Clinical trials: Magnetic Resonance Imaging (MRI)
Healthy
Evaluation of Leg Muscular Activity Using MRI and 11C-acetate PET/MRI. Pilot Study
The present study is conceived as a pilot study aimed to determine the efficiency of the newly available Positron Emission Tomography (PET) - Magnetic Resonance Imaging (MRI) hybrid scan technique for muscular activity…
- Trial name
- NCT02969603
- Testing
- Magnetic Resonance Imaging, Magnetic Resonance combined with Positron Emission Tomography
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Osman Ratib
Malignant Brain Tumors
(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors
PSMA is a transmembrane protein specifically expressed in the vascular endothelium of malignant brain tumors, most notably glioblastoma and not in healthy brain parenchyma.
- Trial name
- NCT05798273
- Testing
- intra-arterial injection, synchronous PET/MRI scan, Radiopharmacon Contrast agent
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Erasmus Medical Center
Magnetic Resonance Imaging, Cervical Spine Disease
7 Tesla MRI Evaluation of the Spine
High-resolution MRI (7 Tesla) of the spine is capable to differentiate osseous spurs from discus-material and better depict the compressed nerve in the neuroforamen compared to 3T MRI.
- Trial name
- NCT04441554
- Testing
- 7 Tesla MRI
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Reto Sutter, MD
Myocarditis, Takotsubo Cardiomyopathy
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)
Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues.
- Conditions
- Myocarditis, Takotsubo Cardiomyopathy, Reversible Coronary Ischaemia
- Trial name
- MEMORY (NCT04623788)
- Testing
- Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Substance Use, Healthy
Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model
This study seeks to understand individual differences in personality, brain function, and behavior. Study hypothesis: A stronger sign-tracking bias will be associated with a bottom-up processing style characterized by less…
- Trial name
- SIGN (NCT07094061)
- Testing
- fMRI, Questionnaires and surveys, Behavioral tasks and eye tracking
- Where
- 2 sites in United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Breast Neoplasms
Proton Magnetic Resonance Spectroscopy of Normal Breast Tissues in Women Volunteers
Magnetic resonance spectroscopy (MRS) is a diagnostic technique in MRI that distinguishes various metabolites on the basis of their slightly different chemical shifts or resonance frequencies.
- Trial name
- NCT00155090
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Post-Traumatic Stress Disorders, Brain Injuries
Identifying Biomarkers That Distinguish PTSD and mTBI Using Advanced Magnetic Resonance Spectroscopy
The purpose of this study is to develop a new test to help diagnose mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) in soldiers.
- Trial name
- NCT02927288
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Autism, Asperger's Syndrome
Functional Magnetic Resonance Imaging (fMRI) for the Study of Response Inhibition, and Face and Linguistic Processing in Autism
This study investigates face processing, response inhibition and phoneme processing in autistic adults by fMRI.
- Trial name
- NCT00211783
- Testing
- fMRI
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mediastinal Tumor
Assessment of Mediastinal Masses With Diffusion Weighted MR Imaging
Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy which is essential for treatment planning as well as for prognosis
- Trial name
- NCT03214341
- Testing
- MRI diffusion
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Assiut University
Dialysis, Excess Interdialytic Weight Gain
Haemodialysis fMRI Salt Appetite Study
1. Assessing how the rapid removal of salt and water by haemodialysis alters regional brain activity (by measurement of the brain blood oxygen level-dependent (BOLD) signal using functional MRI) during tasting of soup of…
- Trial name
- HeMSA (NCT04011254)
- Testing
- haemodialysis
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Heart Diseases, Ischemic
PET-MR Imaging of Coronary Atherothrombosis
Heart attacks remain a common cause of death throughout the world. The most common initiating event is the formation of a blood clot within the coronary arteries occluding blood supply to the heart.
