Clinical trials: Magnetism
Focal Epilepsy, Transcranial Magnetis Stimulation
Transcranial Magnetic Stimulation (rTMS) for Refractory Focal Epilepsy
Epilepsy as a brain disease is characterised by enhanced brain excitability. Low frequency repetitive transcranial magnetic stimulation (rTMS) can be an effective treatment for refractory focal epilepsy.
- Trial name
- NCT06681480
- Testing
- figure-of-eight active rTMS coil device
- Where
- Slovakia
- Volunteers
- 20 people
- Sponsor
- Comenius University
Bariatric Surgery Candidate, Hiatal Hernia
Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device
The purpose of this study is to evaluate the safety and effectiveness of the Extended Magnetic Grasper Device in patients undergoing bariatric and/or hiatal hernia procedures, as a liver retractor grasping the liver and/or the…
- Trial name
- NCT06432088
- Testing
- Extended Magnetic Grasper Device
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Levita Magnetics
Tinnitus
Individualized Treatment of Patients With Chronic Tinnitus With Repetitive Transcranial Magnetic Stimulation
In the first visit a magnetic resonance imaging measurement will be done for the use of a neuronavigation System with the aim to control for stable coil position over the course of the trial.
- Trial name
- indiTMS (NCT03957122)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- University of Regensburg
Traumatic Brain Injury
Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury
Background: Traumatic brain injury may have a range of effects, from severe and permanent disability to more subtle functional and cognitive deficits that often go undetected during initial treatment.
- Trial name
- NCT01132937
- Where
- United States
- Volunteers
- 886 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injury, Hyperalgesia, Secondary
MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI
The goal of this study is to compare the changes that occur in sensation and chemical properties of the brain following SCI between individuals that experience chronic pain and those that do not, and between those with SCI and…
- Conditions
- Spinal Cord Injury, Hyperalgesia, Secondary, Hyperalgesic Sensations
- Trial name
- MRS (NCT00561782)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Depressive Disorder, Major
Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder?
Repeated Transcranial Magnetic Stimulation - R.TMS - is currently part of the treatment for depressive illness. This non-invasive technique is designed to stimulate certain areas of the cerebral cortex involved in this pathology.
- Trial name
- DESTIMCARE (NCT03436823)
- Testing
- nurse semi-structured interview, Music & Relaxation with eyes closed
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Osteoarthritis, Knee, Perfusion
Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis
Patients with osteoarthritis of the knee undergo visible joint changes in radiology and Magnetic resonance imaging (MRI) tests, but also clinically and histologically.
- Conditions
- Osteoarthritis, Knee, Perfusion, Bone Marrow, Magnetic Resonance Imaging
- Trial name
- Chondrolike (NCT03644420)
- Testing
- Clinical evaluation, Radiology, Dynamic contrast-enhanced magnetic resonance imaging
- Volunteers
- 22 people
- Sponsor
- Lille Catholic University
Episodic Memory Retrieval
rTMS Brain Stimulation and Cognition
This study will use repetitive transcranial magnetic stimulation (rTMS) (a way to use a powerful magnet to cause temporary impairment to the function of a brain region) to test whether certain parts of the brain are necessary to…
- Trial name
- NCT04244682
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stephan Hamann
Stroke, Ischemic
The Efficacy of Citalopram Treatment in Acute Stroke
We wish to conduct a prospective, randomized, double blind, placebo controlled multi center study of the combined neuroprotective and antithrombotic effects of SSRI treatment after stroke.
- Trial name
- TALOS (NCT01937182)
- Testing
- Citalopram
- Where
- 3 sites in Denmark
- Volunteers
- 642 people
- Sponsor
- University of Aarhus
Transcranial Magnetic Stimulation, Freezing of Gait
Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Freezing of Gait
To investigate the treatment effect of Theta-burst Transcranial Magnetic Stimulation (TBS) on patients with freezing of gait (FOG) and the underlying neural mechanism.
- Trial name
- NCT05192759
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Myocarditis, Takotsubo Cardiomyopathy
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)
Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues.
