Clinical trials: Magnetic Resonance Imaging Sequences
Healthy, Nervous System Disease
Functional and Metabolic Imaging Using Magnetic Resonance Imaging and Spectroscopy
Technical advances in magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have provided researchers with the opportunity to study changes of the central nervous system (CNS) and improve diagnosis and…
- Trial name
- NCT00001591
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Volunteers
Magnetic Resonance Imaging (MRI) Sequences Optimization in Healthy Subjects
Magnetic resonance imaging (MRI) is a noninvasive and non-ionizing (no use of X-rays) imaging modality. Today it is considered an anatomical and functional exploration reference technique.
- Trial name
- OSS-IRM (NCT02900339)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Liver Disease
T2 Weighted Imaging of the Liver With Fast Spin Echo MRI
The purpose of this study is to test two new MRI (magnetic resonance imaging) sequences to see how they compare to previously used imaging sequences as they may improve the quality of abdominal MRI.
- Trial name
- NCT02186054
- Testing
- MRI examinations
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Brain Tumor, Glioma
Metabolic Characterization of Space Occupying Lesions of the Brain
High field MR-technologies are expected to boost metabolic spectroscopic imaging (MRSI), but also CEST-MRI. This is due to the fact that increased SNR is available which can be used to increase the spatial resolution of all…
- Conditions
- Brain Tumor, Glioma, IDH Mutation
- Trial name
- FASTMRSI (NCT04233788)
- Testing
- MR-scans using a 3T Prisma and a 7T Terra scanner (Siemens, Erlangen Germany)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Subjects, Patient Performing an MRI Examination
Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam
The purpose of this study is to evaluate the optimization of MRI acquisition sequences.
- Trial name
- AIMANT (NCT04645628)
- Testing
- MRI examination
- Where
- France
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Uterine Cervical Neoplasms
MRI (Including Spectroscopy and Fat-Saturations and Diffusion-Weighted Imaging) in Cervical Cancer
To detect differences in MR spectroscopy, diffusion weighted MR, diffusion tensor imaging (DTI) or dynamic contrast enhancement (DCE) MR imaging between primary cervical tumors and normal cervical tissue.
- Trial name
- MRI (NCT01060033)
- Testing
- MR Spectroscopy, Fat-Saturation and Diffusion-Weighted Imaging, Dynamic Contrast Enhancement MRI (MR-DCE)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington University School of Medicine
Mild Cognitive Impairment, Alzheimer's Disease
Minocycline in Patients With Alzheimer's Disease
Cognitively normal individuals, patients with Mild Cognitive Impairment (MCI) or Alzheimer's Disease (AD) will undergo clinical screening, neuropsychological tests, blood and urine analyses, quantitative magnetic resonance…
- Trial name
- NCT01463384
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Huntington Medical Research Institutes
Degeneration of Spine and Osteoarticular
New MRI Sequences in Spine and Joint
Low back pain and osteoarticular degeneration or injury is the leading worldwide cause of years lost to disability, accounting for 17 % of all patients with disabilities and its burden is growing alongside the increasing and…
- Trial name
- NMSSJ (NCT04647279)
- Testing
- Dual-emission X-ray Absorptiometry
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Single-ventricle
Validation of Cardiac Magnetic Resonance Sequences in Patients With Single Ventricles
Single ventricle defects make up the severe end of the congenital heart disease spectrum. The Fontan operation leads to a complete redirection of systemic venous blood outside of the heart and directly into the lungs.
- Trial name
- NCT04017494
- Testing
- Cardiac Magnetic Resonance Imaging, Blood draw for hematocrit and heart failure biomarkers, Cardiopulmonary exercise test
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Barbara Burkhardt
Clinical Indication for a Head MRI
Magnetic Resonance Imaging Using Innovative Pulse Sequences
The purpose of the study is to collect in vivo human image data to demonstrate neurological magnetic resonance imaging (MRI) of subjects using short pulse sequences.
