Clinical trials: MYOPATHY
Sporadic Inclusion Body Myositis (sIBM), Idiopathic Inflammatory Myopathies
Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Sporadic Inclusion Body Myositis
To evaluate the efficacy of Pozelimab/Cemdisiran combination therapy in patients with sIBM
- Trial name
- NCT06479863
- Testing
- Pozelimab/Cemdisiran
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Austin Neuromuscular Center
Stroke, Spasticity
Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients
Spasticity, muscle weakness, abnormal gait pattern are co-morbidities commonly seen in stroke patients. They cause disabled condition of patients in activities of daily life and functional performance, and also accidental falls…
- Trial name
- NCT01817816
- Testing
- Botox_A, Botox_B
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
SCI - Spinal Cord Injury, Spastic
"Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language"
To better depict the full range of spasticity after Spinal Cord Injury (SCI) there is a need to take into account the patients perspective and their experiences during daily life.
- Trial name
- SCI-SETde (NCT05022095)
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 65 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Dermatomyositis
Subcutaneous Immunoglobulin (Hizentra) in Patients With Dermatomyositis: A Proof of Concept Study
The purpose of the study is to evaluate the effectiveness and safety of human immunoglobulin SCIg in the form of Hizentra (Immune globulin Subcutaneous) in patients with Dermatomyositis.
- Trial name
- NCT02271165
- Testing
- Immunoglobulin (Hizentra)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Thomas Jefferson University
Hemophilia A
Joint Health, Balance and Quality of Life in Adults With Hemophilia A
Hemophilia is a hereditary bleeding disorder characterized by recurrent bleeding episodes, particularly into joints and muscles, leading to chronic musculoskeletal complications.
- Trial name
- NCT07523399
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Yuzuncu Yil University
Rheumatic Diseases, Temporomandibular Joint Dysfunction
Treatment in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction
This study was conducted to investigate the effect of manual therapy applications on pain, range of motion and joint position sense in individuals with rheumatoid arthritis who have temporomandibular joint dysfunction.
- Conditions
- Rheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel Therapy
- Trial name
- NCT07171671
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sanko University
Cerebral Palsy, Spastic
Stretching in Children and Adolescents With Spastic Cerebral Palsy
The primary aim of this study is to gain knowledge about both the effects of a single bout of static and proprioceptive neuromuscular facilitation (PNF) stretching and the effects of 8-week static and PNF stretching training on…
- Trial name
- NCT04570358
- Testing
- Static stretching, Proprioceptive neuromuscular facilitation stretching
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- University of Graz
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
GNE Myopathy, Hereditary Inclusion Body Myopathy
International GNE Myopathy Patient Registry
GNE myopathy, an ultra-rare disease, is a severe progressive myopathy that typically presents in early adulthood as weakness in the distal muscles of the lower extremities and progresses proximally, leading to a loss of muscle…
- Trial name
- NCT04009226
- Testing
- Patient Registry
- Where
- United Kingdom
- Volunteers
- 430 people
- Sponsor
- Newcastle University
Duchenne Muscular Dystrophy (DMD)
Study of Eteplirsen in DMD Patients
The main objective of this study is to provide evidence of efficacy of eteplirsen (AVI-4658) in Duchenne muscular dystrophy (DMD) patients that are amenable to skipping exon 51.
- Trial name
- PROMOVI (NCT02255552)
- Testing
- eteplirsen
- Where
- 37 sites in United States
- Volunteers
- 109 people
- Sponsor
- Sarepta Therapeutics, Inc.
Fibromyalgia
The Effects of Training and Relaxation on Fibromyalgia.
Effects of physical training and relaxation exercise on pathophysiological mechanisms and symptoms in finbromyalgia patients.
- Trial name
- NCT01226784
- Testing
- Physcial activity
- Where
- 3 sites in Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Spasticity in People With Multiple Sclerosis
Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis
Phase II a Proof of concept study in Multiple Sclerosis (MS) patients with spasticity.
- Trial name
- NCT02542787
- Testing
- VSN16R
- Where
- 4 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- Canbex Therapeutics Ltd
Tennis Elbow, Lateral Epicondylitis
Comparison of Two Different Treatment Effects on Individuals With Chronic Lateral Epicondylitis
The aim of this study is to compare the effects of Radial Extracorporeal Shockwave Therapy (rESWT) treatment and Deep Friction Massage (DFM) treatment on pain, functionality, grip strength (GS), edema, range of motion (ROM) of…
- Conditions
- Tennis Elbow, Lateral Epicondylitis, Tendinopathy
- Trial name
- NCT04187287
- Testing
- Radial Extracorporeal Shock Wave Therapy, Deep Friction Massage
- Where
- Cyprus
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Headache, Pain, Head
Pain Perception of People Who Are Unable to Have Headache
Headaches are extremely common illnesses with a combined lifetime prevalence of 90-99% in Europe. Despite this high prevalence, there are persons who have never, in their whole life, encountered a headache.
- Conditions
- Headache, Pain, Head, Muscle Tenderness, Healthy
- Trial name
- NCT04217616
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Danish Headache Center
Lateral Epicondylitis, High Intensity Laser Therapy
High and Low Dose High-intensity Laser Therapy Lateral Epicondylitis
High-intensity laser therapy has gained increasing attention in recent years as a therapeutic modality. It is a non-invasive treatment that can reduce pain, increase local blood circulation, and promote tissue repair.
- Conditions
- Lateral Epicondylitis, High Intensity Laser Therapy, Tennis Elbow, High Intensity Laser
- Trial name
- NCT07342426
- Testing
- High intensity laser therapy, Infarred ray therapy system, Transcutaneous electrical nerve stimulator
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Temporomandibular Disorders (TMD), Sleep
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
- Trial name
- Gnathology TMD (NCT06975709)
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Duchenne Muscular Dystrophy
Phase I/II Study of PRO044 in Duchenne Muscular Dystrophy (DMD)
The purpose of this study is to see whether PRO044 is safe and effective to use as medication for DMD patients with a mutation around location 44 in the DNA for the dystrophin protein.
- Trial name
- NCT01037309
- Testing
- PRO044 SC, PRO044 IV
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 18 people
- Sponsor
- BioMarin Pharmaceutical
Chronic Tendinopathy
Autologous Fat Grafting for the Treatment of Chronic Tendinopathy
The goal of this clinical trial is to learn whether a one-time injection of a person's own processed fat tissue (autologous lipoaspirate), a procedure called Adipose Stem/Stromal Cells for Enthesis/Tendon Therapy (ASSET), can…
- Trial name
- ASSET (NCT07748793)
- Testing
- Adipose Stem/Stromal Cells for Enthesis/Tendon Therapy (ASSET) Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Abdominal Compartment Syndrome, Pancreatitis,Acute Necrotizing
Fasciotens to Treat an Open Abdomen - a Prospective Cohort Study
The open abdomen can occur as a result of various diseases. After infections of the abdomen, compartment syndromes or traumata, it is essential for survival (1). This condition of the open abdomen lasts from days to months.
- Conditions
- Abdominal Compartment Syndrome, Pancreatitis,Acute Necrotizing, Intraabdominal Hypertension, Peritonitis
- Trial name
- Fasciotens (NCT04033614)
- Testing
- Fasciotens-Abdomen
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- RWTH Aachen University
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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