Clinical trials: Magnetism
Rheumatoid Arthritis
Examination of the Effectiveness of Diffusion Weighted Magnetic Resonance Imaging for Identifying Poor Prognosis in Patients With Rheumatoid Arthritis
Diffusion Weighted Imaging (DWI) MRI will assist in differentiating poor prognosis bone oedema more effectively than traditional T2 weighted MRI in patients with early Rheumatoid Arthritis (RA).
- Trial name
- NCT01482507
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Optimus Clinical Research
Cystic Fibrosis
Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation
Cystic Fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The encoded protein, CFTR, is an epithelial chloride ion channel responsible for aiding in the regulation of salt…
- Trial name
- NCT01161537
- Testing
- VX-770
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Chronic Kidney Diseases
Eye-Brain-Kidney in CKD
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD).
- Trial name
- NCT07358572
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Friendship Hospital
Alzheimer Disease
HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease
This study involves imaging participants' brains using MRI. The goal is to develop a high-resolution, high-sensitivity imaging tool, hyperpolarized xenon functional brain magnetic resonance imaging, which can provide more…
- Trial name
- NCT02638519
- Testing
- Traditional Proton fMRI, Hyperpolarized Xenon-129 fMRI, Hyperpolarized Xenon-129
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Thunder Bay Regional Health Research Institute
Neuropathic Pain, Orofacial Pain
Bilateral TMS vs. Unilateral TMS
Rationale: In 2016, Henssen et al. discuss that orofacial pain may be conducted in a bilateral fashion, inducing activation of both thalami [1].
- Conditions
- Neuropathic Pain, Orofacial Pain, Trigeminal Neuropathy
- Trial name
- biTMSvsuniTMS (NCT03710967)
- Testing
- Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Radboud University Medical Center
Mild Cognitive Impairment
iTBS rTMS in Mild Cognitive Impairment
The purposes of this research are to test whether it is feasible to administer a treatment protocol called intermittent theta burst stimulation (iTBS) repetitive transcranial magnetic stimulation (rTMS) in adults with mild…
- Trial name
- NCT05327257
- Testing
- iTBS rTMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maria I. Lapid, M.D.
Pleasure
RS-fMRI to Nutrient Shakes
Resting state functional magnetic resonance imaging (rsfMRl) of the brain is used to measure pleasantness after consumption of four different milkshakes with added sugars or sweeteners.
- Trial name
- NCT02745730
- Testing
- Glucose, Fructose, Sucralose
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Tissue Adhesions
Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions
Official title: Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI) detecting intra-abdominal adhesions Background: Adhesions are a frequent problem in abdominal surgery.
- Trial name
- NCT00882167
- Testing
- CineMRI
- Where
- 5 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Osteoporosis
Effect of Magnetic Therapy and Moderate Aerobic Exercise on Post Thyroidectomy Osteoporosis
Objectives; This study was conducted to investigate the effect of pulsed magnetic therapy and aerobic exercise on post thyroidectomy osteoporosis.
- Trial name
- NCT04488328
- Testing
- patients received the routine medical treatment in addition to pulsed magnetic therapy and moderate-intensity aerobic exercise for 12 weeks
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Stroke, Stroke, Cardiovascular
EMG Control Assistance Virtual Reality Interface Coupled With Cerebellar-iTBS for Arm Recovery After Stroke (ERICA)
The investigators hypothesize that a myoelectric (EMG) controlled virtual reality (VR) interface allows for effective upper limb motor recovery of stroke patients.
- Trial name
- ERICA (NCT06911671)
- Testing
- Virtual Reality Interface + Cerebellar iTBS (c-iTBS), Physical Therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Glioblastoma
Combined Approach to Resection of Glioblastoma (GBM) by 5-Aminolevulinic Acid (5-ALA) and Intraoperative Magnetic Resonance Imaging (MRI)
In the treatment of glioblastoma (GBM) neurosurgical resection of the tumor is usually considered a a first step of effective therapy.
- Trial name
- NCT01208909
- Testing
- diagnostic 5-ALA and MRI for tumor resection
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Neonatal Hyperbilirubinemia
MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates
The aim of the research was to define the role of MRS and ABR as early predictors of bilirubin-induced neurologic dysfunction (BIND) in full-term neonates who required intervention (phototherapy or exchange transfusion).
- Trial name
- NCT06018012
- Testing
- MRS and ABR
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tanta University
MRI Sedation, Pediatric Sedation
Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
The most common imaging procedure requiring sedation/anesthesia for the pediatric population is magnetic resonance imaging (MRI). However, the optimal anesthetic/sedation plan has not been determined for these procedures.
- Conditions
- MRI Sedation, Pediatric Sedation, Propofol Dosage, Emergence Delirium, Anesthesia
- Trial name
- NCT07369128
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg, Propofol (IV) 2-4 mg/kg, Dexmedetomidine (IV) 1 mcg/kg
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Boston Children's Hospital
Pulmonary Embolism
Pulmonary Rehabilitation to Improve Physical Capacity After Pulmonary Embolism
This project aims to evaluate a rehabilitation program as treatment and uncover potential pathophysiological mechanisms of a newly identified chronic condition named "Post Pulmonary Embolism Syndrome" (PPS).
- Trial name
- NCT03405480
- Testing
- Rehabilitation
- Where
- Norway
- Volunteers
- 209 people
- Sponsor
- Ostfold Hospital Trust
Substance Use, Healthy
Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model
This study seeks to understand individual differences in personality, brain function, and behavior. Study hypothesis: A stronger sign-tracking bias will be associated with a bottom-up processing style characterized by less…
- Trial name
- SIGN (NCT07094061)
- Testing
- fMRI, Questionnaires and surveys, Behavioral tasks and eye tracking
- Where
- 2 sites in United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postpoliomyelitis
Brain Physiology in Polio Survivors
OBJECTIVE: Many persons who survive poliomyelitis develop pain, weakness, and fatigue many decades later. It is not known why some persons develop this syndrome and others do not.
- Trial name
- NCT00080600
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Heart Failure
Brain Volume and Cardiac Function in Heart Failure
Patients with heart failure (HF) exhibit greater structural brain alterations and higher dementia risks than the general population.
- Trial name
- NCT06623344
- Testing
- Magnetic Resonance Imaging with or without Contrast
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
Stroke
Repetitive Transcranial Magnetic Stimulation in Spatial Attention After Stroke
Randomized Controlled Trial (RCT) aiming at assessing the efficacy of a novel rehabilitation protocol, based on repetitive transcranial magnetic stimulation (r- TMS) in combination with a conventional cognitive treatment (CCT).
- Trial name
- r-TMS (NCT04080999)
- Testing
- r-TMS
- Where
- 2 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Azienda Usl di Bologna
Stroke, Swallowing Disorders
Comparison of NMES, tDCS, and TMS Treatments in Post-Stroke Dysphagia
This randomized, single-blind, controlled clinical trial aims to compare the effectiveness of neuromuscular electrical stimulation (NMES) administered alone or in combination with transcranial direct current stimulation (tDCS) or…
- Conditions
- Stroke, Swallowing Disorders, Dysphagia
- Trial name
- NCT07793799
- Testing
- Neuromuscular Electrical Stimulation, Active Transcranial Direct Current Stimulation, Active Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Ulcerative Colitis, Irritable Bowel Syndrome
Cerebral Resonance Magnetic Imaging During Rectal Distention
Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown.
- Trial name
- NCT00213330
- Testing
- rectal distension
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
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