Clinical trials: Magnetism
Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis
Ultrasound-Based Liver Fat Quantification (LFQ) Pilot Study
This clinical study will involve performing a series of medical imaging procedures of the abdomen using both ultrasound and MRI modalities in subjects at risk for or already diagnosed with Nonalcoholic Fatty Liver Disease…
- Trial name
- LFQ (NCT04657523)
- Testing
- Investigational Liver Fat Quantification Software
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Depression, Bipolar
Combined Cytidine and Creatine-containing Drug in the Treatment of the Bipolar Depression
This research is aimed to investigate the efficacy and safety of the creatine and cytidine augmentation in treating bipolar depression and to evaluate changes in relevant brain biochemical metabolism using proton and phosphorous…
- Trial name
- NCT02625779
- Testing
- Valproate and Cytidine-containing Drug, Valproate and Creatine-containing Drug
- Where
- South Korea
- Sponsor
- Ewha Womans University Mokdong Hospital
Human Body Composition, Human Body Function
Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications
The purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body
- Trial name
- MRS VALIDATION (NCT02663362)
- Testing
- To evaluate the reproducibility of acquiring multi-nuclear data on a new 3T Philips Magnet
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Pancreatic Neoplasms, Pancreatitis, Chronic
Magnetic Compressive Technique for Pancreatic Intestinal Anastomosis
In recent five years, the investigators have successfully developed different types of magnets and utilized in biliojejunostomy, concomitant biliojejunostomy and pancreaticojejunostomy during Whipple.
- Trial name
- MCTPIA (NCT03780946)
- Testing
- Magnetic anastomosis for pancreaticojejunostomy, Traditional hand-sewn anastomosis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Depression
A Clinical Trial of Magnetic Stimulation in Depression
The purpose of this study is to determine whether repetitive high field transcranial magnetic stimulation of the left or right frontal lobes is beneficial for the treatment of depression that is refractory to antidepressant…
- Trial name
- NCT00711568
- Testing
- Repetitive transcranial magnetic stimulation (rTMS), Repetitive Transcranial Magnetic Stimulator
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Healthy
Effects of tDCS Over the Cerebellum on Motor Function
This study will evaluate whether applying electrical stimulation on the cerebellum (posterior and lower part of the brain) can influence brain excitability and hand movement performance.
- Trial name
- NCT00413842
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neuroinflammation, Autism Spectrum Disorder
Imaging - Clinical Evaluation of Altered Nervous System Drainage
The current study aims to evaluate the aspects of perfusion, fluid diffusivity in the interstitium and the T1 and T2 signal of the PVS and WMH.
- Trial name
- I-CLEANED (NCT06432023)
- Testing
- Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis
The DanNORMS study is a phase 3, non-inferiority clinical trial examining whether treatment of active multiple sclerosis with rituximab is non-inferior to ocrelizumab regarding efficacy and safety.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis
- Trial name
- DanNORMS (NCT04688788)
- Testing
- Rituximab, Ocrelizumab, Fexofenadine
- Where
- 11 sites in Denmark
- Volunteers
- 600 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tourette Syndrome
Transcranial Magnetic Stimulation for Children With Tourette's Syndrome
Tics are the core symptom of Tourette syndrome. These are repetitive, sudden, semi-voluntary movements or sounds. In some children, these tics can be especially bad and require treatment, however, options are limited.
- Trial name
- TICS (NCT02356003)
- Testing
- Low frequency repetitive transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy
Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response
Every year, approximately 2 million people in the United States and 280,000 in Canada experience a mild traumatic brain injury/concussion.
- Conditions
- Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy, Post-Concussion Syndrome, Concussion
- Trial name
- NCT04568369
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Calgary
Pediatric Obesity
Neural Mechanisms Underlying Children's Responses to Food Portion Size and Energy Density
Increased portion sizes of foods high in energy density (calories per gram of food) have been implicated in the obesity epidemic.
- Trial name
- NCT02759523
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Penn State University
Prostate Cancer
Long-term Outcomes of Prostate Cancer Screening
This study is an expansion of the screening-by-invitation STHLM3MRI trial for detection of prostate cancer. In summary, we assess longterm outcomes (prostate cancer mortality, incidence and resource use) in men (i) invited and…
- Trial name
- STHLM3MRI_3 (NCT07155759)
- Testing
- PSA/Stockholm3/MRI, PSA
- Where
- Sweden
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
End-stage Renal Disease, Left Ventricular Hypertrophy
In-Centre Nocturnal Hemodialysis (INHD): A Long-Term Follow-Up Study
Background: In 2010, approximately 39000 Canadians had end-stage renal disease (ESRD), and the prevalence rate of dialysis has increased by 189% over the past 2 decades.
- Trial name
- INHD (NCT02684773)
- Testing
- Conventional Hemodialysis, In-centre Nocturnal Hemodialysis
- Where
- 2 sites in Canada
- Volunteers
- 67 people
- Sponsor
- Unity Health Toronto
Spondyloarthritis, Spondylarthropathy
Assessment of SpondyloArthritis Society (ASAS) Classification and Diagnostic Criteria for Early Axial Spondyloarthritis (SpA)
Background: Existing criteria for AS/SpA such as mod. New York, ESSG, or Amor criteria for classification and/or diagnosis of spondyloarthritis have limitations when applied to early disease.
- Conditions
- Spondyloarthritis, Spondylarthropathy, Spondylitis, Ankylosing
- Trial name
- NCT00328068
- Where
- 35 sites in United States, Belgium and 18 more
- Volunteers
- 992 people
- Sponsor
- Charite University, Berlin, Germany
Obesity, Weight Loss
Lorcaserin in Obesity: Identification of CNS Targets Using fMRI
The purpose of this protocol is to investigate, using functional magnetic resonance imaging (fMRI), the effect of treatment with lorcaserin on centers of the brain that control appetite and food intake, as well as lorcaserin's…
- Trial name
- NCT02400359
- Testing
- Lorcaserin HCl
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Alzheimer's Disease
The Locus Coeruleus and Memory
The cause of Alzheimer's disease, the most common form of dementia, remains unknown. Neuropathological studies suggest that a small area in the brainstem, the locus coeruleus, might be the site of the onset of the disease.
- Trial name
- LOCUS (NCT02363504)
- Testing
- 7 Tesla MRI with memory task and non-invasive neurostimulation
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Neuropathic Pain, Cortical Excitability
Analysis of Cortical Excitability in Neuropathic Pain
The purpose of this study is to determine whether patients with neuropathic pain has abnormal excitability in somatosensory cortex and abnormal sensory-motor connections.
- Trial name
- NCT00789347
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Safety of MRI
Safety of Magnetic Resonance Imaging With Patients Who Have Mixed Lead Cardiac Implantable Electronic Devices
This study is looking at the safety and efficacy of using MRIs with patients who have cardiac implantable electronic devices.
- Trial name
- MRIMLD (NCT07155135)
- Testing
- MRI
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Socal Heart
Neurofibromatosis Type 1, Precancerous Condition
Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma
RATIONALE: New imaging procedures such as fludeoxyglucose F 18 positron emission tomography (FDG-PET) and magnetic resonance (MR) perfusion imaging may improve the ability to detect disease progression, help doctors predict a…
- Trial name
- NCT00060008
- Testing
- fludeoxyglucose F 18, gadopentetate dimeglumine
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Movement Disorders, Heathly Subjects
Changes in the Posterior Parietal Cortex - Primary Motor Cortex Pathway Induced by Motor Training
Objective When learning to tap to a rhythm the brain has to coordinate information from different senses (eyes, ears, touch). This information has to be integrated into a movement plan to allow a smooth, continuous performance.
- Trial name
- NCT00904332
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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