an increasingly important role in older physically limited and frail patients undergoing cardiac surgery.
- Conditions
- Frailty, Muscle Weakness, Volatile Organic Compounds, Isoprene
- Trial name
- PREDICT (NCT06175429)
- Testing
- Physical performance testing, Breath sampling and VOC analysis, Muscle ultrasound
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- University of Rostock
Dupuytren Contracture
Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release
The goal of this study is to learn about preventing recurrence of Dupuytren's Contracture. The main question it aims to answer are: Does targeted radiation therapy decrease recurrence of Dupuytren's contracture after treatment…
- Trial name
- NCT06330545
- Testing
- Radiation therapy
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chronic Pain, Fibromyalgia
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
Chronic pain disproportionately affects women and may coexist with impaired bone health, particularly during midlife and after menopause.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoporosis, Orofacial Pain
- Trial name
- ORION (NCT07783295)
- Testing
- Full-Spectrum Cannabis Extract 5:1 (CBD:THC)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Pain, Chronic, Fibromyalgia
Pain Neuroscience Education in Patients with Fibromyalgia
Many patients with fibromyalgia have little understanding of their condition, leading to maladaptive pain cognitions and coping strategies.
- Trial name
- NCT04050839
- Testing
- Pain neuroscience education, Medical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Fibromyalgia (FM)
Chronic Fibromyalgia Pain, Lifestyle Factors, and Inflammation
The goal of this observational study is to understand how lifestyle factors (such as diet, physical activity, sleep, stress, smoking, and alcohol intake) predict changes in pain sensitivity and modulation in adults aged 18-65…
- Trial name
- BUFS (NCT07074275)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bournemouth University
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