Clinical trials: Macular Thickness
Congenital Cataract
Analysis of Retinal Nerve Fiber Layer and Macular Thickness After Congenital Cataract Surgery
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the retinal nerve fiber layer.
- Trial name
- NCT03621579
- Testing
- cataract surgery
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Pregnancy, Retinal Nerve Fiber Layer Thickness
Retinal Nerve Fiber Layer and Macular Thickness Changes During Pregnancy
Purpose: Primary: to prospectively measure Retinal Nerve Fiber Layer (RNFL) and macular thickness changes during pregnancy by Optical coherence tomography Secondary: The effect of pregnancy abnormalities on RNFL and macular…
- Conditions
- Pregnancy, Retinal Nerve Fiber Layer Thickness, Macular Thickness
- Trial name
- NCT02154945
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Hydration Status, Macular Thickness
Hydration Status and Ocular Parameters Study
This study will examine how hydration status (drinking a large amount of water or avoiding water for a short period of time) affects the eye.
- Conditions
- Hydration Status, Macular Thickness, Ocular Biometry
- Trial name
- HYDRI-EYE (NCT07177131)
- Testing
- Relative Dehydration Protocol, Hyperhydration Protocol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ante Kreso
Nerve Fiber Bundle Defect
Relation Between Macular and RNFL Thickness Measurement and Quality Grading in OCT
The investigators will enroll and scan normal eyes of healthy individuals using the Spectralis OCT. Each scan is graded on a scale of 0-40, with 0 representing the lowest quality and 40 the best possible one.
- Trial name
- NCT02700750
- Testing
- OCT exam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Macular, Congenital Cataract
Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the macular development.
- Trial name
- NCT04077489
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- yin ying zhao
Epiretinal Membrane, Pseudophakic Cystoid Macular Edema
"Cataract Surgery in Eyes With Epiretinal Membrane"
The purpose of the study is to evaluate retinal thickness change and the occurrence of central structural retinal changes after uneventful small-incision cataract surgery in eyes with asymptomatic early stages of epiretinal…
- Conditions
- Epiretinal Membrane, Pseudophakic Cystoid Macular Edema, Irvine-Gass Syndrome, Cataract
- Trial name
- NCT03404323
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna
Optical Tomography
Relationship Between Macular Thickness Measurement and Signal Strength in Optical Coherence Tomography
Signal strength is a parameter introduced in analysis software version 4.0.1, of the OCT stratus, that combines SNR and uniformity of the signal within a scan The scale of signal strength ranges from 1 to 10, with 1 representing…
- Trial name
- NCT01115881
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Cystoid Macular Edema, Postoperative, Diabetes Mellitus
Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients
The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract…
- Trial name
- NCT02646072
- Testing
- Ketorolac tromethamine ophthalmic solution 0.45%
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Corneal Dystrophy, Macular Dystrophy
The Efficacy of Hyperemesis Gravidarum on Macular Thickness, Corneal Thickness and Intraocular Pressure in Pregnancy
Aim Physiological changes in intraocular pressure as well as in the cornea and macula may occur during pregnancy. In the literature, there are limited data on ocular findings in hyperemesis gravidarum.
- Conditions
- Corneal Dystrophy, Macular Dystrophy, Hyperemesis Gravidarum - Severe
- Trial name
- NCT05927740
- Testing
- Optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Batman Training and Research Hospital
Glaucoma Patient, Glaucoma Suspect Patient
The Performances of Spectral Domain Optical Coherence Tomography (OCT) for Distinguishing Glaucomatous Eyes
The purpose of this study is to evaluate performances of each parameters of spectral domain (Cirrus) optical coherence tomography for distinguishing between normal eyes, glaucoma suspect and glaucomatous eyes
- Conditions
- Glaucoma Patient, Glaucoma Suspect Patient, Normal Population, RNFL Thickness by Location
- Trial name
- cirrusOCT (NCT01067482)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Healthy, Myopia
Ocular Imaging With Spectral Domain Optical Coherence Tomography
The purpose of this study is to analyze macular retinal thickness and macular volume using the spectral domain - optical coherence tomography (SD-OCT) in normal eyes and in eyes with various ocular diseases.
