Clinical trials: Magnetism
Breast Cancer
Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)
The purpose of this study is to look at the efficacy (how does it work) and safety of gadobutrol when used for obtaining MR images of both breasts.Women with a recent diagnosis of breast cancer by mammogram (X-ray examination of…
- Trial name
- GEMMA 2 (NCT01104584)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 48 sites in United States, Argentina and 7 more
- Volunteers
- 460 people
- Sponsor
- Bayer
Concussion, Mild, Post-Concussion Symptoms
Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) or "concussions" are an increasingly prevalent injury in our society. Patients with post-concussion syndrome have been shown to have deficits on tests of short term memory, divided attention…
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT01747811
- Testing
- wavelength-1 bright light, wavelength-2 bright light
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Lower Back Pain
Treatment of Back Pain Using Transcutaneous Magnetic Stimulation (TCMS)
This is a single-site, randomized, Single-blinded, placebo-controlled, trial of Transcutaneous Magnetic Stimulation (TCMS) for the treatment of lower back pain.
- Trial name
- NCT02421757
- Testing
- Fischell Transcutaneous Magnetic Stimulation Pain Treatment Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Cocaine Use Disorder, Methamphetamine Abuse
rTMS for Stimulant Use Disorders
The purpose of the study is to determine feasibility of repetitive transcranial magnetic stimulation (rTMS) for individuals with moderate to severe cocaine or methamphetamine use disorder (CUD/MUD).
- Conditions
- Cocaine Use Disorder, Methamphetamine Abuse, Cocaine Dependence, Methamphetamine Dependence
- Trial name
- CTN-0108 (NCT04907357)
- Testing
- rTMS
- Where
- 4 sites in United States
- Volunteers
- 129 people
- Sponsor
- Medical University of South Carolina
The Focus of the Study is to Reduce the Risk of Stroke and Life-threatening Bleeding Events in Patients With Non-valvular Atrial Fibrillation
WATCHMAN FLX™ CT Study
WATCHMAN FLX™ CT is a prospective, single-arm, single-center, post-market investigation to assess device tissue coverage in subjects with non-valvular atrial fibrillation (AF) who receive the WATCHMAN FLX device to reduce the…
- Trial name
- NCT05324371
- Testing
- Watchman FLX Device
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease
Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Subjects being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 2 (NCT01890434)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 24 sites in United States, Australia and 2 more
- Volunteers
- 478 people
- Sponsor
- Bayer
Schizophrenia, Negative Type; Schizophrenic
Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia
The main purpose of this study is to learn how transcranial magnetic stimulation (TMS) helps improve negative symptoms of schizophrenia.
- Conditions
- Schizophrenia, Negative Type; Schizophrenic, Schizo Affective Disorder
- Trial name
- NCT03648268
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hemiparesis, Stroke
A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training
The purpose of this study is to determine whether the combination of low frequency repetitive transcranial magnetic stimulation (rTMS) and motor-imagery-based brain computer interface (BCI) training is effective for enhancing…
- Trial name
- NCT02132520
- Testing
- rTMS, BCI Training
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Minnesota
Autism Spectrum Disorder, Depression
TMS for Adults With Autism and Depression
The goal of this proposal is to investigate whether a standard rTMS protocol for depression, including multiple sessions applied to left dorsolateral prefrontal cortex (DLPFC) results in reduction of depressive symptoms for adult…
- Conditions
- Autism Spectrum Disorder, Depression, Depressive Disorder, Major Depressive Disorder
- Trial name
- TAD (NCT02939560)
- Testing
- NeuroStar® TMS device (Neuronetics, Atlanta, GA)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Beta Rhythm, Tactile Perception
Beta Events and Sensory Perception
Low-frequency brain rhythms in the alpha (8-14Hz) and beta (15-29Hz) bands are strong predictors of perception and functional performance in a range of tasks, and are disrupted in several disease states.
- Trial name
- NCT04062318
- Testing
- Online Active SI-Hand TMS, Online Active Control TMS
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Brown University
Traumatic Brain Injury
rTMS to Improve Cognitive Function in TBI
This project will study 40 Veterans identified with symptoms understood to characterize mild to moderate Traumatic Brain Injury (TBI) including Post Traumatic Stress Disorder (PTSD).
- Trial name
- rTMSTBI (NCT02152540)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication.
- Trial name
- DoDNAC (NCT04481048)
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Clinical Indication for a Head MRI
Magnetic Resonance Imaging Using Innovative Pulse Sequences
The purpose of the study is to collect in vivo human image data to demonstrate neurological magnetic resonance imaging (MRI) of subjects using short pulse sequences.
- Trial name
- NCT01724216
- Testing
- pulse sequences
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- GE Healthcare
Cancer of Lymph Node
Clinical and Technical Feasibility of a Ultrasuperparamagnetic Nanoparticle Iron Oxide (USPIO)-Enhanced Magnetic Resonance Lymph Node Imaging
The goal of this clinical research study is to learn if the drug Feraheme ® (ferumoxytole) helps researchers most clearly to "see" cancerous lymph nodes on an MRI scan.
- Trial name
- NCT01815333
- Testing
- Feraheme, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nicotine Dependence
TMS-fMRI for Neural Pathway in Smokers
Cigarette smoking causes significant morbidity and mortality in the United States. Smoking cessation is difficult, with the average smoker attempting to quit five times before permanent success.
- Trial name
- NCT02665338
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xingbao Li
Bipolar Disorder
Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder
Bipolar Disorder (BD) is a common and highly debilitating psychiatric disorder, however, the predisposing brain mechanisms are poorly understood.
- Trial name
- NCT05179785
- Testing
- Continuous Theta Burst Stimulation (cTBS), Intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mary Phillips, MD MD (Cantab)
Brain Tumor
Multihance at 3 Tesla (3T) in Brain Tumors
Compare the efficacy of MultiHance and Magnevist
- Trial name
- NCT00395863
- Testing
- Multihance, Arm 2 - Magnevist
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Bracco Diagnostics, Inc
Diabetes Mellitus
A Study Comparing the Effect of Albiglutide With Exenatide on Regional Brain Activity Related to Nausea in Healthy Subjects
The drug effects will be studied after a single dose of 50 milligram (mg) albiglutide and a single dose of 10 microgram exenatide, to gain insight into the central mechanisms of nausea associated with Glucagon-like peptide-1…
- Trial name
- NCT02802514
- Testing
- Albiglutide 50mg, Exenatide 10microgram
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Anxiety Disorders
PharmacofMRI (Functional Magnetic Resonance Imaging) of Anxiolytic Medications (Alprazolam)
The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy controls to examine the acute effects of certain anxiolytic medications on brain function.
- Trial name
- NCT00703885
- Testing
- 0.25 mg alprazolam, 1.0 mg alprazolam
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
ADHD
Proton Magnetic Spectroscopy in Children and Adolescents With ADHD Before and After Treatment With OROS Methylphenidate
This will be an open label study using daily does of up to 126mg/day of Concerta in the treatment of children and adolescents, ages 12-17, who meet DSM-IV criteria for ADHD.
- Trial name
- NCT00593112
- Testing
- OROS methylphenidate, No intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital