Clinical trials: Macular Hole Surgery
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Idiopathic Macular Hole
Indocyanine Green or Trypan Blue for Delamination of the Internal Limiting Membrane in Macular Hole Surgery
To evaluate the anatomical and visual outcomes after vitrectomy and internal limiting membrane (ILM) peeling with indocyanine green (ICG) or trypan blue (TB) for idiopathic macular hole repair in a prospective randomized trial.
- Trial name
- NCT00419185
- Testing
- Delamination of the Internal limiting membrane
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Luebeck
Retinal Perforations, Myopia, Degenerative
Corneal Flap Transplantation for Macular Hole Repair of High Myopia
The goal of this clinical trial is to learn about an innovative surgical technique for macular hole repair. This technique is for patients with high myopia using pars plana vitrectomy (PPV) combined with corneal flap…
- Trial name
- NCT05875909
- Testing
- corneal flap transplantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First People's Hospital of Hangzhou
Stage 2 or 3 Full Thickness Macular Hole
Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
A macular hole is a fairly common problem in the retina and is an important cause of loss of central vision. The aim of this study is to determine whether, in patients with a stage 2 or 3 full thickness macular hole (FTMH)…
- Trial name
- FILMS (NCT00286507)
- Testing
- Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
- Where
- 9 sites in Ireland, United Kingdom
- Volunteers
- 141 people
- Sponsor
- University of Aberdeen
Macular Holes
Comparative Analysis of Large Macular Hole Surgeries
This study compares the anatomical and visual outcomes in a large series of patients affected by idiopathic macular holes larger than 400 µm treated using pars plana vitrectomy and gas tamponade combined with internal limiting…
- Trial name
- CAOLMHS (NCT04116892)
- Testing
- the Cover group, the Fill group, the peeling group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Comparison of 3D Visualization and Microscope for VR Surgery
Damages From Macular Grasping During Vitrectomy Comparing Traditional and 3D Microscope
Randomized, prospective, descriptive and comparative clinical study. The comparison is between a group of patients affected by macular pucker or macular hole, whose macular peeling is performed using a traditional optical…
- Trial name
- NCT05113212
- Testing
- Macular surgery with NGENUITY surgical display system, Macular surgery with standard operating microscope
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Anna Rita Daniele, MD
Macular Hole, Epiretinal Membrane
Optical Coherence Tomography - Rescan During Dissection of Macular Membranes
In our study , the investigators will use the microscope with OCT ( Lumera with RESCAN OCT ) coupled to assess the extent , depth and change of retinal architecture in the perioperative period .
- Conditions
- Macular Hole, Epiretinal Membrane, Traction Syndrome Vitreomacular, Proliferative Vitreoretinopathy
- Trial name
- NCT02748421
- Testing
- Lumera Microscope with OCT RESCAN, Conventional Microscope
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Macular Holes, Vitrectomy
Postoperative Same Day Closure of Giant Macular Hole With Silicone Oil
Patients with stage 3 and 4 macular holes of size \>700 microns who underwent pars plana vitrectomy, Internal limiting Membrane peeling and silicone oil tamponade were followed at day 1 , 2 weeks and 1 month post silicone oil…
- Trial name
- GiantMH-SO (NCT06915948)
- Testing
- Macular Hole Surgery
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Ahalia Foundation Eye Hospital
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Macular Holes, Retinal Detachment
A Study of a New Surgical Treatment of Macular Hole Retinal Detachment in High Myopia
This study evaluates the surgical outcomes of inverted internal limiting membrane insertion combined with air tamponade in the treatment of macular hole retinal detachment (MHRD) in high myopia, and also to compare the treatment…
- Conditions
- Macular Holes, Retinal Detachment, High Myopia
- Trial name
- NCT03383731
- Testing
- Group 1, Group 2
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Full Thickness Macular Hole
Pilot Randomised Controlled Trial of Posturing Following Surgery for Full-thickness Macular Hole
This is a pilot randomised controlled trial (RCT) to investigate the effect of postoperative face-down positioning on the outcome of macular hole surgery.
- Trial name
- NCT01226160
- Testing
- Postoperative face-down posturing, Postoperative non-posturing group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Macular Hole
Outcomes of Macular Hole Surgery With Inverted Flap With vs Without Post op Posturing With SF6 in Macular Hole More Than 400 Micrometres
This study evaluated the outcomes of surgery for large full-thickness macular holes measuring more than 400 micrometres using the inverted internal limiting membrane flap technique with sulphur hexafluoride (SF6) gas tamponade.
- Trial name
- NCT07787390
- Testing
- Macular Hole Surgery With Inverted Internal Limiting Membrane Flap and SF6 Gas Tamponade, Face-Down Postoperative Positioning, No Face-Down Postoperative Positioning
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore General Hospital
Macular Holes, Epiretinal Membrane
Safety and Efficacy Evaluation of Two Different Brilliant Blue G Dyes as Staining Agent in Vitreo Retinal Surgery.
This is a prospective, Open-label, comparative clinical study to asses two brilliant blue G dyes as staining agent in Vitro Retinal Surgery.
- Trial name
- NCT05086588
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Idiopathic Macular Holes
Brillant Blue Versus Indocyanine Green for Macular Hole Surgery
Macular Hole Surgery with two different Dyes
- Trial name
- NCT00757471
- Testing
- Brillant Blue, Indocyanine Green
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Macular Holes, Retinal Detachment
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.
- Trial name
- NCT04535622
- Testing
- A structured exercise
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Macular Holes
Compare the Healing Process of Idiopathic Macular Hole With Different Surgical Techniques
To compare anatomic and functional results, and to evaluate postoperatively the healing process in 2 different techniques for the closure of the macular holes (MH)
- Trial name
- NCT03888625
- Testing
- Conventional ILM Peeling, Inverted ILM Peeling
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Macular Holes
Inverted ILM-flap Techniques Variants for Macular Hole Surgery: Outcomes Comparison
To report closure rate, Best Corrected Visual Acuity (BCVA), Retinal Sensitivity (RS) and Fixation Stability (FS) of idiopathic Macular Holes (MH) randomized to Cover Group (CG) or Fill Group (FG) of the Inverted Internal…
- Trial name
- NCT04135638
- Testing
- Cover Group, Fill Group
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- University of Molise
Macular Holes
Position Related Changes in Macular Hole Morphology Before and After Surgery
Macular hole is a full thickness retinal defect in the very centre of the retina that gives the sharpest vision. The condition causes a substantial deterioration of visual acuity, and operative measures are necessary in order to…
- Trial name
- NCT04676217
- Testing
- Postoperative positioning advice
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Macular Holes
Elongation of Foveal Tissue After Macular Hole Surgery
In our experience, elongation of foveal tissue after macular hole surgery which was undetectable by conventional time-domain optical coherence tomography was often observed on spectral-domain optical coherence tomography images.
- Trial name
- NCT01471912
- Testing
- pars plana vitrectomy and fluid gas exchange
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Samsung Medical Center
Macular Hole
An Objective Evaluation of Postoperative Positioning in Macular Hole Surgery
The macular hole formation takes place in the centre of the retina. A closure of the macular hole is believed to take place if the central retinal area is kept dry in the postoperative period.
- Trial name
- NCT02011165
- Testing
- Positioning measuring device
- Where
- 2 sites in Norway
- Volunteers
- 43 people
- Sponsor
- Helse Stavanger HF