Clinical trials: Magnetic Resonance Imaging (MRI)
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Brain Diseases, Covid19
Pilot Study for PET/MR Imaging of Covid-19
The primary goal of this project is to study the feasibility of a prototype brain-dedicated PET insert for an MR scanner for simultaneous acquisition of PET/MR images of metabolism and perfusion in Covid-19 negative and…
- Trial name
- NCT04954248
- Testing
- Injected radiotracer with PET Insert
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ischemic Stroke, Transient Ischemic Attack
Intracranial Artery Stenosis Magnetic Resonance Imaging: Aetiology and Progression
Stroke has become the leading cause of death in China. It has been shown that intracranial artery stenosis (ICAS) plays a key role in Chinese stroke patients.
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Intracranial Artery Stenosis
- Trial name
- NCT03417063
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tsinghua University
Hepatitis C
Cognitive Impairments in Chronic Hepatitis C Patients and Potential Reversibility With New Agents (CICHepC)
The overall aim of this study is to evaluate the prevalence of cognitive impairments and brain anomalies in Chronic Hepatitis C infected individuals and to investigate likely changes in cognition and brain structure and function…
- Trial name
- CICHepC (NCT02745132)
- Testing
- Neuropsychological evaluation and Brain MRI
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Major Depressive Disorder
Multimodal MRI Characteristics of Psychotherapy Response in Late Life Depression
The specific focus of this study is to gather data regarding the effects of a psychological therapy known as Problem Solving Therapy (PST) on cerebral blood flow (CBF), cortical gray matter (GM) atrophy, subcortical white matter…
- Trial name
- PRS (NCT02440815)
- Testing
- Problem Solving Therapy
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight and Obesity
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
The purpose of this study is to determine how different behavioral interventions designed to alter food perceptions and behaviors affect brain responses to food, eating behaviors, and body weight.
- Trial name
- NCT05107908
- Testing
- Active Implicit Priming, Control Implicit Priming, Food Exposure Task
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aortic Stenosis
CMR-AI and Outcomes in AS
Background \& Aims: Artificial Intelligence (AI) in cardiac magnetic resonance (CMR) imaging has previously been shown to provide highly reproducible and accurate measures of myocardial structure and function, outperforming…
- Trial name
- NCT06128876
- Where
- 7 sites in Austria, Belgium and 4 more
- Volunteers
- 1,500 people
- Sponsor
- Medical University of Vienna
Hypertrophic Cardiomyopathy (HCM)
One-stop Evaluation of Hypertrophic Cardiomyopathy in Cardiac Magnetic Resonance
This is a multi-center, observational study aiming to establish a precision diagnosis scheme and multi-dimensional risk prediction models for Hypertrophic Cardiomyopathy (HCM). The study plans to enroll 10000 adult HCM patients.
- Trial name
- NCT07336290
- Volunteers
- 10,000 people
- Sponsor
- Minjie Lu
Liver Cirrhosis, Liver Fibrosis
Functional MRI to Determine Severity of Cirrhosis
This is a pilot study to investigate the feasibility of a novel MRI technique to assess the severity of liver cirrhosis and predict complications based on functionality and perfusion measurements whilst maintaining image quality.
- Trial name
- NCT03623360
- Testing
- Free breathing DCE-MRI
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leeds
Healthy Adult Participants
Global Reference Ranges - Mexico
The investigators aim to undertake the Global Reference Range Study (GRR) to establish a set of healthy adult reference values for measures of fibroinflammation, fat and size/volumes for the liver, and other abdominal and…
- Trial name
- GRR Mexico (NCT07664982)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Perspectum
Osteoporosis, Fractures, Compression
Dynamic Magnetic Resonance (MR) Study in Evaluating the Vertebral Bone Marrow Perfusion and Its Related Research
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood.
- Trial name
- NCT00172224
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney
Lowering Uric Acid in Live Kidney Donors
Recently there was described an increase in left ventricular mass after kidney donation. It is uncertain whether this is reversible or not.
- Trial name
- AL-DON (NCT03353298)
- Testing
- Allopurinol 300 mg
- Where
- Norway
- Volunteers
- 71 people
- Sponsor
- Oslo University Hospital
Healthy
The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy
The purpose of this research study is to determine whether brain anatomy impacts the efficacy of transcranial magnetic stimulation (TMS) which is a form of non-invasive brain stimulation.
- Trial name
- NCT04586387
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Crohn Disease (CD)
WAter Preparation in Crohn's Disease's Imagery
The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's…
- Trial name
- WAM (NCT06690632)
- Testing
- water preparation, polyethylene glycol preparation
- Where
- France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Toulouse
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy, Abnormal Vascular Flow
Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers
Racemic ketamine and S-ketamine are used in clinical practice today. Little is known of their difference in effect on cerebral blood flow, volume and metabolism.
- Trial name
- NCT01506921
- Testing
- Racemic ketamine, S-ketamine
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lund University
Heart Failure, Left Ventricular Systolic Dysfunction
Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.
Contemporary heart failure (HF) guidelines recommend insertion of a primary prevention implantable defibrillator (ICD) in patients with left ventricular ejection fraction less than 35% (LVEF < 35%) on maximally tolerated medical…
- Trial name
- CMR_GUIDE (NCT01918215)
- Testing
- ICD, ILR
- Where
- 18 sites in Australia, Germany and 1 more
- Volunteers
- 453 people
- Sponsor
- Flinders University
Non Mass Breast Lesions
Diagnostic Accuracy of Multiparametric Dynamic Contrast Enhanced Magnetic Resonance Imaging in Improving Detection of Ultrasound Non-mass Breast Lesions According to ACR BI-RADS v2025
this study aims To evaluate the diagnostic performance of Ultrasound (US) in correlation with Dynamic Magnetic Resonance Imaging (MRI) for the assessment, characterization, and evaluation of non-mass breast lesions.
- Trial name
- NCT07679308
- Testing
- multiparametric DCE- MRI and US for all patients
- Volunteers
- 60 people
- Sponsor
- Sohag University
Choledocholithiasis
To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
A Recent Meta analysis, showed pooled sensitivity and specificity were 97% and 90 for EUS and 87% and 92 for MRCP . This meta analysis includes only 5 studies, smaller sample size in each study, significant heterogeneity in…
- Trial name
- NCT04173624
- Testing
- Endosonography, Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Malignant Breast Tissue Neoplasm
Is Dietary Nitrate Effective in Reducing Aerobic Glycolysis in Breast Cancer?
Breast cancer is the most prevalent cancer affecting women, with 1 in 8 women in the UK developing breast cancer in their life time.
- Trial name
- BEET (NCT03944226)
- Testing
- Beetroot juice
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Aberdeen
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