Clinical trials: Magnesium Sulphate
Functional Endoscopic Sinus Surgery
Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
- Trial name
- NCT05442931
- Testing
- Pregabalin 150mg, Magnesium Sulfate, Nitroglycerin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Pediatric Burns
Magnesium Sulfate in Pediatric Burn Dressing Changes
Prospective feasibility trial utilizing adjuvant magnesium sulfate for analgesia/sedation during pediatric sedated burn dressing changes, which is ultimately hypothesized to decrease ketamine and/or sedative requirements.
- Trial name
- NCT07126795
- Testing
- magnesium sulfate, Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hennepin Healthcare Research Institute
Pain, Postoperative
Magnesium Sulfate Improves Postoperative Analgesia in Laparoscopic Gynecologic Surgeries
Magnesium sulfate has been reported to improve postoperative pain, but evidence is still controversial. Some studies demonstrated benefits while others concluded that there is no efficacy.
- Trial name
- Magnesium (NCT02508857)
- Testing
- Ketorolac, Magnesium, Saline solution
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Atrial Fibrillation New Onset
Peri-Operative Magnesium Infusion to Prevent Atrial Fibrillation Evaluated.
Post-operative atrial fibrillation (POAF) is commonly observed in patients post cardiac surgery without a previous history of atrial fibrillation (AF) or other arrythmias.
- Trial name
- POMPAE (NCT05669417)
- Testing
- Magnesium sulfate
- Where
- Netherlands
- Volunteers
- 265 people
- Sponsor
- HagaZiekenhuis
Cesarean Section; Shivering
Shivering Prevention During Cesarean Section by Intrathecal Injection of Magnesium Sulfate
Shivering is a common post-anesthetic complication occurring in up to 65% of patients undergoing spinal or epidural anesthesia. Shivering may interfere with electrocardiogram, blood pressure and oxygen saturation monitoring.
- Trial name
- NCT03008850
- Testing
- MgSo4
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Postoperative Pain
Magnesium Sulfate on Postoperative Pain
Breast cancer is the most diagnosed type of cancer in women in Turkey and in the world. According to the World Health Organization data, the rate of newly diagnosed breast cancer was reported as 11.6% in 20181.
- Trial name
- NCT05880732
- Testing
- Magnesium Sulfate, normal saline isotonic solution
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Postoperative Pain
Magnesium Sulfate for Analgesia in Pediatric Transplant
To use magnesium sulfate as adjuvant analgesia by implementing a treatment protocol in order to determine whether can benefit pediatric pain in post-operative transplanted patients and decrease overall opioid consumption.
- Trial name
- NCT04812028
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Minnesota
Postoperative Pain
TAP Block With Magnesium Sulfate Added to Local Anesthetic in Abdominal Hysterectomy
Major abdominal surgeries are associated with severe abdominal pain, which can affect respiratory and cardiac functions, if insufficiently managed. This increases the incidence of post-operative morbidity.
- Trial name
- NCT02930707
- Testing
- Magnesium Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Analgesia
Improving Quality of Bier Block
Intravenous regional anesthesia is one of the well-known techniques of regional anesthesia for short surgical operations on the upper and lower limbs. It was first introduced back in 1908.
- Trial name
- NCT04393610
- Testing
- Lidocaine, Magnesium Sulphate, Fentanyl
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
HIE
Beneficial Effect of Intravenous Magnesium Sulphate in Term Neonates With Hypoxic Ischemic Encephalopathy(HIE)
Neonatal mortality rate is the highest in Pakistan. And Birth Asphyxia is one of the main reversible causes. Outcomes related to birth asphyxia can be improved, if intervention done in time with proper measures.
- Trial name
- NCT04705142
- Testing
- MgSo4
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Abdominal Cancer, Abdominal Pain
Safety and Efficacy of Intrathecally Administered Magnesium Sulfate
Magnesium sulfate safety profile has been documented by histopathological analysis in experimental studies. magnesium sulfate added to local anesthetics decrease postoperative opioid requirements.
