Clinical trials: Magnesium Sulphate
Spine Surgery
Effect of TIVA With Magnesium Sulfate on IONM in Patients Undergoing Spine Surgery
Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression.
- Trial name
- NCT04716439
- Testing
- Spine Surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Khalid University Hospital
Postoperative Pain
Intraoperative Magnesium Sulfate Administration During Orthotopic Liver Transplantation
The aim of study is to assess the effect of intraoperative use of magnesium sulfate in liver donating patients in reducing post-operative morphine requirements in early postoperative 24 hour in adult living liver donor.The…
- Trial name
- NCT03717467
- Testing
- isotonic saline, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Muscle Relaxation
Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to…
- Trial name
- MgSO4/MR (NCT05736744)
- Testing
- MgSO4, Cis-Atracurium
- Where
- 2 sites in Egypt
- Volunteers
- 58 people
- Sponsor
- Assiut University
Acute Ischemic Stroke
Intra-arterial Hypothermic Magnesium Sulfate Infusion in Combination with Endovascular Thrombectomy in Acute Ischemic Stroke
The primary objective of this study is to estimate the safety of intra-arterial hypothermic magnesium sulfate infusion after endovascular thrombectomy in patients with acute ischemic stroke
- Trial name
- Hypo-Mag (NCT06760195)
- Testing
- Intra-arterial hypothermic magnesium sulfate infusion, Endovascular thrombectomy, Intravenous thrombolysis
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Capital Medical University
Emergence From Anesthesia
Comparison Between Total Intravenous Anesthesia With Magnesium Sulphate Versus Total Intravenous Anesthesia With Dexmedetomidine in Patients Undergoing Lumbar Spine Surgeries
Although total intravenous anesthesia (TIVA) provides advantages such as accelerated recuperation and diminished postoperative nausea, it also has constraints, such as the potential for hemodynamic instability and inadequate…
- Trial name
- NCT07443163
- Testing
- Dexmedetomidine (Precedex®), magnesium sulfate
- Volunteers
- 40 people
- Sponsor
- Cairo University
Post Operative Pain
Addition of MgSO4 or Dexamethasone to Bupivacaine on the Prolongation of Ultrasound-guided Quadratus Lumboram Block
The goal of postoperative pain management is the provision of comfort, early mobilization and improved respiratory function without causing inadequate sedation and respiratory compromise, which can be achieved through using…
- Trial name
- NCT05397236
- Testing
- Bupivacaine- Magnesium, Bupivacaine dexamethasone, Bupivacaine saline
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Septic Shock, Sepsis
Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients
The goal of this clinical trial is to assess the effect of targeting upper normal serum magnesium levels on norepinephrine requirements in adult patients with septic shock. The main questions it aims to answer are: 1.
- Trial name
- NCT07716956
- Testing
- magnesium sulfate, standard care treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Atrial Fibrillation
Low Versus High Dose Magnesium Sulfate in the Early Management of Rapid Atrial Fibrillation
Objective: To assess the efficacy and the safety of high (9g) and low dose (4.5g) of MgS in the immediate treatment of rapid AF.
- Trial name
- NCT00965874
- Testing
- Magnesium Sulfate high dose, Magnesium Sulfate low dose
- Where
- Tunisia
- Volunteers
- 450 people
- Sponsor
- University of Monastir
Perineal Injury, Pain
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.
- Trial name
- NCT06393608
- Testing
- Epsom salt, Water
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antoine Roger
Post-ERCP Pancreatitis
Magnesium Sulfate in the Prevention of Post-ERCP Pancreatitis.
MagPEP is a multi-centre, randomized, phase III, double blind, placebo controlled, parallel group trial. It evaluates magnesium sulfate for the prevention of post-ERCP pancreatitis.
- Trial name
- MagPEP (NCT03749590)
- Testing
- Magnesium Sulfate
- Where
- Germany
- Volunteers
- 327 people
- Sponsor
- University Medicine Greifswald
Esophageal Spasm
Magnesium for Peroral Endoscopic Myotomy
Postoperative pain after peroral endoscopic myotomy occurs due to involuntary esophageal smooth muscle spasms. Magnesium has antispasmodic properties as a smooth muscle relaxant.
- Trial name
- MgPOEM (NCT04638881)
- Testing
- Magnesium sulfate, Normal Saline
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Stanford University
Chronic Obstructive Pulmonary Diseases
Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal
Chronic Obstructive Pulmonary Disease [COPD] is a major cause of chronic morbidity and mortality worldwide. COPD is characterized by persistent progressive airflow limitation that adversely affects the ventilation/perfusion (V/Q)…
- Trial name
- COPD (NCT03461328)
- Testing
- Magnesium Sulphate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Neuromuscular Block
Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
The magnesium sulfate and lidocaine have been increasingly used alone or in combination during anesthesia procedure to meet various objectives, such as reduction of pain, use of smaller anesthetic doses and stabilization of…
- Trial name
- NCT02483611
- Testing
- Magnesium Sulfate, Lidocaine, Isotonic Solution
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Abruptio Placentae
Magnesium Sulfate vs Placebo for Placental Abruption
To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.
- Trial name
- NCT00186069
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Postoperative Pain
The Effect of Intraoperative Magnesium Sulfate Infusion on the Postoperative Recovery
Evaluating analgesic effect of intraoperative magnesium sulfate infusion in the outpatient surgery case
- Trial name
- NCT03206008
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Persistent Fetal Circulation, Persistent Pulmonary Hypertension of the Newborn
Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn
The aim of this pilot randomized controlled blinded study is to evaluate the feasibility of using nebulized magnesium sulfate in the treatment of PPHN.
- Conditions
- Persistent Fetal Circulation, Persistent Pulmonary Hypertension of the Newborn, PPHN
- Trial name
- NebMag (NCT04328636)
- Testing
- Nebulized Magnesium Sulfate, Intravenous Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Sohag University
Mean Arterial Pressure
Low Dose Magnesium Sulphate
This clinical trial aims to compare Patients who receive propranolol 1-2 mg to Patients who receive propranolol 1-2 mg in addition to magnesium sulphate infusion 10 mg/kg to see if IV magnesium can stability mean arterial blood…
- Trial name
- NCT06621004
- Testing
- Patients will receive propranolol 1-2 mg., Patient receives magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Acute Ischemic Stroke
Intra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic Stroke
The goal of this Phase I unblinded, dose-escalation trial is to evaluate the safety and tolerability of intra-arterial magnesium sulfate injection after mechanical thrombectomy in patients experiencing acute ischemic stroke.
- Trial name
- NCT06956521
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Serratus Anterior Plain Block
SAP Block to Reduce Post Mastectomy Pain
To decrease post-operative pain in patients undergoing modified radical mastectomy.
- Trial name
- NCT03810209
- Testing
- Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University