Clinical trials: Magnesium Sulphate
Threatened Preterm Labor
Nifedipine Versus Magnesium Sulfate for Late Preterm Tocolysis
Objective: This trial is designed to compare between the effectiveness of nifedipine versus magnesium sulfate (MgSO4) for tocolysis in women with threatened preterm labor.
- Trial name
- ASTOS2 (NCT05343806)
- Testing
- Nifedipine 20 Mg, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 264 people
- Sponsor
- Assiut University
Cerebral Palsy
Magnesium Sulphate for Preterm Birth (MASP Study)
The purpose of the study is to assess whether magnesium sulphate for women at risk of preterm birth can protect their children against cerebral palsy.
- Trial name
- MASP (NCT01492608)
- Testing
- Magnesium sulphate
- Where
- 14 sites in Denmark
- Volunteers
- 560 people
- Sponsor
- Hvidovre University Hospital
Asthma in Children
Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma
The purpose of study is to assess the effectiveness of nebulized magnesium sulphate in children presenting with acute asthma.Study perfoma consists of demographic variables,exclusion criteria and pediatric asthma score that…
- Trial name
- NCT04497766
- Testing
- Nebulized Magnesium sulfate, Intravenous magnesium sulphate
- Where
- Pakistan
- Volunteers
- 148 people
- Sponsor
- Saima Khatoon
Thrombotic Thrombocytopenic Purpura
Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care
Thrombotic Thrombocytopenic Purpura (TTP) is a potentially life-threatening thrombotic microangiopathy caused by a severe deficiency of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13).
- Trial name
- MAGMAT (NCT03237819)
- Testing
- Sulfate, Magnesium
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Pain Due to Trauma
Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture.
Prehospital management of traumatic pain is commonly based on morphine while loco-regional analgesia techniques, especially the femoral nerve block (FNB), can be safely and efficiently used.
- Trial name
- NCT03597945
- Testing
- lidocaine with epinephrine, normal saline, Magnesium sulfate
- Volunteers
- 48 people
- Sponsor
- Faculty of Medicine, Sousse
Atrial Fibrillation (AF), Magnesium Sulfate
Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
Atrial fibrillation (AF) is a common complication after cardiac surgery. Most studies suggest that the frequency ranges between 25-40%.
- Conditions
- Atrial Fibrillation (AF), Magnesium Sulfate, Post Cardiac Surgery Patients
- Trial name
- Magnesium AF (NCT06675500)
- Testing
- Magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Cough Suppression
Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sinus Surgery
Functional Endoscopic Sinus Surgery (FESS) is a widely performed procedure for the management of chronic rhinosinusitis and nasal polyposis.
- Trial name
- NCT07213037
- Testing
- Dexmedetomidine, Magnesium sulfate, lidocaine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rest Cramps
Exploring the Role of Magnesium in Rest Cramps
This study sets out to show whether infusions of magnesium can lessen the frequency of rest cramps and to determine whether rest cramp sufferers have a deficiency in magnesium.
- Trial name
- NCT00423540
- Testing
- Intravenous Infusion of Magnesium Sulfate
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hemodynamic Effect, Dexmedetomidine
Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia
This study aims to compare the hemodynamic effect of dexmedetomidine and magnesium sulphate as an adjuvant to lidocaine in preemptive peribulbar block in patients undergoing Dacryocystorhinostomy (DCR) under general anaesthesia…
- Conditions
- Hemodynamic Effect, Dexmedetomidine, Magnesium Sulphate, Lidocaine
- Trial name
- NCT07675616
- Testing
- Lidocaine + Dexmedetomidine, Lidocaine + Magnesium sulphate, Lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Sickle Cell Disease
Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis
The purpose of this study is to determine the safety and efficacy of intravenous magnesium in shortening the duration of a pain crisis and to determine the health-related quality of life and short term outcomes of children…
- Trial name
- MAGiC (NCT01197417)
- Testing
- Intravenous Magnesium Sulfate
- Where
- 8 sites in United States
- Volunteers
- 208 people
- Sponsor
- Medical College of Wisconsin
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cough
Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia
The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.
- Trial name
- MgSO4/DEX (NCT06979141)
- Testing
- Dexmedetomidine, Magnesium sulfate, Lidocaine
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Al-Azhar University
Post Operative Pain
Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia
This is a prospective randomized study that included 60 patients and was divided into two equal groups of patients who were scheduled for LC, Ages 18 and 60 years, both sexes, ASA I-II and BMI 19 - 39.
- Trial name
- NCT05281081
- Testing
- intraperitoneal levobupivacaine and morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
LMA Versus Mgso4 in Attenuating Stress Response During Emergence of Supratentorial Tumours Patients
A Comparative Study Between Laryngeal Mask Airway and Magensium Sulphate in Attenuating Systemic Stress Response During Emergence of Patients Undergoing Supratentorial Tumours.
To evaluate the efficacy of replacement of ETT with LMA and administration of Magnesium sulphate at the end of the surgery in attenuating systemic stress response during emergence of patients undergoing supratentorial tumours
- Trial name
- NCT03406403
- Testing
- Laryngeal mask airway, Magensium sulphate, Control group (closure of anesthetics)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Meningioma
Magnesium and Intraoperative Blood Loss in Meningioma Surgery
Meningioma is the most common central nervous system tumor and craniotomy with tumor removal was associated with moderate blood loss and blood transfusion.
- Trial name
- NCT03558516
- Testing
- Magnesium group, Normal saline group
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Lung Diseases
Adverse Events With Magnesium Sulfate
To investigate in pregnant women the adverse pulmonary effects of magnesium sulfate (MgSO4), a commonly used drug for tocolysis or arrest of labor.
- Trial name
- NCT00005448
- Where
- United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Mean Blood Pressure
Phentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative Study
The aim of this study is to evaluate the efficacy of controlled hypotensive anesthesia with phentolamine versus Magnesium sulfate in patients undergoing lumbar spine fusion surgery on blood loss, total dose of hypotensive agents…
- Trial name
- NCT04269980
- Testing
- MAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Preterm Birth, Periventricular Leukomalacia
Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth
Magnesium is neuroprotective in neonatal animal models of acquired hypoxic-ischemic and/or inflammatory cerebral lesions. It is associated with a significant reduction of perinatal death and cerebral palsy in some observational…
- Conditions
- Preterm Birth, Periventricular Leukomalacia, Brain Ischemia, Intracranial Hemorrhages
- Trial name
- NCT00120588
- Testing
- magnesium
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Rouen
ESPB, Mg Sulfate,Post Mastectomy
Efficacy of Magnesium Sulfate as an Adjuvant in Erector Spinae Plane Block as an Anesthetic Post Operative After Modified Radical Mastectomy
efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy
- Trial name
- NCT05976464
- Testing
- Magnesium sulfate in erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University