Clinical trials: Magnetic Resonance Imaging (MRI)
Healthy, Obesity
New Heart Imaging Techniques to Evaluate Possible Heart Disease
Background: Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness.
- Conditions
- Healthy, Obesity, Diabetes, Healthy Volunteers
- Trial name
- NCT01399385
- Testing
- MR Imaging Techniques - 1, MR Imaging Techniques - 2, MR Imaging Techniques - 3
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prostate Carcinoma
Magnetic Resonance Whole Body Diffusion-Weighted Imaging in Finding Bone or Lymph Node Metastasis in Participants With High-Risk Prostate Cancer
This trial studies how well magnetic resonance whole body diffusion-weighted imaging works in finding cancer that has spread to the bone or lymph nodes (metastasis) in participants with high-risk prostate cancer.
- Trial name
- NCT03085043
- Testing
- Bone Scan, Computed Tomography, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- M.D. Anderson Cancer Center
Acquired Immunodeficiency Syndrome, Lipodystrophy
Proton Magnetic Resonance Spectroscopy (1H MRS) in Evaluating the Bone Marrow, Muscle and Adipose Tissue on Normal and Human Immunodeficiency Virus Infected Subjects
Magnetic resonance spectroscopy (MRS) is commonly applied in medicine with 1H proton or 31-phosphorus spectra. The proton MRS is often used in evaluating the central nervous system and 31P MRS is used in muscular diseases or…
- Trial name
- NCT00172315
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lumbar Fusion, Lumbar Spinal Fusion Surgery
Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery
Lumbar fusion has been widely used for spinal disorders when conservative treatment has failed. However, a number of studies have reported that the rate of re-operation is high for lumbar fusion surgery.
- Trial name
- NCT01703338
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Left Ventriclar Mass
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
Cardiovascular disease is the most common cause of death in the world. Most of the attention in treating ischemic heart disease (IHD) is understandably directed toward treating coronary artery disease.
- Trial name
- NCT01879293
- Testing
- Metformin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
Liver Cirrhosis, Liver Steatosis
EXplanted LIver and Ex-vivo Pancreatic Specimen Evaluation by 7 TESLA MRI
Aim of this study is to evaluate the correlation between the characteristics detected by the 7T MRI equipment and the histological composition of native explanted livers (group A), liver graft excluded for donation (group B) and…
- Conditions
- Liver Cirrhosis, Liver Steatosis, Hepatocellular Carcinoma, Pancreatic Cancer
- Trial name
- EXLIPSE (NCT04012021)
- Testing
- 7T Magnetic Resonance Imaging
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pisa
Breast Cancer
Quantitative Methods for Supplementing Contrast-Enhanced Magnetic Resonance Imaging of Breast Cancer
Contrast-enhanced magnetic resonance imaging (CE-MRI) is now established as the most accurate non-invasive imaging modality for characterizing breast cancer.
- Trial name
- NCT02058758
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
ST Segment Elevation Myocardial Infarction
Early Prediction of QFR in STEMI-Pharmaco-invasice
The study intends to provide important data on whether the noval method using quantitative flow ratio could predict microvascular dysfunction.
- Trial name
- EARLYmyoQFR-PI (NCT04220736)
- Testing
- Computation of quantitative flow ratio
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Attention Control, Healthy Volunteers
Attentional Control
The project is dedicated to understanding the integration within the brain of signals of different natures that contribute to attentional control.
- Trial name
- MACBRAIN (NCT03872999)
- Testing
- Functional brain imaging without any contrast agent
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Obesity, Type 2 Diabetes
The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics
This is a prospective, randomized, open-label, active drug controlled clinical trial that aims to compare the effects of henagliflozin or metformin on myocardial tissue level characteristics in type 2 diabetes patients with…
- Conditions
- Obesity, Type 2 Diabetes, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis
- Trial name
- NCT06059287
- Testing
- Henagliflozin, Metformin
- Volunteers
- 64 people
- Sponsor
- RenJi Hospital
Migraine, Epilepsy
High-field MR Imaging in Migraine, Visual Snow and Epilepsy
In this project, the aim is to recruit patients with drug resistant epilepsy and those suffering from migraine. Interestingly, patients suffering from epilepsy are also more often reporting to suffer from migraine.
- Conditions
- Migraine, Epilepsy, Visual Snow Syndrome
- Trial name
- NCT05524493
- Testing
- Structural MRI, Quantitative MRI, Diffusion MRI
- Where
- 2 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Inflammatory Bowel Diseases
Association Between Functional Changes in the Brain and the Perception of Pain in Patients With Inflammatory Bowel Diseases (IBD) - Measured With Functional Magnetic Resonance Imaging.
In the study the investigators aim to test whether transcranial direct current stimulation (tDCS)-induced pain reduction is in association with functional changes in the brain measured with functional magnetic resonance imaging…
- Trial name
- NCT03348852
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer
New Techniques to evAlUate Response to neOadjuvant Treatments in bReast cAncer (AURORA)
The role of neoadjuvant chemotherapy (NAC) in breast cancer is well established. Increasing rates of pathologic complete response (pCR) has increased de-escalation of surgical techniques.
- Trial name
- AURORA (NCT04795349)
- Testing
- Vacuum-assisted breast biopsy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Mechanical Low Back Pain
MRI-Based Structural Changes in Lumber Spine in Subjects With Discogenic Low Back Pain After Mckenzie Exercises.
In the rehabilitation department, we are working with patients of low back pain for routine management and as well as for research.
- Trial name
- NCT05673616
- Testing
- Mckenzie Extension Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Transcranial Random Noise Stimulation in Food Addiction Treatment
Obesity is worldwide a public health problem. According to World Health Organization (WHO), overweight and obesity are the fifth death risk factor worldwide. At least 2.8 million adults die each year.
- Trial name
- tRNS-FA (NCT02717247)
- Testing
- Active tRNS
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Hôpital le Vinatier
Multiple Sclerosis
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
This study will determine whether magnetic resonance imaging (MRI) can detect damage to certain parts of the brain and analyze the thickness of the brain's outer surface in patients with multiple sclerosis.
- Trial name
- NCT00099307
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
High-resolution Magnetic Resonance Imaging; Disorders of Consciousness
The Usage of High-resolution Magnetic Resonance Imaging in Patients With Disorders of Consciousness for Early Diagnosis
In this study, high-resolution brain functional magnetic resonance imaging (MRI) was used to evaluate the differences in brain structure and brain function network between patients with different degrees of disturbance of…
- Trial name
- NCT03475511
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Inguinal Hernia
MR Imaging of the 3D Inguinal Hernia Scaffold ProFlor
Demonstrating through MRI sequuences the regenerative features of the 3D inguinal hernia scaffold ProFlor
- Trial name
- NCT04762264
- Testing
- ProFlor inguinal hernia device
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Rectal Cancer Stage II, Rectal Cancer Stage III
Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer
Rectal cancer patients who received neoadjuvant chemoradiotherapy in Peking University Third Hospital in 2021 are divided into acute myelosuppression group, chronic myelosuppression group and normal group.
- Trial name
- NCT04970498
- Testing
- MRI, blood routine test
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Endometriosis
Quinagolide Vaginal Ring on Lesion Reduction Assessed by MRI in Women With Endometriosis/Adenomyosis
This will be a randomized, double-blind, placebo-controlled, proof-of-mechanism phase 2 trial investigating the effect of quinagolide extended-release vaginal ring on reduction of lesions assessed by high-resolution magnetic…
- Trial name
- QLARITY (NCT03749109)
- Testing
- Quinagolide 1080 µg
- Where
- 11 sites in Denmark, Germany and 2 more
- Volunteers
- 67 people
- Sponsor
- Ferring Pharmaceuticals
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