Clinical trials: Macular Edema, Cystoid
Pseudophakic Cystoid Macular Edema
Efficacy of Nonsteroidal Anti-Inflammatory Drugs for the Prevention of Cystoid Macular Edema Following Cataract Phacoemulsification
This randomized clinical study evaluated the effectiveness of different postoperative nonsteroidal anti-inflammatory drug (NSAID) regimens in patients undergoing uncomplicated phacoemulsification cataract surgery.
- Trial name
- NCT07696104
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Nepafenac 0.1% eyedrops, diclofenac 0.1% ophthalmic susp.
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Pomeranian Medical University Szczecin
Cystoid Macular Edema, Postoperative, Diabetes Mellitus
Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients
The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract…
- Trial name
- NCT02646072
- Testing
- Ketorolac tromethamine ophthalmic solution 0.45%
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Macular Edema, Retinal Vein Occlusion
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
A phase 2, multicenter, randomized, active-controlled, masked, parallel arm study designed to evaluate the safety and efficacy of a single suprachoroidal injection of CLS-TA, triamcinolone acetonide injectable suspension, given…
- Trial name
- TANZANITE (NCT02303184)
- Testing
- 4 mg CLS-TA, IVT aflibercept
- Where
- 14 sites in United States
- Volunteers
- 46 people
- Sponsor
- Clearside Biomedical, Inc.
Birdshot Chorioretinopathy, Cystoid Macular Edema
Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a
Birdshot Retine choroidopathy (BRC) is a sight threatening posterior uveitis. The long term visual outcome has recently be studied showing a legal blindness to 14% at 5 years.
- Conditions
- Birdshot Chorioretinopathy, Cystoid Macular Edema, Transient Partial Visual Loss
- Trial name
- BIRDFERON (NCT00508040)
- Testing
- interferon alpha 2a, prednisone
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), Descemet Membrane Endothelial Keratoplasty (DMEK)
DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)
The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients…
- Trial name
- DMEC (NCT05072262)
- Testing
- Nepafenac Ophthalmic, Dexamethasone Ophthalmic
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Cystoid Macular Edema Following Cataract Surgery, Bilateral
Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery
The purpose of this study is to compare effects of preoperative and postoperative use of topical ketorolac tromethamine 0.4% versus placebo in uncomplicated cataract surgery.
- Trial name
- NCT01542190
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Age Related Macular Degeneration, Diabetic Retinopathy
Effect of Video Viewing on Intravitreal Injection Experience
Study Objective The goal of this clinical trial is to evaluate whether viewing a procedural video can improve the patient experience and reduce the incidence and severity of subconjunctival hemorrhage in individuals undergoing…
- Conditions
- Age Related Macular Degeneration, Diabetic Retinopathy, Choroidal Neovascularization, Retinal Vein Occlusion
- Trial name
- NCT07002372
- Testing
- Procedure video viewing
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Macular Edema, Cystoid
Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling
Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for…
- Trial name
- NCT04472039
- Testing
- optical coherence tomography (OCT)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Diabetic Macular Edema
A Randomized, Placebo-Controlled Clinical Trial of Intravitreal Triamcinolone for Refractory Diabetic Macular Edema
To determine the efficacy and safety of intravitreal triamcinolone acetonide for refractory diabetic macular edema.
- Trial name
- NCT00369863
- Testing
- Triamcinolone acetonide
- Where
- Iran
- Volunteers
- 76 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Uveitis Related Cystoid Macular Edema
Functional and Morphologic Aspects of Intravitreal Triamcinolone for Uveitis-associated Cystoid Macular Edema
Purpose: To evaluate the effect of intravitreal triamcinolone acetonide (IVTA) on uveitis-associated cystoid macular edema (CME) using high resolution optical coherence tomography (SDOCT) in conjunction with thorough visual…
- Trial name
- NCT01299129
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Cataract, Glaucoma
Incidence of Sub-clinical Cystoid Macular Edema After Cataract Surgery
Cystoid macular edema (CME) can limit visual acuity after cataract surgery. Little is known whether the incidence is similar between standard ultrasound phacoemulsification cataract surgery (phaco), femtolaser assisted cataract…
- Trial name
- ICCME (NCT04161963)
- Testing
- SD-OCT, OCT-A
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Retinitis Pigmentosa, Cystoid Macular Edema
Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema
This study aims at investigating the therapeutic potential of recombinant human Nerve Growth Factor ( rhNGF ) eye drops treatment in patients with Retinitis Pigmentosa (RP) associated with cystoid macular edema (CME) in a phase…
- Trial name
- NEMO (NCT02609165)
- Testing
- rhNGF 180 µg/ml eye drops solution, vehicle eye drops
- Where
- 2 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Ospedale San Raffaele
Postoperative Cystoid Macular Edema, Irvine-Gass Syndrome
Study for Optimizing Anti-inflammatory Prophylaxis
The purpose of this study is to investigate which anti-inflammatory treatment is best at preventing postoperative inflammation following cataract surgery.
- Trial name
- SOAP (NCT03383328)
- Testing
- NSAID + prednisolone, preoperative, NSAID + prednisolone, postoperative, NSAID, preoperative
- Where
- Denmark
- Volunteers
- 470 people
- Sponsor
- Line Kessel
Cystoid Macular Edema, Uveitis
Vitamin E to Treat Uveitis-Associated Macular Edema
This study will evaluate whether vitamin E can help treat swelling of the macular area of the retina (the back part of the eye) associated with uveitis (inflammatory eye disease).
- Trial name
- NCT00021645
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Macular Edema, Cystoid, Retinal Vein Occlusion
The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study
The SCORE Study will compare the effectiveness and safety of standard care to intravitreal injection(s) of triamcinolone for treating macular edema (swelling of the central part of the retina) associated with central retinal vein…
- Trial name
- SCORE (NCT00105027)
- Testing
- Standard Care, intravitreal triamcinolone injection
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- The Emmes Company, LLC
Retinitis Pigmentosa, Cystoid Macular Edema
Intravitreal Dexamethasone Implant in Retinitis Pigmentosa-related Macular Edema- a Retrospective Study
Purpose: Cystoid macular edema (CME) in retinitis pigmentosa (RP) has been managed in several ways with little success. The aim of our study was to report the use of intravitreal dexamethasone implant in a large series of…
- Trial name
- NCT02804360
- Testing
- dexamethasone injection
- Volunteers
- 50 people
- Sponsor
- Rafic Hariri University Hospital
Macular Edema, Retinal Vein Occlusion
Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201
The purpose of this non interventional retrospective study is to continue to collect data from patients following their completion of Protocol CLS 1003-201: "Safety and Efficacy of Suprachoroidal CLS-TA with Intravitreal…
- Trial name
- NCT02956330
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Clearside Biomedical, Inc.
Cystoid Macular Edema
Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility…
- Trial name
- NCT00494494
- Testing
- Standard Care, nepafenac
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of North Carolina, Chapel Hill
Cystoid Macular Edema Following Cataract Surgery
PCME Prevention in Patients With NPDR
Pseudophakic cystoid macular edema (PCME), or Irvine-Gass syndrome, is retinal thickening of the macula, which usually develops within 3 months after surgery, with a peak incidence between 4 and 6 weeks.
- Trial name
- NCT04940338
- Testing
- Bromfenac Ophthalmic 0.09% Ophthalmic Solution, Dexamethasone Ophthalmic, Phacoemulsification surgery (PHACO)
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Cataract, Cystoid Macular Edema After Phacoemulsification
Effects of Bromfenac on Macular Thickness After Phacoemulsification Surgery
The goal of this clinical trial is to learn if bromfenac ophthalmic solution can prevent cystoid macular edema (CME) and reduce macular thickness in patients undergoing phacoemulsification surgery for cataract removal.
- Trial name
- NCT06785090
- Testing
- Bromfenac, Moxifloxacin 0.5% ophthalmic solution, Dexamethasone phosphate 0.1%
- Where
- Iraq
- Volunteers
- 87 people
- Sponsor
- Inas Abd