Clinical trials: Magnetism
Paralytic Lagophthalmos, Corneal Exposure
Self-Adhering Magnetic Device to Treat Corneal Exposure
Paralytic lagophthalmos can be difficult to treat and manage. It has a host of causes and effects, one of which (for the latter) is exposure keratopathy.
- Trial name
- NCT06291818
- Testing
- temporary magnetic system for tarsorrhaphy (MST)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois Chicago
Multiple Sclerosis, Relapsing-Remitting, Fatigue
Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis
The goal of this clinical trial is to learn if repetitive Transcranial Magnetic Stimulation (rTMS) of the left premotor cortex can lessen fatigue in patients with Multiple Sclerosis, and if this is a feasible intervention.
- Trial name
- FANTiMS (NCT06569550)
- Testing
- Real Repetitive Transcranial Magnetic Stimulation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Research Centre for Magnetic Resonance
Stroke
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA.
- Trial name
- NCT07113990
- Testing
- Active EA, Active rTMS
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Jing Tao
Stroke
iTMS - Implementing Transcranial Magnetic Stimulation (TMS) to Assess Cortico-spinal Tract Integrity
Reliable prediction of upper limb (UL) function can guide clinicians in choosing relevant treatment, helps to set realistic goals for rehabilitation and will contribute to personalized and effective rehabilitation.
- Trial name
- iTMS (NCT06153017)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Psychotic Disorders
Magnetic Seizure Therapy for Psychotic Disorders
This trial aims to evaluate the efficacy and safety of Magnetic Seizure Therapy (MST) as an augmentation of antipsychotic medications for psychosis.
- Trial name
- NCT06581302
- Testing
- Magnetic seizure therapy by Magnetic stimulator, Antipsychotic medications (such as olanzpine, risperidone, aripiprazole, quetiapine, amisulpride, etc)
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Schizophrenia
Low and High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Resistant Auditory Hallucination in Schizophrenia
Auditory Hallucinations (AH) are experienced by 50 to 70% of subjects with schizophrenia. Almost a quarter of patients are medication resistant to such symptoms.
- Trial name
- rTMS (NCT02175251)
- Testing
- high frequency (20Hz), low frequency (1Hz)
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Muscle
Sensitivity and Reproducibility of 18F-fluorodeoxyglucose Positron Emission Tomography for Assessment of Respiratory Muscle Activity
The assessment of respiratory muscle function is critical within both clinical and research settings. Tools for the assessment of respiratory muscle function are especially useful in diagnosing, phenotyping, understanding…
- Trial name
- ResPET (NCT05234099)
- Testing
- 18F-FDG Positron emission tomography - MRI, Multiparametric ultrasound imaging, Surface electromyography
- Where
- 2 sites in France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Institut de Myologie, France
Arrhythmias, Cardiac
Study to Monitor Patients With Pacemakers or ICDs Who Undergo MRI Scans
This study is a prospective, non-randomized, unblinded case series of patients with permanent pacemakers and implantable cardioverter-defibrillators undergoing medically-required magnetic resonance imaging (MRI) scanning, at St.
- Trial name
- NCT01999751
- Testing
- MRI Scan
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Essentia Health
Aortic Coarctation, Arterial Stiffness
Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment
Background: Coarctation of the aorta (CoA) can be treated using surgery, balloon angioplasty or stent implantation. Although short-term results are excellent with all three treatment modalities, long term cardiovascular (CV)…
- Conditions
- Aortic Coarctation, Arterial Stiffness, PULSE WAVE VELOCITY, Functional Magnetic Resonance Imaging
- Trial name
- LOVE-COARCT (NCT03262753)
- Testing
- Surgery, Balloon dilation, Stent
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Spinal Cord Injury
Effects of Transcranial Magnetic Stimulation in Incomplete Spinal Cord Injury
The main objective is to conduct a study protocol to investigate the effects of repetitive Transcranial Magnetic Stimulation (rTMS) on sensory and motor performance of individuals with incomplete spinal cord injury (iSCI) .
