Clinical trials: Magnesium Sulphate
Neonates With HIE
Magnesium Sulfate in Neonatal HIE"
The study will investigates the neuroprotective effects of intravenous magnesium sulfate in neonates with hypoxic-ischemic encephalopathy (HIE) at a Karachi tertiary care hospital.
- Trial name
- NCT06342362
- Testing
- Magnesium sulfate
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Sindh Institute of Child Health and Neonatology
Fetal Neuroprotection
Magnesium Sulfate for Fetal Neuroprotection
Pregnant women diagnosed to have intrapartum fetal distress (Non reassuring or pathological changes according to NICE guidelines 2017) in any of the groups will receive the allocated treatment at least 20 minute before the…
- Trial name
- NCT04401852
- Testing
- MgSo4, Isotonic saline
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Organophosphate Poisoning
Magnesium Sulphate With Atropine and Pralidoxime vs Standard Therapy Alone in Acute Organophosphate Poisoning
Pakistan, being a developing country, is one of the regions with the most cases of organophosphate (OP) poisoning/toxicity. MgSO4 is one of the most promising adjunctive treatments that needs to be tested.
- Trial name
- NCT07777835
- Testing
- Atropine plus pralidoxime, Atropine and pralidoxime with adjunctive MgSO4
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Muhammad Aamir Latif
Laparoscopic Cholecystectomy
Adding Magnesium Sulfate to Bupivacaine in Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is one of the most commonly performed minimally invasive surgical procedures for the treatment of symptomatic cholelithiasis Laparoscopic cholecystectomy has clear benefits when compared with open…
- Trial name
- NCT05099250
- Testing
- Bupivacain, magnesium sulfate, saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Hysterectomy
Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate as Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : A Randomized Double-blinded Study
Over 80% of patients who undergo surgery suffer from acute postoperative pain, with 75% of them rating the pain severity as moderate, severe, or extreme.
- Trial name
- NCT06720337
- Testing
- bupivacaine 0.5%, Dexmedetomidine, MgSO4
- Volunteers
- 64 people
- Sponsor
- Assiut University
Post-spinal Shivering
Prophylactic Tramadol Versus Magnesium Sulphate for Prevention of Post-Spinal Shivering
This randomized controlled trial compared prophylactic intravenous tramadol and magnesium sulphate for the prevention of post-spinal shivering among women undergoing elective cesarean section under spinal anesthesia.
- Trial name
- TRAM-MAGS (NCT07838662)
- Testing
- Tramadol, Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Punjab Rangers Teaching Hospital Lahore
Severe Pre-eclampsia, Eclampsia
Comparison of Loading Dose Magnesium Sulphate With Prichard Regimen in the Management of Severe Preeclampsia and Eclampsia.
Preeclampsia/eclampsia is part of a spectrum of multi-systemic pregnancy disorder that contributes substantially to maternal and perinatal morbidity and mortality, especially in low resource setting.
- Trial name
- NCT06126068
- Testing
- Use of magnesium sulfate to prevent and stop fits in pre-eclampsia and Eclampsia
- Where
- Nigeria
- Volunteers
- 120 people
- Sponsor
- Federal Teaching Hospital Abakaliki
Peribulbar Anesthesia
Atracurium Versus Atracurium and Magnesium Sulphate As Adjuvants to Local Anesthetic
To evaluate the effects of adding magnesium sulfate to atracurium with local anesthetic mixture on akinesia of globe and eyelid regarding onset and duration in cataract surgery using peribulbar technique
- Trial name
- NCT06600945
- Testing
- Cataract surgery
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalia yousry Mohamed elsayed
Increased Intra Ocular Pressure (IOP)
The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation
The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non…
- Trial name
- NCT01241175
- Testing
- Magnesium Sulfate, normal saline
- Where
- Iran
- Sponsor
- Shiraz University of Medical Sciences
Upper Limb Injury
Adjuvants for Bupivacaine in Brachial Plexus Block in Pediatrics
Among paediatrics aging 3:12 who are going to have upper limb surgery,does adding clonidine to bupivacaine improve brachial plexus block outcome in comparison with magnesium sulfate with bupivacaine?
