Clinical trials: Magnetism
Speech
Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS)
The purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to…
- Trial name
- NCT05723575
- Testing
- TMS, somatosensory acuity measurement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Muscle Weakness
Magnetic Muscle Stimulation of Abdominal Muscle
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- MMS (NCT04199312)
- Testing
- Magnetic Muscle Stimulation (MMS) device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Tourette Syndrome
Response Inhibition in Tourette Syndrome
Tics are the hallmark symptoms in Tourette Syndrome. Patients with Tourette Syndrome have difficulties controlling unwanted movements.
- Trial name
- NCT03628703
- Testing
- Repetitive TMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804296
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Paul E. Croarkin
Stroke, Hemiparesis
Perinatal Stroke: Understanding Brain Reorganization
The incidence of perinatal stroke is relatively common, as high as 1 in 2,300 births, but little is known about the resulting changes in the brain that eventually manifest as cerebral palsy (CP).
- Trial name
- NCT02743728
- Testing
- Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, General Movement Assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Coronary Artery Disease, CAD
Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies
This is a pilot study in a patient population with suspected coronary artery disease (CAD) as defined by the presence of a prior abnormal nuclear (PET/SPECT) myocardial perfusion scan.
- Trial name
- NCT01949844
- Testing
- regadenoson, Optimark®, Myocardial perfusion MRI
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Daniel S. Berman
Obsessive-Compulsive Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) for Obsessive-Compulsive Disorder (OCD)
The study aims to assess the impact of repetitive transcranial magnetic stimulation (rTMS) on brain imaging and neurophysiological measures of cognitive control in patients with Obsessive-Compulsive Disorder (OCD).
- Trial name
- NCT02904356
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Ventricular Tachycardia
Magnetic Stimulation to Treat VT Storm
Ventricular Tachycardia storm is a medical emergency characterized by three or more episodes of ventricular arrhythmia within 24 hours and associated with a significantly increased mortality and massive health resource…
- Trial name
- STAR-VT (NCT04043312)
- Testing
- Magstim SuperRapid
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Breast Cancer, Invasive Ductal
Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer
The purpose of the study is to evaluate the efficacy of a dedicated Magnetic Resonance guided High Intensity Focused Ultrasound (MR-HIFU) unit in ablating breast cancer by comparing MR imaging and pathologic specimen after…
- Trial name
- NCT03560102
- Testing
- Philips Sonalleve® MR-HIFU Breast Therapy System
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Kantonsspital Winterthur KSW
Acute Stress Reaction
Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands
The purpose of this study is to explore the effect of Neurexan® on the brain response when participants undergo an emotional stressful condition in verum compared to placebo.
- Trial name
- NEURIM (NCT02602275)
- Testing
- Neurexan
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Biologische Heilmittel Heel GmbH
Healthy Volunteer
Repetitive Transcranial Magnetic Stimulation Equipment Testing and Pilot Study
Background: Brain stimulation called repetitive transcranial magnetic stimulation (rTMS) may help people quit drugs. Researchers want to study how it works in healthy people first.
- Trial name
- NCT02231892
- Testing
- TMS
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Magnetic Resonance Imaging
Comparison of Gadovist 75% Standard Dose to Dotarem at Full Standard Dose
The study was conducted to gain knowledge about a new dose of a diagnostic drug that is used for contrast-enhanced Magnetic Resonance Imaging (MRI) of the human central nervous system (CNS).
- Trial name
- LEADER 75 (NCT03602339)
- Testing
- Gadoterate (Dotarem/Clariscan), Gadobutrol (Gadavist/Gadovist, BAY86-4875)
- Where
- 20 sites in United States, France and 5 more
- Volunteers
- 157 people
- Sponsor
- Bayer
Schizophrenia, Schizoaffective Disorder
Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation
The purpose of this study is to determine whether repetitive transcranial magnetic stimulation (rTMS) is effective in remediating cognitive deficits while also improving functionality in Veterans with schizophrenia.
- Trial name
- NCT03037983
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Hiv, Tobacco Smoking
Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation.
- Trial name
- NCT05295953
- Testing
- TBS
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Gopalkumar Rakesh
Rheumatoid Arthritis
Randomised Double-Blind, Placebo-Controlled, Parallel Group Study in Patients With Active Rheumatoid Arthritis:Magnetic Resonance Imaging Sub-Study
This is a sub-study of the OSKIRA-4 study, (D4300C0004, NCT01264770) to explore alternative and more sensitive modalities for measuring the beneficial effects of syk inhibition with fostamatinib in patients with active RA.
- Trial name
- OSKIRA 4 SS (NCT02092961)
- Testing
- Fostamatinib, Adalimumab
- Where
- 21 sites in United States, Bulgaria and 9 more
- Volunteers
- 198 people
- Sponsor
- AstraZeneca
Alzheimer's Disease
Neural Correlates In Mild Alzheimer's Disease
The objective of this study was to identify neural correlates of cognitive improvement after 3 months of donepezil hydrochloride treatment using either or both of two functional magnetic resonance imaging (fMRI) measures - the…
- Trial name
- NCT00477659
- Testing
- Donepezil hydrochloride
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eisai Inc.
Schizophrenia, Hallucinations
Transcranial Magnetic Stimulation for "Voices"
This study will determine the efficacy of MRI-guided transcranial magnetic stimulation (TMS)in reducing "voices" and other symptoms experienced by people with schizophrenia and schizoaffective disorder.
- Trial name
- NCT00308997
- Testing
- 1-hertz Repetitive Transcranial Magnetic Stimulation, Active 1-Hertz Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Yale University
Fibromyalgia
Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia
The purpose of this study is to evaluate the effect of milnacipran on how the brain processes pain in patients with fibromyalgia and to assess the relationship between this effect and brain activation patterns during functional…
- Trial name
- NCT00793520
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Forest Laboratories
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training
This study seeks to understand emotion regulation in those with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06132659
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Michigan
Parkinson Disease
Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers
The purpose of this study is to find out whether ubiquinol is well tolerated, can affect the symptoms of Parkinson's Disease and change the energy levels in the brain.
- Trial name
- NCT03061513
- Testing
- Ubiquinol
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University