- Conditions
- Myocarditis, Takotsubo Cardiomyopathy, Reversible Coronary Ischaemia
- Trial name
- MEMORY (NCT04623788)
- Testing
- Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Dysphagia After Stroke, Cortical Swallowing Network
To Explore the Functional Connectivity Pattern of Cortical Swallowing Network in the Oral Phase of Post-stroke Dysphagia Based on Dynamic Causal Modelling
Swallowing activity in the oral phase is regulated by the cortical swallowing network, and the functional connectivity pattern of the cortical swallowing network is related to swallowing activity.
- Conditions
- Dysphagia After Stroke, Cortical Swallowing Network, Functional Magnetic Resonance Imaging, Oral Phase
- Trial name
- NCT06564688
- Testing
- Swallowing function test
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Sudden Cardiac Death
Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardioverter-Defibrillators (DUTCH-ICD)
Research questions: The value of primary prevention implantable cardioverter-defibrillator implantation (ICD) therapy in patients with non-ischemic cardiomyopathy (NICM) is under debate.
- Trial name
- DUTCH-ICD (NCT07415642)
- Testing
- ICD implantation
- Where
- 2 sites in Netherlands
- Volunteers
- 720 people
- Sponsor
- University Medical Center Groningen
Healthy Volunteers
Healthy Lung Study- Development of 3T MRI Hardware and Software for 3He Gas Imaging of the Lung: Healthy Volunteer Development Study
Healthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
- Trial name
- NCT03169673
- Testing
- Hyperpolarized Helium 3 Magnetic Resonance Imaging
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Rheumatoid Arthritis
A Study of Efficacy of Rituximab [Mabthera/Rituxan] in Patients With Rheumatoid Arthritis Using Magnetic Resonance Imaging of the Hand (RESONAR)
This randomized, double-blind, placebo controlled, parallel group study will assess the efficacy and safety of rituximab [MabThera/Rituxan] in patients with severe active rheumatoid arthritis refractory to at least one anti-TNF…
- Trial name
- NCT01117129
- Testing
- rituximab [MabThera/Rituxan], methotrexate
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Hoffmann-La Roche
Stroke
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to improve learning of movement skills and the adaptation processes in patients after stroke.
- Trial name
- NCT00715520
- Testing
- Transcranial Magnetic Stimulation (TMS), Carbidopa-Levodopa, Methylphenidate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Cortical Pharyngeal Area: Excitability, Facilitation and Plasticity in Healthy Subjects
The aims of this study are in four experimental sessions. The aims are: to characterize the excitability of the cortical pharyngeal area with pharyngeal pressure and electromyograms (EMGs), at rest, in awake healthy subjects; to…
- Trial name
- NCT00213382
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Prebiotics, Anxiety
Gut-brain Axis, Brain Function, and Behaviour.
The aim is to test if dietary supplementation with prebiotics reduces measures of anxiety in healthy human participants with high self-reported levels of anxiety.
- Conditions
- Prebiotics, Anxiety, Humans, Magnetic Resonance Imaging
- Trial name
- NCT03554694
- Testing
- Prebiotics
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes, Endothelial Dysfunction
Magnetic Resonance Imaging of Vascular Function
A major function of blood vessels is to control blood flow by dilating or constricting depending on the demand. Vascular dysfunction is a state in which blood vessels fail to carry out its normal roles such as regulating blood…
- Trial name
- NCT02206919
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Heart Failure and Reduced Ejection Fraction, Heart Failure
PRIMA-HF: Predicting Myocardial Recovery in Heart Failure Using Cardiac Imaging HAI-HF: High Dosing vs. Standard Dosing Adenosine During Myocardial Perfusion in Heart Failure
Background: Heart failure with reduced ejection fraction (HFrEF) is a heterogeneous condition with variable potential for left ventricular ejection fraction (LVEF) recovery.
- Trial name
- PRIMA-HF (NCT07243119)
- Testing
- HAI-HF: Adenosine Stress [¹⁵O]H₂O PET Imaging, Two different doses of adenosine
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Gødstrup Hospital
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