Clinical trials: Macular Pigment Optical Density
Risk Factors for Age Related Macular Degeneration
Effects of Sea Buckthorn Oil and Lutein on Eye Health
Low macular pigment optical density has been associated with increased risk of age-related macular degeneration, an important cause of vision problems in the elderly population.
- Trial name
- SBEYE (NCT02379169)
- Testing
- Sea buckthorn oil & lutein
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Changes in Macular Pigment Optical Density
Regional Kale as Source of Lutein and Zeaxanthin to Improve Vision of AMD-patients
The age-related macular degeneration (AMD) is an age-dependent, multi-factorial disease. In Western industrial countries, it is the main cause of visual impairments. In Germany, approximately 4.5 million people suffer from AMD.
- Trial name
- KALESIGHT (NCT02136303)
- Testing
- S1: Dosage-dependency, S2: Kale extract versus kale purée, S3: Kale extract: AMD-patients
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jena
Macular Pigment Optical Density
Wenzhou Dry Age-related Macular Degeneration (AMD) Progression Study
To evaluate the correlation between macular pigment optical density (MPOD) levels and risk of progression in patients with age-related macular degeneration
- Trial name
- NCT03433885
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University
High Myopia
Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.
Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area. Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density.
- Trial name
- NCT02205632
- Testing
- MPS II
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Poitiers University Hospital
Glaucoma, Glaucoma, Angle-Closure
Macular Pigment Optical Density in Primary Angle-closure Disease
Glaucoma is the leading cause of irreversible blindness in the world, and primary angle-closure glaucoma (PACG) is the most important type of glaucoma in Asia.
- Conditions
- Glaucoma, Glaucoma, Angle-Closure, Macular Pigment Optical Density
- Trial name
- NCT05251792
- Testing
- Ocular examination
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cognitive Performance, Age-Related Macular Degeneration
Lutein, Zeaxathin, and Fish Oil Supplementation
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults.
- Conditions
- Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
- Trial name
- NCT06489873
- Testing
- Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Glaucoma, Glaucoma Eye
Augmented Macular Pigment-containing Nutraceutical and Central Visual Function
The purpose of this study is to prospectively analyze changes in macular pigment optical density and dermal carotenoid levels as they relate to visual field function in patients prescribed a macular pigment-containing medical…
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
- Trial name
- NCT04676126
- Testing
- Lumega-Z, Dorzolamide Hcl 2% Oph Soln
- Where
- United States
- Sponsor
- University of the Incarnate Word
Posterior Capsule Opacification, Retinal Degeneration
Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
It has been hypothesized that potential effects of laser Nd: YAG laser posterior capsulotomy may affect macular pigment as well as choroidal thickness, macular thickness and anterior chamber parameters, so it was aimed to…
- Conditions
- Posterior Capsule Opacification, Retinal Degeneration, Retinal Detachment, Anterior Chamber Angle Congestion
- Trial name
- NCT03321253
- Testing
- Nd: YAG laser posterior capsulotomy
- Volunteers
- 38 people
- Sponsor
- Afyon Kocatepe University Hospital
Macular Pigment Optical Density
"Visiobiane Anti-age" Effects on Vision Parameters
The purpose of this study is to determine the benefits of "Visiobiane Anti-age" dietary supplement on macular pigment optical density, contrast sensibility and visual acuity.
- Trial name
- NCT00449917
- Testing
- lutein, DHA, vitamins
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PiLeJe
Cognitive Function
Influence of Eggs on Cognitive Performance
This clinical trial aims to evaluate the nutrients in eggs in healthy adult's cognitive performance. The main questions it aims to answer are: How do the nutrients in eggs impact visual cognitive performance (VCP) in generally…
- Trial name
- NCT06465888
- Testing
- egg whites, whole eggs, Omega-3 eggs
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Age-related Macular Degeneration, Choroidal Neovascular Age-related Macular Degeneration
Association of Macular Pigment Optical Density (MPOD) and Genetic Variants in Complement Factor H in Subjects With Choroidal Neovascular (CNV)
Subjects with wet AMD, dry AMD, and age-matched controls will undergo routine occular measurements, will provide a blood and cheek cell sample, and will have macular pigment optical density (MPOD) measured to determine if there…
- Trial name
- NCT01682382
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sequenom, Inc.
Full Macular Hole
Changes InMPOD After Full-thickness Macular Hole Closure
The notable increase in MPOD following successful surgery suggests its potential role as a valuable adjunctive biomarker associated with a good visual prognosis following this type of macular hole surgical interventions.
- Trial name
- NCT06664515
- Testing
- Ciro Costagliola
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Federico II University
Age Related Macular Degeneration, Cognition Disorders
The Zeaxanthin and Visual Function Study
To evaluate if supplementation of zeaxanthin (with or without Lutein) is beneficial to patients with early and moderate Atrophic Age Related Macular Degeneration.
- Trial name
- ZVF (NCT00564902)
- Testing
- 3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Chrysantis, Inc.
Age-related Macular Degeneration
Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular Degeneration
This study is to investigate the protective effects of supplemental lutein and zeaxanthin on early age-related macular degeneration (AMD) patients in China.
- Trial name
- NCT01528605
- Testing
- low lutein, high lutein, lutein plus zeaxanthin
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Peking University
Presence of Retinal Fluid, Changes in Macular Pigment Optical Density
Aflibercept 8 mg for nAMD: Early Anatomical and Functional Changes
Neovascular age-related macular degeneration (nAMD) is one of the main causes of irreversible vision loss in older people worldwide.
- Trial name
- NCT07074054
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Age Related Macular Degeneration
Macular Pigment Optical Density in Healthy Subjects
The macular pigment (MP) in humans consists of the yellow, blue-absorbing carotenoids lutein and zeaxanthin, which are contained in vegetables and fruits.
- Trial name
- NCT00993330
- Where
- Austria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Diabetic Retinopathy, Retinal Degeneration
The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes
It has been hypothesized that thermal damage of laser pan-retinal photocoagulation may affect macular pigment as well as inner layer cells in the retina, so it was aimed to investigate possible effect of conventional laser…
- Conditions
- Diabetic Retinopathy, Retinal Degeneration, Macula Abnormality, Laser Burn of Retina
- Trial name
- NCT03150654
- Testing
- Laser pan-retinal photocoagulation
- Volunteers
- 36 people
- Sponsor
- Afyon Kocatepe University Hospital
Macular Teleangiectasia, Macular Pigment
MPOD in Macular Teleangiectasia Following Supplementation of Lutein and Zeaxanthin
Earlier investigations have detected low levels of macular pigment (MP) in the center of the fovea and a halo of MP at a higher eccentricity in persons with type 2 idiopathic juxtafoveal teleangiectasia (MACTEL)[Helb H-M, Charbel…
- Trial name
- MacTEL-Supp (NCT00568828)
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- The Lowy Medical Research Institute Limited
Age Related Macular Degeneration
Association of MPOD Values With Blue Light.
This study aims to investigate in healthy adults 18-65 years of age the association of electronic device blue light exposure and macular pigment optical density (MPOD) considering usual dietary intake of lutein and zeaxanthin…
- Trial name
- AMPBL19 (NCT04779398)
- Where
- Australia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Macular Pigment Optical Density
The Effect of Gojiberry Intake (Lycium Barbarium) on Macular Function
Objective: To evaluate the effects of goji berry intake for three months on macular pigment ocular density (MPOD) between 45 and 65 years old.
- Trial name
- NCT03983525
- Testing
- Goji berry, Lutein + zeaxanthin supplementation
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis