Clinical trials: Magnetic Resonance Imaging (MRI)
Healthy
Renal NCE-MRI in Healthy Volunteers
Non-contrast enhanced (NCE) structural MRI enables to investigate renal anatomy. Additional NCE-MR acquisition modalities (e.g. Diffusion Weighted Imaging (DWI), Blood Oxygenation Level Dependent (BOLD) MRI, Arterial Spin…
- Trial name
- NCT02618460
- Testing
- Non contrast-enhanced magnetic resonance imaging
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Intestinal Behcet Disease
Intestinal Ultrasound, Magnetic Resonance Enterography, and Conventional Assessment Tools Before and After Treatment of Intestinal Behcet's Disease
Background: The "treat-to-target" approach has recently been adopted in the treatment of inflammatory bowel disease (IBD). The basic premise is to define specific measurable targets and then adjust treatment until these targets…
- Trial name
- NCT06384391
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Yonsei University
Breast Cancer
Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
The goal of this clinical research study is to learn if magnetic resonance imaging (MRI) with magnetic resonance spectroscopy (MRS) can show the effects of pre-surgical chemotherapy in breast cancer patients who are eligible to…
- Trial name
- NCT00490503
- Testing
- Magnetic Resonance Imaging (MRI), Magnetic Resonance Spectroscopy (MRS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
To investigate multimodel MRI exploring the pathophysiology of multiple sclerosis and neuromyelitis optica spectrum disorders. The investigators use multimodel MRI to evaluate the extent of blood-brain barrier and white matter…
- Trial name
- NCT02836327
- Testing
- Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
MRI Imaging
Assessment of Investigational Magnetic Resonance Imaging and Post-Processing Procedures
The goals of this study are to (1) develop and optimize MRI acquisition and post-processing techniques and (2) to generate preliminary and comparative data on sequences for potential clinical trials.
- Trial name
- NCT03490656
- Testing
- MRI Scan - in addition to standard of care, MRI Scan - not in addition to standard of care
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Parkinson Disease
Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
- Trial name
- NCT06868160
- Testing
- Rehabilitation, tDCS, tsDCS (first cycle)
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Age-associated Memory Impairment
TMS for Investigating Memory Facilitation
The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals.
- Trial name
- NCT05462782
- Testing
- Transcranial Magnetic Stimulation (TMS) Cone Coil
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Pancreatic Cancer
Pre-Operative Staging of Pancreatic Cancer Using Superparamagnetic Iron Oxide Magnetic Resonance Imaging (SPIO MRI)
The purpose of this research study is to see if a specific kind of MRI, called Ultrasmall Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI), which uses an FDA-approved therapeutic agent(Feraheme) to see if it is…
- Trial name
- NCT00920023
- Testing
- Superparamagnetic Iron Oxide Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Prostate Cancer
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
Background: The ability to treat early prostate cancer is still limited. Thermal ablation methods are being tested for focal prostate cancer therapy. Researchers want to improve on these methods.
- Trial name
- NCT04808427
- Testing
- TULSA-PRO
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Pain
Personalized High-Definition tDCS Protocols for Chronic Pain Treatment
This study aims to examine the use of neurostimulation as a potential adjuvant treatment for chronic pain. Among neurostimulation techniques, transcranial direct current stimulation (tDCS) represents a promising, yet not fully…
- Trial name
- NCT07432841
- Testing
- Anodal High-Definition transcranial Direct Current Stimulation, Cathodal High-Definition transcranial Direct Current Stimulation
- Where
- 4 sites in Italy
- Volunteers
- 144 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Metastatic Prostate Cancer
PRAGMA (Prostate Radio Ablation Guided by Magnetic Resonance Imaging Acquisition) in Metastatic Prostate Cancer
Patients with metastatic prostate cancer can undergo MRI-guided prostate Stereotactic body radiation therapy (SBRT) without significant adverse events, similar to what has been reported for patients with localized prostate…
- Trial name
- PRAGMA (NCT04220983)
- Testing
- MR-Guided Prostate SBRT
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
Anorexia Nervosa
Functional Magnetic Resonance Imaging (fMRI) Imaging Study in Adolescents With Anorexia Nervosa
The purpose of this study is to use fMRI imaging technology to examine areas in the brain related to appetite, reward and cognition in adolescent women with eating disorders as compared to those who have never had an eating…
- Trial name
- ADOL_AN (NCT00978666)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Arterial Occlusive Diseases
Spectroscopy in Functional Assessment of Peripheral Artery Disease (spectroAMI)
To explore the reliability of P-31 MR spectroscopy mitochondrial function in patients with peripheral arterial occlusive disease.
- Trial name
- SPECTROAOMI (NCT03723473)
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Systolic Heart Failure, Dysynchrony
Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy
This randomized controlled trial will assess a cardiac MRI derived 4D digital cardiac model to optimized left and right ventricular lead delivery to improve response to cardiac resynchronization therapy.
- Conditions
- Systolic Heart Failure, Dysynchrony, Image Guidance, Digital Twins
- Trial name
- NCT01640769
- Testing
- 4D Model guided delivery of cardiac pacing leads, Standard CRT lead delivery
- Where
- 5 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Libin Cardiovascular Institute of Alberta
Heart Disease, Aging
Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.
Background: The prevalence of both senile cardiac amyloidosis (CA) and aortic stenosis (AS) markedly increases with age. Aortic stenosis increases left ventricular pressure overload.
- Conditions
- Heart Disease, Aging, Amyloidosis, Aortic Valve Stenosis
- Trial name
- AMYLOCARTESIAN (NCT02260466)
- Testing
- a basal LV septum biopsy
- Where
- 5 sites in France
- Volunteers
- 186 people
- Sponsor
- French Cardiology Society
Breast Neoplasm Female, Early Detection of Cancer
The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI
The purpose of this study is to test the impact of a multilevel decision support intervention on informed decisions about breast MRI among high-risk Black and Latina women.
- Conditions
- Breast Neoplasm Female, Early Detection of Cancer, Hereditary Breast and Ovarian Cancer Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT06892275
- Testing
- Enhanced Usual Care, Decision Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Georgetown University
Multiple Sclerosis
MR-Guided Focused Ultrasound (MRgFUS) for the Management of Tremor in Patients With Multiple Sclerosis
This study will be a single-centre, prospective, single-arm, open-label pilot trial assessing the feasibility and safety of unilateral MR-guided focused ultrasound (MRgFUS) thalamotomy for refractory hand tremor in up to 12…
- Trial name
- MSFUS001 (NCT04279912)
- Testing
- Focused Ultrasound (MRgFUS) for the Management of Tremor in Patients With Multiple Sclerosis
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Sunnybrook Health Sciences Centre
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Alcohol Use Disorder (AUD), Alcoholism
Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
This study looked at whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation treatment, could help adults with alcohol use disorder when added to their usual treatment.
- Trial name
- NCT07755046
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Ting-Gang Chang
Prostate Cancer
Clinical Value of FEC-PET Combined With Endorectal MRI for Pre-therapeutic Staging of Prostate Cancer
To investigate the sensitivity of the [18F]fluoroethylcholine (FEC) Positron-Emission-Tomography/ Magnetic Resonance Imaging (PET/MRI) method in tumour detection and location (side assignment, encapsulation, invasion of the…
- Trial name
- FEC-PET/MRI (NCT00520546)
- Testing
- 18F-Ethylcholine Positron Emission Tomography (FEC-PET), Endorectal Magnetic Resonance Imaging (1.5Tesla) (eMRI)
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Dr. Markus Hartenbach
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