Clinical trials: Magnetism
Multiple Sclerosis
Validation and Standardization of Paramagnetic Rim Lesion (PRL) Identification in Multiple Sclerosis Across MAGNIMS Centers
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. Paramagnetic rim lesions (PRLs) are a subtype of chronic active MS lesions showing an iron-laden inflammatory rim on…
- Trial name
- NCT07705581
- Where
- 15 sites in Austria, Czechia and 9 more
- Volunteers
- 1,402 people
- Sponsor
- IRCCS San Raffaele
ST-segment Elevation Myocardial Infarction
Distal Protection Device in ST-elevation Myocardial Infarction (STEMI)
The investigators examined the mechanism underlying the lack of benefit from distal protection and thrombus aspiration (DP-TA) in 126 patients with ST-elevation Myocardial Infarction (STEMI) in a prospective, randomized trial.
- Trial name
- NCT01384019
- Testing
- distal protection and thrombus aspiration (The GuardWire Plus (Medtronic Inc.)), c-PCI
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Bundang Hospital
Depression, Unipolar
Intermittent Theta-burst Stimulation for Major Depression: an Intensity-response Study
The United States Food and Drug Administration (FDA) approved intermittent theta-burst stimulation (iTBS) in 2018 as a form of repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- NCT06392867
- Testing
- intermittent theta-burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 246 people
- Sponsor
- The Hong Kong Polytechnic University
Amyotrophic Lateral Sclerosis
New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a disabling and rapidly progressive neurodegenerative disorder. There is no treatment that significantly slows progression.
- Trial name
- IRM-SLA (NCT04691011)
- Testing
- Muscular MRI, Electrophysiological exam, Brain MRI
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
STEMI
Cardiovascular Magnetic Resonance Guided Open Artery Trial for Revascularization of Late Presenting ST Elevation Myocardial Infarction
Patients with STEMI are usually treated with primary PCI in contemporary practice. However, primary PCI is currently deemed unbeneficial or potentially harmful in patients presenting late after a STEMI.
- Trial name
- CRM-OAT (NCT05374265)
- Testing
- Cardiovascular Magnetic Resonance Scan
- Where
- United Kingdom
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Amyotrophic Lateral Sclerosis
Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2
Stage 1 [Enrolment closed]: The goal of this open-label pilot clinical trial is to evaluate the safety and feasibility of accelerated, repetitive transcranial magnetic stimulation (rTMS) using continuous theta-burst stimulation…
- Trial name
- QuARTS-ALS (NCT05983211)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Lateral Epicondylitis
Effects of Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With Lateral Epicondylitis
Lateral epicondylitis (LE) is one of the most frequently encountered lesions affecting the upper extremity and is the most common cause of elbow pain in adults.
- Trial name
- NCT04829734
- Testing
- Active PBMT-sMF
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- University of Nove de Julho
Schizophrenia
Best Event Schizophrenia Trial--A Randomized Double-Blind Trial of Aripiprazole and Risperidone in Schizophrenia
This study is being conducted to find a way to predict how individual schizophrenic patients will respond if they are treated with different types of antipsychotic drugs.
- Trial name
- BEST (NCT00712270)
- Testing
- Aripiprazole, Risperidone
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kettering Health Network
Transcranial Magnetic Stimulation, Freezing of Gait
Dual-target, High-dose TMS for PD Patients With FOG
The aim of the current study was to verify whether high-dose TMS treatment of the motor and cognitive cortices is more effective in alleviating FOG than conventional-dose TMS of the motor cortex only.
- Trial name
- NCT05625386
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Anhui Medical University
Magnetic Resonance Imaging, Pregnancy
Non-contrast 3D MR Angiography for Assessment of the Thoracic Aorta in Pregnancy
Introduction: Native magnetic resonance angiography (MRA) is recommended to assess the thoracic aorta during pregnancy, avoiding the risks of ionising radiation and contrast agent administration.