- Conditions
- Healthy, Myopia, Hypermetropia
- Trial name
- NCT00926549
- Testing
- Spectral domain-OCT (Cirrus™ HD-OCT, Carl Zeiss Meditec AG)
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Macular Holes
Clinical Characteristics and Surgical Outcomes of Full-thickness Macular Hole Without Focal Vitreomacular Traction.
This multicenter, retrospective, observational comparative study. We occasionally encounter FTMHs in which PVD has not been achieved and VMT is absent.
- Trial name
- NCT06560710
- Testing
- vitrectimy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Marianna University School of Medicine
Retinal Evaluation in Patients With GDM.
EVALUATION OF THE MACULAR, PERIPAPILLARY NERVE FIBER LAYER AND CHOROID THICKNESS CHANGES IN THE GESTATIONAL DIABETES MELLITUS, HEALTHY PREGNANT AND WOMEN VOLUNTEERS.
Gestational diabetes mellitus (GDM) is a risk factor for the development of type II diabetes and it is responsible for the morbidity of both mother and child.
- Trial name
- NCT02035995
- Testing
- Pregnant volunteers with GDM
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Ophthalmopathy
Single Superior ILM/ERM Flap for the FTMH.
In this study, the investigators will make the only upper flap either from the internal limiting membrane or from the epiretinal membrane to cover the full thickness macular hole.
- Trial name
- NCT05494242
- Testing
- Surgical intervention
- Where
- Iraq
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Omer Othman Abdullah
Macular Edema, Macular Degeneration
Evaluation of the Retinal Health Monitoring System Thickness Module
Evaluate the ability and accuracy of the Retinal Health Monitoring System - Retinal Thickness Module (RHMS - RTM).
- Trial name
- NCT04499703
- Testing
- RHMS-RTM, SD-OCT
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Age-related Macular Degeneration
Effects of Sildenafil on Choroidal Thickness in AMD
Choroidal thinning has been hypothesized to partake in the pathogenesis of age-related macular degeneration (AMD), but it is not known if increasing choroidal thickness may potentially alter the disease course.
- Trial name
- NCT01830790
- Testing
- Sildenafil citrate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Multiple Sclerosis, Neuromyelitis Optica
Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Oct
The purpose of this study is to determine the ability of STRATUS OCT and high resolution OCT to detect and to quantify the neural loss in multiple sclerosis and neuromyelitis optica and its subtypes.
- Trial name
- NCT01024985
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cystoid Macular Edema Following Cataract Surgery
CME With Different Fluidic Parameters
Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on…
- Trial name
- NCT01385852
- Testing
- microcoaxial phacoemulsification
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Cornea Epithelial Mapping
CORNEAL EPITHELIAL MAPPING IN DIABETICS
The corneal epithelium is the outermost layer that covers the front of the eye; it not only functions as a barrier that blocks the passage of foreign material, but also plays an important role in maintaining high optical quality.
- Trial name
- NCT04734158
- Testing
- corneal imaging
- Where
- Egypt
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Minia University
Diabetic Macular Edema, Macular Edema, Cystoid
Effect of Intravitreal Long Acting Dexamethasone Implant, Ozurdex in Patients With Diabetic Macular Edema
This study is undertaken to determine the effect of intravitreal long acting dexamethasone implant,(Ozurdex®)in patients with diabetic macular edema.Diabetic macular edema is important cause of visual impairment in patients with…
- Conditions
- Diabetic Macular Edema, Macular Edema, Cystoid, Vision Disorders, Clinically Significant Macular Edema
- Trial name
- NCT01698749
- Testing
- long acting intravitreal dexamethasone implant
- Where
- India
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh