Clinical trials: Magnetism
Hypoxic Ischemic Encephalopathy
Magnetic Resonance Imaging and Spectroscopy Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy
Neonatal hypoxic ischemic encephalopathy (HIE) is a serious neurological condition characterised by acute or subacute brain injury arising from perinatal hypoxia.
- Trial name
- NCT01481207
- Where
- Switzerland
- Volunteers
- 59 people
- Sponsor
- University Children's Hospital, Zurich
Essential Tremor
Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor
Pathophysiology of tremor-modulating mechanisms of propranolol and primidone in essential tremor (ET) will be studied using accelerometry with electromyography (EMG), transcranial magnetic stimulation (TMS), and eyeblink…
- Trial name
- NCT04692844
- Testing
- Propranolol, Primidone
- Where
- Slovenia
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Prostate Cancer (Diagnosis)
Evolution of Lesions in Repeated Biparametric Prostate Magnetic Resonance Imaging
The goal of this clinical trial is to prospectively investigate the evolution of lesions in biparametric magnetic resonance imaging (bpMRI) of the prostate in men with no clinically significant prostate cancer (csPCa) in their…
- Trial name
- REMRI (NCT07369570)
- Testing
- MRI
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Eastern Finland
Cervical Spondylosis With Myelopathy, Degenerative Cervical Myelopathy
Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy
To use advanced imaging techniques, including MRI Brain and Spinal Cord, and MRI/PET Spinal Cord to provide an assessment of Degenerative Cervical Myelopathy to improve understanding of the pathophysiology and natural history of…
- Trial name
- IMAGE-DCM (NCT05242666)
- Testing
- 3T MR Imaging of the cervical spinal cord, Positron Emission Tomography using [11C]PIB, 3T MR Imaging of the Brain
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Irritable Bowel Syndrome, Colonic Diseases, Functional
fMRI and Visceral Perception Upon Capsaicin Infusion
Brain imaging has shown abnormal brain activations in response to visceral stimulation in patients with the Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD).
- Conditions
- Irritable Bowel Syndrome, Colonic Diseases, Functional, Dyspepsia, Gastrointestinal Diseases
- Trial name
- NCT02551029
- Testing
- Capsaicin
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Multiple Sclerosis, Depression, Anxiety
iTBS Study for Depression in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic and demyelinating disease of the central nervous system. It is one of the most common cause of neurological disability in young adults.
- Trial name
- NCT04524039
- Testing
- intermittent theta burst stimulation using a MagPro X100
- Volunteers
- 30 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping
Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping: A Cross Sectional Observational Study
Three-Dimensional Ultrasonography versus Magnetic Resonance Imaging for Fibroid Mapping: A Cross sectional Observational study
- Trial name
- NCT05505331
- Testing
- three-Dimensional ultrasonography, Magnetic resonance imaging, myomectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Chemotherapy-induced Peripheral Neuropathy
Use of Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy
The study aims to evaluate the feasibility of a repetitive transcranial magnetic simulation (rTMS) protocol developed for managing pain and other related symptoms associated with chemotherapy-induced peripheral neuropathy in…
- Trial name
- NCT04107272
- Testing
- Real repetitive transcranial magnetic stimulation
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Post Concussive Syndrome, Chronic, Post Concussion Symptoms
Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome
This study looks at the effects of accelerated intermittent theta burst stimulation (aiTBS) on patients with chronic and acute post-concussion syndrome.
- Conditions
- Post Concussive Syndrome, Chronic, Post Concussion Symptoms, Post Concussive Syndrome, Post Concussion Syndrome
- Trial name
- NCT07211919
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cognitive FX
Alcohol Use Disorder, Smoking
Alcohol and Cigarette Craving During Oxytocin Treatment
This proposed research seeks to examine the behavioral and neural substrates of intranasal oxytocin compared to placebo on alcohol cue-induced alcohol and cigarette craving smokers with an alcohol use disorder (AUD).