- Trial name
- NCT03618303
- Testing
- PET-MRI scan
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Edinburgh
Coronary Heart Disease
Exercise and Brain in Coronary Heart Disease
The Heart-Brain project is a randomized controlled trial designed to examine the effects of two different exercise programs of 12-week duration: 1) aerobic high intensity interval training (HIIT), and 2) aerobic HIIT plus…
- Trial name
- Heart-Brain (NCT06214624)
- Testing
- Two types of exercise interventions
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Universidad de Granada
Cardiomyopathy, Congenital Heart Disease
Technical Development of Cardiovascular Magnetic Resonance Imaging
This study will explore new ways of using magnetic resonance imaging (MRI) to evaluate the heart and blood vessels of patients with cardiovascular disease, including better detection of myocardial infarction (heart attack) and…
- Conditions
- Cardiomyopathy, Congenital Heart Disease, Cardiovascular Disease, Cardiac Magnetic Resonance Imaging
- Trial name
- NCT00027170
- Testing
- Siemens MRI scanner
- Where
- 2 sites in United States
- Volunteers
- 8,781 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Prostate Cancer Diagnosis
PROVIZ - a Machine Learning Software, to Support Targeting of Prostate Biopsies on MR Images in Biopsy-naive Patients
To perform a traditional feasibility clinical investigation, as defined in ISO 14155:2020, to investigate preliminary feasibility, safety, and clinical performance information of a near-final design of the investigational…
- Trial name
- NCT06000046
- Testing
- Automatic image analysis
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian University of Science and Technology
Muscular Diseases, Spinal Muscular Atrophy
Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)
This study aims to refine the capability of Multispectral Optoacoustic Tomography (MSOT) and Magnet Resonance Imaging (MRI) to characterise the molecular composition of muscle tissue non-invasively and to evaluate the therapeutic…
- Trial name
- NCT04262570
- Testing
- Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Understanding Magnetic Resonance Imaging in Multiple Sclerosis
Magnetic resonance imaging (MRI) results play a major role in the lives of people with multiple sclerosis (pwMS). Even though MRI is used for diagnosis, prognosis and therapy control, pwMS' knowledge concerning this complex…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Clinically Isolated Syndrome
- Trial name
- UMIMS (NCT03872583)
- Testing
- Understanding MRI in MS (website), Control website
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Brain Tumor, Glioblastoma
Measuring Non-Enhancing Glioblastoma Progression
The goal of this clinical research study is to learn if magnetic resonance imaging with magnetic resonance spectroscopy ("MRI/MRS" scanning) can measure any extra growth in the tumor that does not show up on regular MRI images.
- Trial name
- NCT00777686
- Testing
- MRI/MRS Scan
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center
Cardiotoxicity, Elderly
Cardiotoxicity in the Elderly
CARTIER (Cardiotoxicity in the elderly) is a prospective cohort study of newly diagnosed elderly cancer patients equal or greater than 65 years of age conduced in one tertiary center (Hospital Universitario de Salamanca at Spain.
- Conditions
- Cardiotoxicity, Elderly, Cardiac Magnetic Resonance
- Trial name
- CARTIER (NCT03981588)
- Testing
- Imaging studies
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- AORTICA Group
Dementia, Cognitive Impairment
Physical Activity and Cerebral Metabolism in the Elderly: a Randomised Controlled Trial
Physical activity exerts a variety of long-term health benefits in older adults.This randomised controlled trial investigates the effect of a 12-week physical exercise program on the change in cerebral metabolism as assessed with…
- Trial name
- SMART (NCT02343029)
- Testing
- Individualised aerobic exercise training, Waiting Control
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Professor Johannes Pantel
Stroke, Intracranial Atherosclerosis
High-resolution Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaques in Ischemic Stroke
Intracranial atherosclerotic disease is the most common cause of ischemic stroke in Asia, also in China. Currently, despite vascular recanalization therapy, statins are one of the main drug choices for treating atherosclerotic…
- Conditions
- Stroke, Intracranial Atherosclerosis, High Resolution Magnetic Resonance Imaging
- Trial name
- NCT05897645
- Testing
- Registration
- Where
- China
- Volunteers
- 2,110 people
- Sponsor
- General Hospital of Shenyang Military Region
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