Clinical trials: Magnetism
Breast Cancer
Is Lipid Mapping an Effective Early Detection Tool for Breast Cancer in High-risk Populations?
This study aims to investigate if lipid composition mapping using magnetic resonance imaging could improve early and accurate cancer detection in genetic mutation carriers at high risk of breast cancer.
- Trial name
- NCT03949946
- Testing
- Magnetic resonance imaging (MRI)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Aberdeen
Sleep Deprivation, Hippocampal Atrophy
Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume
Sleep is a physiological state that is essential for human performance, including academic, occupational, interpersonal, and psychological aspects.
- Conditions
- Sleep Deprivation, Hippocampal Atrophy, Cortical Irregularity
- Trial name
- NCT06260280
- Testing
- Cerebral Nuclear Magnetic Resonance
- Where
- Mexico
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Prostate Cancer
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis
The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low.
- Trial name
- multiIMPROD2 (NCT04287088)
- Testing
- A shared decision making
- Where
- 4 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Cardiovascular Diseases
Inter-field Strength Agreement of CMR Derived Strain
Magnetic Resonance Imaging (MRI) scanners create a strong magnetic field around the body to produce a detailed picture of parts of the body. This can provide a lot of useful information about how the heart looks and works.
- Trial name
- NCT04475627
- Testing
- Cardiovascular Magnetic Resonance (CMR) imaging at 1.5T, Cardiovascular Magnetic Resonance (CMR) imaging at 3T
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Major Depression, Fibromyalgia
A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia
In this pilot study, the PI proposes to include 20 African American participants with Fibromyalgia to explore the effect of r TMS on pain and depressive symptoms.
- Trial name
- TMS (NCT00523302)
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Major Depression
Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101
In this pilot study, investigators aim to combine D-cycloserine, lurasidone, and single-day repeated intermittent Theta Burst Stimulation (iTBS) to preliminarily assess clinical improvement in an open-label cohort and monitor for…
- Trial name
- SPARC-LI (NCT07785102)
- Testing
- TMS, NRX-101
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mclean Hospital
Headache, Migraine
The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography
To examine the ability of MRA to measure the effect of GTN on the intra-cranial vascular response during the GTN-induced headache in healthy volunteers.
- Conditions
- Headache, Migraine, MR-Angiography, Healthy Volunteers
- Trial name
- NCT00256802
- Testing
- MR-angiography, GTN
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Left Ventricular Hypertrophy, Hypertension
Response of the Myocardium to Hypertrophic Conditions in the Adult Population
Hypertension and aortic stenosis are the two leading conditions that cause thickening of the heart muscles (left ventricular hypertrophy). Left ventricular hypertrophy is initially adaptive to maintain optimal heart function.
- Conditions
- Left Ventricular Hypertrophy, Hypertension, Myocardial Fibrosis
- Trial name
- NCT02670031
- Testing
- Cardiovascular Magnetic Resonance, Echocardiogram, Electrocardiogram
- Where
- Singapore
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Hyperlipidemia
Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS
To determine safety and effectiveness of low-dose therapeutic AEGR-733 +/- atorvastatin, ezetimibe or fenofibrate (compared to placebo) on liver fat accumulation measured by Magnetic Resonance Spectroscopy
- Trial name
- NCT00559962
- Testing
- AEGR-733, AEGR-733 and atorvastatin, AEGR-733 and fenofibrate
- Where
- 15 sites in United States
- Volunteers
- 260 people
- Sponsor
- Aegerion Pharmaceuticals, Inc.
Congenital Heart Disease, Mother Child Interaction
Creative Music Therapy in Newborns With Congenital Heart Disease
In the context of a clinical trial, the investigators will evaluate if parent-infant interaction can be improved by a family integrated, individualised, interactive resource- and needs-oriented music therapy approach in the dyads…
- Trial name
- BOND (NCT05702203)
- Testing
- Creative Music Therapy
- Where
- Switzerland
- Volunteers
- 164 people
- Sponsor
- University Children's Hospital, Zurich
Magnetic Resonance Imaging
Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle
This is a contrast-enhanced magnetic resonance imaging (MRI) study conducted on a single-administration of polyglucose superparamagnetic iron oxide injection.
- Trial name
- NCT06010537
- Testing
- polysaccharide superparamagnetic iron oxide injection
- Where
- China
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Chronic Migraine
Double-blind Randomized Clinical Trial of Transcranial Magnetic Stimulation in Chronic Migraine
The purpose of this study is to determine whether active repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex is safe and effective for preventive treatment of chronic migraine, compared to…
- Trial name
- TMS-CHROMIG (NCT01496950)
- Testing
- 10Hz active rTMS
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Hospital Israelita Albert Einstein
Acute Kidney Injury
MRI Changes of Acute Kidney Injury in COVID-19
This is a prospective observational cohort study that will aim to recruit 60 participants who have had COVID-19, were admitted to hospital, required intensive care, and/or developed AKI during their hospital stay.
- Trial name
- MRI-AIDED (NCT04594291)
- Testing
- MRI scans
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Pain
Efficacy of rTMS (Repetitive Transcranial Magnetic Stimulation) on Patients With Somatoform Pain Disorder
Chronic somatoform pain is common in psychiatric patients. Chronic somatoform pain causes significant distress and disrupts social functioning. Moreover, chronic somatoform pain often does not sufficiently respond to medication.
- Trial name
- NCT00726791
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Samsung Medical Center
Paroxysmal Atrial Fibrillation
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).
- Trial name
- EXCLAMATORY (NCT06212791)
- Testing
- Self- Report Evaluation-Duke Activity Status Index, Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire, Cardiopulmonary exercise test (CPET)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Virginia Commonwealth University
Interhemispheric Inhibition
Interaction of Right and Left Brain Hemispheres in Learning Precision Hand Movements
This study will examine how the two sides of the brain interact when learning precision hand movements. Both sides of the brain are active when a person performs an accurate hand movement.
- Trial name
- NCT00295568
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pain Management, Capsaicin-Induced Pain
TaVNS for Capsaicin-Induced Pain
Effective pain management remains a major clinical challenge. Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising, non-invasive neuromodulation technique due to its safety, ease of administration…
- Conditions
- Pain Management, Capsaicin-Induced Pain, Transcranial Magnetic Stimulation Repetitive, Electroencephalography
- Trial name
- NCT07719868
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Depression / Major Depressive Disorder
Longitudinal Effects of Brain Stimulation on Decision-Making and Reward Learning
This study investigates the longitudinal effects of brain stimulation treatments on decision-making and reward learning. Here, daily assessments of reinforcement learning behavior are used in patients with depression who receive…
- Trial name
- NCT07823218
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Bonn
Diabetes Mellitus, Type II
Detection of Diffuse Scar in Patients With Diabetes
People with diabetes are at an increased risk of heart attacks and heart failure, and it is important to be able to treat people with diabetes who are at risk for heart disease to prevent these outcomes.
- Trial name
- NCT01794091
- Testing
- Eplerenone
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Prostate Cancer
Magnetic Resonance Imaging in Detecting Cancer Progression in Patients With Early Stage Prostate Cancer Undergoing Active Surveillance
RATIONALE: Sometimes prostate cancer may not need treatment until it progresses. In this case, active surveillance may be sufficient.
- Trial name
- NCT00796874
- Testing
- active surveillance, imaging biomarker analysis, biopsy
- Sponsor
- Roswell Park Cancer Institute
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