- Trial name
- NCT02899637
- Testing
- Active high-frequency Transcranial Magnetic Stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Endocrine System Disease, Cardiovascular Imaging
Cardiac Steatosis in Cushing's Syndrome
This study aims at evaluating the myocardial triglyceride content and cardiac structure and function, using 1H magnetic resonance spectroscopy and cardiac magnetic resonance imaging, in patients with Cushing's syndrome before and…
- Trial name
- CORTICOEUR (NCT02202902)
- Testing
- 1H magnetic resonance spectroscopy and CMRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive Compulsive Disorder
Study of Magnetic Brain Stimulation in Treatment of Obsessive Compulsive Disorder
In a preliminary pilot study, the investigators tested the efficacy of rTMS over the medial prefrontal cortex in symptom profiles of obsessive compulsive disorder (OCD) patients.
- Trial name
- rTMS (NCT02018185)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Cocaine Use Disorder
Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)
The purpose of this study is to assess the effects of active intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal cortex (dmPFC) on electroencephalogram (EEG) measures of reward sensitivity and cue reactivity and…
- Trial name
- NCT05631548
- Testing
- iTBS to dmPFC
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The University of Texas Health Science Center, Houston
Type1diabetes, Depressive Symptoms
Type 1 Diabetes and Depression: Role of Brain Glutamate
The goal of this study is to examine the effect of chronic and acute hyperglycemia in type 1 diabetes mellitus (T1DM) on brain glutamate levels using magnetic resonance spectroscopy (MRS), and associations of brain glutamate with…
- Conditions
- Type1diabetes, Depressive Symptoms, Major Depressive Disorder
- Trial name
- NCT05355285
- Testing
- Glucose Clamp
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy Male Volunteers
Safety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101
The XEN1101 Phase 1 clinical trial is a randomized, double-blind, placebo-controlled study that will eventuate the safety, tolerability, pharmacokinetics (PK) and effects on transcranial magnetic stimulation (TMS) of oral doses…
- Trial name
- NCT03468725
- Testing
- XPF-008, Microcrystalline Cellulose
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Congenital Heart Disease, Hypoplastic Left Heart Syndrome
Erythropoetin Neuroprotection for Neonatal Cardiac Surgery
Brain problems occur in neonatal open heart surgery with a frequency of 20-70%, seen on neurological examination, brain imaging such as magnetic resonance imaging (MRI), or long term development problems such as learning…
- Conditions
- Congenital Heart Disease, Hypoplastic Left Heart Syndrome, Transposition of the Great Arteries, Aortic Arch Hypoplasia or Interruption
- Trial name
- NCT00513240
- Testing
- Erythropoetin, Normal saline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Baylor College of Medicine
Treatment Resistant Depression, Nitrous Oxyde
Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)
Recent evidence suggest that Nitrous Oxyde (N2O) could exhibit antidepressant effect in treatment-resistant depression (TRD). However, the pathophysiology of this effect remains unclear and could include glutamatergic activity…
- Trial name
- NCT04199143
- Testing
- Nitrous Oxide-Oxygen, Tissue Pulsatility Imaging - TPI, Magnetic Resonance Imaging - MRI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Glioblastoma
Evaluation of FLT PET and MRI as Imaging Biomarkers of Early Treatment Response in Patients With Glioblastoma
Glioblastoma is the most common primary malignant neoplasm of the adult brain. Even after multimodal therapy, outcomes remain poor, with a median survival of one year.
- Trial name
- NCT01880008
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Washington University School of Medicine
Brain Neoplasms
MR Elastography in Intracranial Lesions: Feasibility & Accuracy
Brain tumors, despite their relatively low incidence among cancers, are associated with high morbidity and mortality due to the brain's complexity.
- Trial name
- NCT06916715
- Where
- China
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Depersonalization Disorder
Depersonalization Disorder: Therapeutic Effect of Neuronavigated Repetitive Transcranial Stimulation
The purpose of this study is to assess the therapeutic efficacy of transcranial magnetic stimulation in patients with depersonalization disorder.
- Trial name
- PERSONA (NCT02476435)
- Testing
- Active rTMS
- Where
- 2 sites in France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
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