Clinical trials: Magnetic Resonance Imaging (MRI)
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Endothelial Dysfunction, Myocardial Perfusion Abnormalities
Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction
The goal of this research study is to demonstrate that Cardiac Perfusion MRI with Vasomotor Stress may serve as a non-invasive and less risky imaging technique for detecting non-obstructive perfusion deficits and/or abnormalities…
- Conditions
- Endothelial Dysfunction, Myocardial Perfusion Abnormalities, Cardiac MRI Perfusion With Vasomotor Stress, Diabetes
- Trial name
- NCT00808535
- Testing
- Cardiac Perfusion MRI w Vasomotor Stress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy, Nervous System Disease
Functional and Metabolic Imaging Using Magnetic Resonance Imaging and Spectroscopy
Technical advances in magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have provided researchers with the opportunity to study changes of the central nervous system (CNS) and improve diagnosis and…
- Trial name
- NCT00001591
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
Non-contrast Enhanced Cardiac Magnetic Resonance Normal Values and Imaging Protocols
One of the main problems in cardiac magnetic resonance (MR) investigations is the strong dependence of the achieved image quality on optimal settings of sequence parameters and anatomical and physiological situations and it is…
- Trial name
- CMR-TECH (NCT01728597)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Primary Dysmenorrhea
Evaluation of the Effect of TMS on Primary Dysmenorrhea
Based on the pain threshold and visual simulation score, primary dysmenorrhea patients will be divided into treatment effective group or non-effective group.According to the functional magnetic resonance imaging, the…
- Trial name
- NCT04168489
- Testing
- active rTMS
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Head and Neck Squamous Cell Carcinoma
Evaluation of OE-MRI in Patients With H&N Cancer
Assessment of the use of oxygen enhanced MRI scanning in a cohort of patients with head and neck squamous cell carcinomas to identify areas of hypoxia with tumours and relate this to treatment outcomes.
- Trial name
- NCT04724096
- Testing
- Oxygen Enhanced MRI scan
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Influence of Mouthpiece Design on Upper Airway Geometry
Evaluation With Scans and Pharyngometry of the Possible Changes in Upper Airway Geometry Induced by Using Different Mouthpieces.
In this study the possible changes in upper airway geometry induced by variations in the characteristics of the mouthpieces of inhalers will be evaluated with functional respiratory imaging (FRI) and Pharyngometry.
- Trial name
- NCT01592929
- Testing
- Magnetic Resonance imaging, Pharyngometry, Computed Tomography scan
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Carotid Artery Stenosis
Neuroimaging Correlates of Memory Decline Following Carotid Interventions
Carotid revascularization can significantly reduce the risk of stroke in patients with severe carotid stenosis; however, it has been associated with cognitive decline in 25% of the older adults who undergo the procedure.
- Trial name
- NCT02006095
- Testing
- Magnetic resonance imaging, Neuropsychological testing
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mood
The Effects of Cranial Electrotherapy Stimulation (CES) on Brain Function, Brain Chemistry and Mood
Document whether the Fischer Wallace Cranial Stimulator produces any measurable changes in brain activity.
- Trial name
- CES (NCT01860677)
- Testing
- Fisher Wallace Cranial Stimulator
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Cerebrovascular Circulation
Imaging Study to Compare Effects of Darolutamide and Enzalutamide With Respect to Placebo on the Blood Flow in the Brain in Healthy Male Volunteers.
The current study would investigate the effects of a single dose of darolutamide and enzalutamide compared with placebo and compared to each other on human brain blood flow using arterial spin labeling magnetic resonance imaging…
- Trial name
- NCT03704519
- Testing
- Darolutamide (BAY1841788), Enzalutamide
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bayer
Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease
Cambridge 7 Tesla Cerebral Small Vessel Disease Study
CamSVD is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. We aim to explore and understand the underlying arterial pathology in Cerebral Small Vessel Disease (SVD) using…
- Conditions
- Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease, Lacunar Stroke
- Trial name
- CamSVD (NCT04330222)
- Testing
- 7 Tesla Magnetic Resonance Imaging, Brief Memory and Executive Test
- Where
- United Kingdom
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Epilepsy
Mapping of the Epileptic Brain
This study aims improving the outcome after brain resective surgery of epileptic patients by improving presurgical evaluations. In particular the specific goal is to evaluate the ability of non invasive neuroimaging (functional…
- Trial name
- NCT00405145
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Familial Pancreatic Cancer, Pancreatic Adenocarcinoma
DCE MRI in Patients With Pancreatic Cancer
This clinical trial studies an imaging technique known as dynamic contrast enhanced magnetic resonance imaging (DCE MRI) in identifying the presence of pancreatic cancer.
- Conditions
- Familial Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreatic Intraductal Papillary-Mucinous Neoplasm
- Trial name
- NCT02070705
- Testing
- Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Ferumoxytol
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Pancreatic Cancer
Prediction of Surgical Resectability After FOLFIRINOX Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: the Role of Diffusion Weighted Magnetic Resonance Imaging, Radiomics and Liquid Biopsy (PeRFormanCe Trial)
In this prospective study, new diagnostic tools will be explored for patients with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (BR or LAPDA) who undergo neoadjuvant chemotherapy with FOLFIRINOX.
- Trial name
- PeRFormanCe (NCT05298722)
- Testing
- Imaging analysis of CT-scan and MRI with radiomics and genetic analysis of peripheral blood samples and questionnaires.
- Where
- 8 sites in Belgium, Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Obesity
MRI Based Study to Assess Brain-gut Axis in Obesity
The mechanism of neural communication between the brain and gut in the regulation of food intake is complex and not fully understood.
- Trial name
- BGImaging (NCT05437653)
- Testing
- Nutritional Drink A, Nutritional Drink B
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Uterine Fibroids, Pregnancy
Safety Trial of Magnetic Resonance (MR) Guided Focused Ultrasound Surgery (FUS) in Women With Uterine Fibroids Wishing to Pursue Pregnancy in the Future
The study objective is to develop data for the safety of pregnancies after thermal ablation of uterine fibroids by MR guided Focused Ultrasound using the Ex Ablate 2000 system.
- Trial name
- NCT00180739
- Testing
- Magnetic Resonance Guided Focused Ultrasound
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Essential Tremor, Tremor
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor (ET) is the most common tremor disorder, currently affecting an estimated 2.9 million Americans and leading to disability and decreased quality of life in 75% of cases.
- Trial name
- NCT02495883
- Testing
- Ethanol, Propranolol
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Radiculopathy Lumbar, MRI
Diffusion Tensor Sequences (DTI) for Study of Lumbar Roots by Magnetic Resonance Imaging (MRI)
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Radiculopathy Lumbar, MRI, Diffusion Tensor Imaging
- Trial name
- OPTI-DTI (NCT04224077)
- Testing
- Optimisation of DTI sequences
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Depression
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
- Trial name
- NCT00183677
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intertransverse Process Block, Thoracic Nerve Block
A Novel Intertransverse Plane Block: a Magnetic Resonance Imaging and Volunteer Study
Intertransverse process block (ITPB) is a thoracic nerve block technique where the LA is injected into the thoracic "intertransverse tissue complex" posterior to the superior costotransverse ligament (SCTL).
- Conditions
- Intertransverse Process Block, Thoracic Nerve Block, Thoracic Paravertebral Block
- Trial name
- NCT05538884
- Testing
- Intertransverse process block
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mahidol University
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