Clinical trials: Magnetic Resonance Imaging (MRI)
Relapsing-Remitting Multiple Sclerosis (RRMS)
MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)
This is a Phase 2 multicenter, double-blind, placebo-controlled, randomized, parallel-group trial to assess the efficacy and safety of 2 once-daily oral doses of IMU-838 (vidofludimus calcium), a small molecule inhibitor of…
- Trial name
- EMPhASIS (NCT03846219)
- Testing
- IMU-838 (30 mg/day), IMU-838 (45 mg/day), IMU-838 (10 mg/day)
- Where
- 38 sites in Bulgaria, Poland and 2 more
- Volunteers
- 210 people
- Sponsor
- Immunic AG
Cholecystitis; Acute, Choledocholithiasis
Early MRI in Acute GallstonE Disease
This pilot study aims to determine the utility of direct Magnetic Resonance Cholangiopancreatography (MRCP) in the assessment of suspected acute gallstone disease presentations.
- Trial name
- E-MAGED (NCT03709030)
- Testing
- magnetic resonance cholangiopancreatography (MRCP)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Perspectum
Autism Spectrum Disorder, Major Depressive Disorder
rTMS for Depression in Young Adults With Autism
The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD).
- Trial name
- rTMS-MDD (NCT04972136)
- Testing
- Active Bilateral Theta Burst Stimulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre for Addiction and Mental Health
Obesity
Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway
Identification of the cerebral fMRI phenotype of obese patients with FA in cognitive task context based on food choice making
- Trial name
- AddictO (NCT03454711)
- Testing
- fMRI, Indirect calorimetry, Bioimpedance
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Rennes University Hospital
Rectal Cancer, MRI
Predicting Locally Advanced Rectal Cancer Response to NCT and NCRT With MRI
This trial was designed to to study whether there is a difference in MRI image evaluation between NCRT and NCT, and try to build a model to predict the efficacy of neoadjuvant therapy by combining multiple imaging indexes.
- Trial name
- NCT04392609
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ziqiang Wang,MD
Ankle Injuries
Magnetic Resonance Imaging Evaluation of Lateral Ankle Instability
Lateral ankle instability may be acute or chronic. Acute instability usually occurs due to extreme rear foot supination with planter-flexion trauma leads to injury of lateral collateral ligament complex especially the anterior…
- Trial name
- NCT03695965
- Testing
- magnetic resonance imaging.
- Volunteers
- 30 people
- Sponsor
- Assiut University
Health
ANTERO-6 Cine-MRI Study
Previous research by TARGID (KU Leuven) has demonstrated the feasibility to assess gastric content volume by means of magnetic resonance imaging (MRI) while simultaneously evaluating gastric motor function by means of an…
- Trial name
- NCT04847765
- Testing
- VIPUN Gastric Monitoring System prototype
- Where
- Belgium
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Desaturation of Blood
Early Recognition of Hypoxia in Pediatric Patient Sedation
Early recognition of hypoxia through monitoring in sedation practices in pediatric patients
- Trial name
- NCT04622436
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Heart Failure and Reduced Ejection Fraction, Heart Failure
PRIMA-HF: Predicting Myocardial Recovery in Heart Failure Using Cardiac Imaging HAI-HF: High Dosing vs. Standard Dosing Adenosine During Myocardial Perfusion in Heart Failure
Background: Heart failure with reduced ejection fraction (HFrEF) is a heterogeneous condition with variable potential for left ventricular ejection fraction (LVEF) recovery.
- Trial name
- PRIMA-HF (NCT07243119)
- Testing
- HAI-HF: Adenosine Stress [¹⁵O]H₂O PET Imaging, Two different doses of adenosine
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Gødstrup Hospital
Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications
Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications
Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative…
- Conditions
- Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications, Donor Hepatectomy
- Trial name
- NCT07715500
- Testing
- Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Astrocytoma, Oligoastrocytoma
FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma
The aim of the study is to compare the two imaging modalities perfusion weighted MR-imaging and FET-PET in their ability to provide an accurate histological evaluation of low grade glioma and to reveal focal abnormalities within…
- Conditions
- Astrocytoma, Oligoastrocytoma, Oligodendroglioma
- Trial name
- NCT01089244
- Where
- 2 sites in Germany
- Volunteers
- 38 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Rectal Cancer
MRI-guided Lateral Lymph Node Dissection in Rectal Cancer
To investigate the oncological outcome of lateral lymph node dissection in low rectal cancer based on MRI
- Trial name
- NCT04850027
- Testing
- TME+Lateral lymph node dissection.
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology
Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)
This pilot study aims at evaluating the effectiveness of the treatment of unilateral or bilateral, non-pulsatile, disabling, tinnitus, without vestibular dysfunction, using Deep Brain Stimulation (DBS) of the parieto-insular…
- Conditions
- Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology, Resistant to Therapeutic Failure, With or Without Hearing Loss
- Trial name
- TINNOP3-DBS (NCT04296097)
- Testing
- DBS
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Grenoble
Prostate Cancer
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis
The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low.
- Trial name
- multiIMPROD2 (NCT04287088)
- Testing
- A shared decision making
- Where
- 4 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Healthy
Enteral Nutrition Infusion Rate and Gastric Function
A complex neurohumoral feedback mechanism regulates gastric emptying of enteral nutrition through changes in gastric motility. In this investigation, we aim to investigate the impact of different infusion rates of enteral…
- Trial name
- ANTERO-3 (NCT03664570)
- Testing
- VIPUN Balloon Catheter
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Prof Dr Jan Tack
Bladder Cancer
Validity of Computed Tomography Versus Magnetic Resonance Imaging in Predicting Muscular Invasion of Bladder Cancer
The aim of this work is to compare validity between CT and MRI in detecting muscular invasion in Patients with bladder cancer.
- Trial name
- NCT06046469
- Testing
- CT with contrast, MRI pelvis, TURBT
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Menoufia University
Parkinson
Impact of Exercise on Muscle Metabolism and Function for Persons With Parkinsons
This investigation assesses the impact of a strengthening program on muscle metabolism in the gastrocnemius muscle (GM) and is an essential step in the establishment of future clinical intervention for the GM in people with…
- Trial name
- NCT07720713
- Testing
- Home Exercise Program
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Central Nervous System Diseases
Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients
The purpose of this study is to determine if the contrast agent is effective and safe in the Magnetic Resonance Imaging (MRI) of brain or spine diseases in patients of Chinese origin.
- Trial name
- NCT00395460
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875), Magnevist
- Where
- 4 sites in China
- Volunteers
- 147 people
- Sponsor
- Bayer
Brain Injuries, Traumatic
Mild TBI Assessment & Rehabilitation
One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with mild TBI and comorbid conditions.
- Trial name
- MTAR (NCT02920788)
- Testing
- Goal-Oriented Attentional Self-Regulation (GOALS), Brain Health Education (BHE), fMRI
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Central Nervous System Diseases, Central Nervous System Neoplasms
Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs
Safety and Efficacy Study in pediatric subjects <2 years of age who have undergone Brain or Spine MRI pre and post 0.1 mmol/kg ProHance administration. Imaging conditions will represent those in routine clinical practice.
- Trial name
- NCT03750188
- Testing
- ProHance
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Bracco Diagnostics, Inc
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