- Trial name
- NCT06180941
- Testing
- magnesium sulfate., clonidine.
- Volunteers
- 70 people
- Sponsor
- Assiut University
Radius Fracture
Magnesium Sulfate and Bupivacaine for Rehabilitation After Distal Radius Fractures
This study evaluates the effect of 10% magnesium sulfate in the rehabilitation of the wrist mobility in patients with distal radius fracture treated with percutaneous pinning and plaster
- Trial name
- NCT02514343
- Testing
- Magnesium Sulfate, Bupivacaine
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Post-tonsillectomy Pain, Tonsillectomy
Topical Magnesium Sulfate Versus Peritonsillar Bupivacaine for Post-Tonsillectomy Pain Relief in Children
Tonsillectomy (tonsil removal) is a very common surgery for children, but it often causes significant throat and ear pain afterward.
- Conditions
- Post-tonsillectomy Pain, Tonsillectomy, Postoperative Pain, Tonsillectomy Distress Syndrome
- Trial name
- NCT07760207
- Testing
- Magnesium Sulfate, Bupivacaine
- Volunteers
- 40 people
- Sponsor
- Assiut University
Asthma
Magnesium Trial in Acute Asthma in Emergency Department
Despite optimal initial emergency department (ED) therapy, 50% of children with severe acute asthma have ongoing moderate-severe respiratory distress.
- Trial name
- MAGICIAN (NCT06785272)
- Testing
- magnesium sulfate, Normal Saline
- Where
- 6 sites in Canada
- Volunteers
- 192 people
- Sponsor
- Suzanne Schuh
Postoperative Pain
Magnesium Sulfate for TAP Analgesia During Laparoscopic Cholecystectomy
Study the effect of adding Magnesium sulfate to TAP block in analgesia after laparoscopic cholecystectomy.
- Trial name
- NCT02533284
- Testing
- Magnesium Sulfate, bupevecaine, saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Pain, Postoperative
Pediatric Caudal Dexmedetomidine Enhances Postoperative Analgesia of Magnesium Sulphate in Lower Abdominal Surgeries
The study will conduct to compare the efficacy of Magnesium sulphate \& dexmedetomidine used as adjuvants to bupivacaine in caudal block to provide intra-operative anesthesia as well as post -operative analgesia in pediatric…
- Trial name
- JASayed (NCT02487355)
- Testing
- Dexmedetomidine, Magnesium Sulphate, Bupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Laparoscopic Cholecystectomy, Alleviate Postoperative Fatigue Syndrome
Esketamine Combined With Magnesium Sulfate for Postoperative Fatigue Syndrome in Patients Undergoing Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC), although minimally invasive, is frequently associated with postoperative fatigue syndrome (POFS), which can delay recovery and prolong convalescence.
- Trial name
- NCT07131033
- Testing
- Esketamine, Magnesium sulfate, Esketamine and Magnesium sulfate
- Where
- China
- Volunteers
- 128 people
- Sponsor
- The Second People's Hospital of Huai'an
Opioid Consumption, Multimodal Analgesia
Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy
Magnesium sulfate is one of the most commonly used co-analgetics. Its antinociceptive effect is related to antagonizing NMDA (N-methyl-D-aspartate) receptors of the nervous system, has an anti-inflammatory effect by reducing the…
- Conditions
- Opioid Consumption, Multimodal Analgesia, Acute Appendicitis, Complication of Treatment
- Trial name
- NCT06563349
- Testing
- Intravenous magnesium sulfate, Normal saline infusion
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Medical University of Warsaw
Smooth Extubation
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures.
- Trial name
- NCT04617652
- Testing
- Magnesium sulfate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Preeclampsia (PE)
Different Regimens of Magnesium Sulphate in Patients With Severe Preeclampsia
The goal of this observational study is to learn about the effects of the different drug regimens of magnesium sulphate in treatment of (severe pre-eclampsia).
- Trial name
- NCT06791668
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Ain Shams Maternity Hospital
Hypotension
Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries
General anesthesia organizes the best option for controlled blood pressure during rhinoplasty surgery. The primary agent applied in controlling hypotension should have particular unique characteristics.
- Trial name
- NCT05880693
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- mohamed