- Trial name
- NCT04071119
- Testing
- Oxytocin nasal spray
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Brown University
Cardiomyopathy, Dilated, Tachycardia, Ventricular
The Leiden Nonischemic Cardiomyopathy Study
Rationale: Sudden cardiac death, mainly caused by ventricular arrhythmias (VA), is a major cause of morbidity and mortality in non-ischemic cardiomyopathy (NICM). Therapies that effectively prevent VA are lacking.
- Conditions
- Cardiomyopathy, Dilated, Tachycardia, Ventricular, Ventricular Fibrillation
- Trial name
- NCT01940081
- Testing
- Transthoracic echocardiography, Exercise test, 24-hour Holter electrocardiogram
- Where
- Netherlands
- Volunteers
- 148 people
- Sponsor
- Leiden University Medical Center
Transcranial Direct Current Stimulation, Anxiety
Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Anxiety Disorder
To investigate the intervention effect of high definition transcranial direct current stimulation (HD-tDCS) on anxiety symptoms and somatic symptoms in patients with anxiety disorder and its underlying neural mechanism by MRI.
- Conditions
- Transcranial Direct Current Stimulation, Anxiety, Magnetic Resonance Imaging
- Trial name
- NCT05298007
- Testing
- High definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
End Stage Renal Disease
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
Frailty and sarcopenia are modifiable risk factors for morbidity and mortality in patients with ESRD. Exercise is the recommended intervention to prevent frailty and sarcopenia, however, many clinical trials have shown limited…
- Trial name
- NCT05422534
- Testing
- CoQ10, HB-HIIT, Observational
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Vanderbilt University Medical Center
Depression - Major Depressive Disorder
Tidal Model-Based ACT for Depression
The purpose of this randomized controlled clinical trial is to evaluate the effectiveness of an Acceptance and Commitment Therapy (ACT)-oriented psychoeducation program based on the Tidal Model in patients diagnosed with…
- Trial name
- TIDAL-ACT (NCT07442253)
- Testing
- Tidal Model-based ACT
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Baskent University
Acute Myocardial Infarction (AMI)
Early CMR in Acute MI
The goal of this observational study is to evaluate the clinical utility of cardiac magnetic resonance (CMR) in patients with acute myocardial infarction (AMI).
- Trial name
- Early AMI-CMR (NCT07602439)
- Testing
- Cardiac magnetic resonance imaging
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Diabetic Kidney Disease
Prognostic Imaging Biomarkers for Diabetic Kidney Disease
Diabetic kidney disease (DKD) is a common complication of diabetes, and is now the most common form of chronic kidney disease. DKD is the leading cause of kidney disease requiring dialysis or kidney transplantation, and its…
- Trial name
- iBEAt (NCT03716401)
- Testing
- MRI (magnetic resonance imaging), US (ultrasound), Renal Biopsy
- Where
- 7 sites in Finland, France and 4 more
- Volunteers
- 500 people
- Sponsor
- University of Leeds
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT05045820
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
Central Cord Syndrome
The Natural History of Traumatic Spinal Cord Injury Using fMRI, MRS and DTI
Traumatic spinal cord injury is a common injury to the spine and can lead to a clinical syndrome called central cord syndrome (CCS).
- Trial name
- NCT00790361
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Transcranial Magnetic Stimulation, Complex Regional Pain Syndrome of Upper Limb (Disorder)
CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation
This is a sham controlled, randomized, double-blind, navigated repetitive Transcranial Magnetic Stimulation (nrTMS) study for the treatment of complex regional pain syndrome (CRPS types 1 and 2).
- Trial name
- NCT04439669
- Testing
- Active nrTMS and open phase
- Where
- 2 sites in Finland
- Volunteers
- 62 people
- Sponsor
- Helsinki University Central Hospital
Tremor, Essential, Parkinson's Disease
Mapping the Target for the MRgFUS Treatment of Tremor
The purpose of this investigation is to determine the optimal DRT/VIM target location and its safety margins based on MR-SISET imaging features by comparing with postoperative lesions and clinical outcomes in patients with tremor…
- Trial name
- NCT04661241
- Testing
- Automatic DRT/VIM target-recognition method using MR-SISET and ML approaches, Routine clinical MRI protocol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
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