- Trial name
- NCT03459417
- Testing
- intrathecal morphine+LA, intrathecal morphine+LA+ Mg sulp. 50, intrathecal morphine+LA+ Mg sulp. 100
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Egypt Cancer Institute
Postpartum Hemorrhage
Effect of Magnesium Sulphate Pre-exposure on Oxytocin-induced Contractility in Desensitized Human Myometrium - an in Vitro Study
Postpartum hemorrhage (PPH) is the loss of more than 500ml of blood within 24 hours after delivery. It is a major cause of maternal morbidity and mortality across the globe.
- Trial name
- NCT02647268
- Testing
- Oxytocin, Magnesium Sulphate
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
TAP Block
Magnesium Sulphate Versus Dexamethasone as an Adjuvant to Bupivacaine in TAP Block for Abdominal Hysterectomy
The aim of this study is to compare the duration of analgesia obtained by addition of dexamethasone and MgSO4 as adjuvants to bupivacaine in TAP block in patients undergoing Total Abdominal Hysterectomy and to evaluate…
- Trial name
- NCT06166108
- Testing
- transversus abdominis plane (TAP) block in Abdominal hysterectomy
- Volunteers
- 56 people
- Sponsor
- Assiut University
Postoperative Complications
Comparing the Effect of Ketamine and Magnesium Sulfate Gargling With Placebo on Post-operative Sore Throat
A prospective randomized double-blind study including patients ASA I-II, aged more than 18 years undergoing surgery under general anesthesia (GA) and endotracheal intubation.
- Trial name
- NCT04705948
- Testing
- Magnesium sulfate versus ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Upper Limb Surgery, Brachial Plexus Blockade
Efficacy of Different Medications as Adjuvants in Ultrasound-guided Supraclavicular Brachial Plexus Block in Forearm Surgeries
This study is to evaluate whether addition of dexmedetomidine, dexamethasone and magnesium sulfate as adjuvants to bupivacaine in supraclavicular Brachial Plexus Blockade (BPB) for pain management assessed by VAS score.
- Trial name
- NCT06949488
- Testing
- Group A (DT): Dexmedetomidine group, Group B (MG): Magnesium group, Group C (DM): Dexamethasone group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Al-Azhar University
Hand, Foot and Mouth Disease
Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam
Hand foot and mouth disease (HFMD) is a common infectious disease caused by a number of different viruses - a small proportion of children infected with a particular type of enterovirus (EV71) develop neurological and systemic…
- Trial name
- NCT01940250
- Testing
- Magnesium Sulphate, Sterile water
- Where
- 2 sites in Vietnam
- Volunteers
- 26 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Analgesia
Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy Pain
Postoperative pain management is considered an integral part of perioperative care in patients undergoing thoracotomy. In order to reduce these complications, multiple regional techniques have been developed for thoracotomy…
- Trial name
- NCT05851768
- Testing
- Bupivacaine, Bupivacaine + Magnesium, Bupivacaine + Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Preeclampsia Severe, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter in Pre-Eclamptic Parturient Receiving Magnesium Sulfate Combined With Dexmedetomidine
Dexmedetomidine was reported to effectively reduce cerebral metabolism and ICP by decreasing cerebrospinal fluid pressure in patients with cerebral tumors or head injuries that require craniotomy.
- Trial name
- NCT05610774
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Preeclampsia With Severe Features
Use of Cheetah® Cardiac Monitoring System to Guide Discontinuation of Magnesium Sulfate in Women With Severe Preeclampsia
This is a single site pilot randomized, controlled, trial randomizing patients with PE with severe features to one of 2 groups: 24 hours of postpartum magnesium sulfate (current arbitrary standard of care) Using the Cheetah®…
- Trial name
- NCT04474704
- Testing
- Cheetah® non-invasive cardiac monitoring system, Standard of care
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Perinatal Anoxic-ischemic Brain Injury
Hypothermia Enhanced by Magnesium Sulphate
New 2010 neonatal resuscitation guidelines state that offering therapeutic hypothermia (TH) should be a standard of care in managing neonates with perinatal hypoxic - ischemic insult and present with signs of moderate and/or…
- Trial name
- Hemen (NCT02499393)
- Testing
- Magnesium Sulfate
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Polish Mother Memorial Hospital Research Institute