- Trial name
- NCT02793570
- Testing
- observational
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Primary Hyperthyroidism
Localization of Parathyroid Adenoma by Fluorocholine PET/MRI (Positron Emission Tomography -MRI)
A comparative prospective study to evaluate different imaging modalities (pet-ct and pet-mr) prior to surgery in parathyroid tumor patients.
- Trial name
- NCT02843542
- Testing
- PET-MR, PET-CT
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assuta Medical Center
ADHD
A Randomized, Double-blind, Sham-controlled Pilot Study to Evaluate the Treatment Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in College Students With ADHD
This pilot study is a randomized, double-blind, sham-controlled study designed to evaluate the efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in college students with ADHD. A total of 40 subjects will be treated.
- Trial name
- MeRT-USC-009 (NCT03066505)
- Testing
- Active MeRT Treatment
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Wave Neuroscience
Cystic Fibrosis, Gastrointestinal Dysfunction
Understanding Gut Symptoms in People With Cystic Fibrosis
Although chest infections affect wellbeing and survival in cystic fibrosis (CF), most people with CF also have difficulty digesting food and must take medication for this.
- Trial name
- GRAMPUS-CF SRC (NCT05934656)
- Testing
- Latent class analysis
- Where
- United Kingdom
- Volunteers
- 350 people
- Sponsor
- University of Nottingham
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma
This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with…
- Conditions
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Trial name
- NCT01825902
- Testing
- fluorine F 18 fluorothymidine, fludeoxyglucose F 18, positron emission tomography
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Focal Vibration, Electroencephalography
The Effects of Focal Muscle Vibration Combined With Exercise on Sensorimotor Activity in Individuals With Chronic Subacromial Impingement Syndrome
Background: Subacromial impingement syndrome (SIS) is a common shoulder disorder characterized by pain, altered movement patterns, and functional impairment.
- Conditions
- Focal Vibration, Electroencephalography, Transcranial Magnetic Stimulation, Somatosensory Dysfunction
- Trial name
- NCT06694402
- Testing
- focal muscle vibration combined with exercise, exercise
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Yang Ming Chiao Tung University
Hereditary Hemorrhagic Telangiectasia
MRA With Feraheme in HHT
Magnetic resonance (MR) imaging is performed with contrast agents to highlight the blood vessels and allow interpretation and diagnosis of blood vessel abnormalities.
- Trial name
- NCT02977637
- Testing
- Feraheme MRI/MRA
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Alzheimer Disease, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer Disease
Randomized clinical trial, comparative and single blind aims to determine effects on cognition, psychological and behavioral symptoms and functionality of 5 Hz repetitive transcranial magnetic stimulation (rTMS) administered over…
- Trial name
- AD-EMTr (NCT03270137)
- Testing
- repetitive transcranial magnetic stimulation- IDLPFC, repetitive transcranial magnetic stimulation - Six regions
- Volunteers
- 19 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Depression
The Study About Mechanism of Transcranial Magnetic Stimulation Treatment of Depression Using Medical Imaging
Depression is the most common psychiatric condition and a important public health concern in society. But medications for depression don't work as well as people expected and cause serious side-effects.
- Trial name
- NCT03500029
- Testing
- Transcranial magnetic stimulation (TMS), antidepressants
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Medullary Sponge Kidney
Multiparametric Magnetic Resonance Imaging (MRI) in Medullary Sponge Kidney
Background : Medullary sponge kidney disease is a congenital disorder caracterised by tubular ectasia and cystic dilatation of the collecting ducts in the pericalyceal region of the renal pyramids, which can lead to…
- Trial name
- MICARI (NCT05682053)
- Testing
- Multiparametic MRI
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Mild Cognitive Impairment
Comparison of Two Non-invasive Neuromodulation Techniques as Synergistic Therapy to Cognitive Stimulation in Amnestic Mild Cognitive Impairment (aMCI)
This is a comparative, double-blind, randomized controlled clinical trial for people with Amnestic Mild Cognitive Impairment. The investigators will compare the effects of two non-invasive neuromodulation techniques (Repetitive…
- Trial name
- NCT06467253
- Testing
- 1. rTMS + CS, 3. tDCS + CS
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
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