- Trial name
- NCT01724216
- Testing
- pulse sequences
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- GE Healthcare
Magnetic Resonance Imaging, Cardiac Magnetic Resonance Imaging
Evaluation of a Free-breathing Cardiac Cine-MRI Sequence With Image Reconstructions by Deep-Learning in Ischemic Heart Disease
Today, MRI is the gold standard for the precise assessment of left ventricular volume and function, but presents the drawback of having a long acquisition time and of generating motion artifacts, in particular respiratory…
- Conditions
- Magnetic Resonance Imaging, Cardiac Magnetic Resonance Imaging, Deep-Learning, Left Ventricular Ejection Fraction
- Trial name
- CINEDL (NCT05105984)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stroke, Acute, Angiography
Comparison Between TOF and SWAN Sequences in the Detection of Arterial Occlusion in Acute Ischemic Stroke Using MRI
Optimizing the MRI protocol in acute ischemic stroke remains a challenging issue. In this field, susceptibility-weighted sequences have proved their superiority over T2.
- Conditions
- Stroke, Acute, Angiography, Magnetic Resonance Imaging, Diagnosis
- Trial name
- TOF-SWAN (NCT03645902)
- Testing
- Magnetic resonance imaging
- Volunteers
- 34 people
- Sponsor
- Lille Catholic University
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Implementation of Work in Progress (WIP) Sequences in Magnetic Resonance Imaging (MRI)
Trial of new work in progress (WIP) sequences in MRI.
- Trial name
- NCT01019226
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Sheba Medical Center
Takotsubo Cardiomyopathy, Machine Learning
Prognotic Role of CMR in Takotsubo Syndrome
The primary objective of this observational registry is to develop a comprehensive clinical and imaging score (incorporating echocardiography and cardiac magnetic resonance data) that enhances risk stratification for patients…
- Conditions
- Takotsubo Cardiomyopathy, Machine Learning, Magnetic Resonance Imaging
- Trial name
- EVOLUTION (NCT06277297)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- University of Cagliari
Magnetic Resonance Imaging
Evaluation of 4D Magnetic Resonance Flow Sequence at Hepatic Level
The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency
- Trial name
- HEPAFLUX (NCT02821078)
- Testing
- 4D flow imaging sequence
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Myocardial Infarction
Comparative Evaluation of Various Combinable Magnetic Resonance (CMR) Pulse-sequences for Macrophage Imaging Using Ferucarbotran
The aim of this study is to: clarify whether macrophage imaging using ferucarbotran is able to delineate the region of myocardial infarction as accurate as gadolinium-based necrosis/fibrosis imaging; identify possible differences…
- Trial name
- NCT00886444
- Testing
- Ferucarbotran (Resovist)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Gastric Cancer
Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.
- Trial name
- NCT06735105
- Testing
- Scanning parameter
- Where
- China
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Yunnan Cancer Hospital
Fatigue, Stroke, Acute
Microstructure Imaging in Stroke Patients
The purpose of this study is to establish a methodological framework based on existing advanced neuroimaging technologies as a new clinical neuroimaging tool for assessment of possible affected brain connections in stroke and TIA…
- Conditions
- Fatigue, Stroke, Acute, Transient Ischemic Attack
- Trial name
- NCT04118790
- Testing
- Clinical Assessment, MRI scan
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Emphysema
Assessment of Emphysema Using 1.5T MRI With UTE Pulse Sequences
Emphysema is a major pathological feature of Chronic Obstructive Pulmonary Disease (COPD). Non-invasive assessment of emphysema is a crucial issue for the phenotype and follow-up of COPD patients.
- Trial name
- EMPHYREM (NCT02100800)
- Testing
- MR and CT measurements of emphysema quantification
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Bordeaux
Stroke, Ischemic
Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination.
Currently, standard brain MRI takes 20 to 25 minutes, but in the case of ischemic stroke, every minute counts to limit the extension of the necrotic core, with the possibility of recanalizing the occluded artery (intravenous…
- Trial name
- INDEX (NCT07199920)
- Testing
- Achieva 3.0T dStream Philips
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble