Clinical trials: Maintenance
Substance Use Disorders
Cognitive Stimulation
This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking.
- Trial name
- NCT01271413
- Testing
- Computerized cognitively stimulating activities
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anesthesia
Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?
To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.
- Trial name
- NCT03806374
- Testing
- Ketamine, Propofol, Fentanyl
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Depressive Disorder, Anxiety Disorders
Happy Nurse Project: Lifestyle Interventions to Maintain Healthy Mental State in Hospital Nurses
The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses.
- Trial name
- HNP (NCT02151162)
- Testing
- Mindfulness-based stress management program, Omega-3 fatty acids pills, Psychoeducation leaflet
- Where
- 2 sites in Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Center of Neurology and Psychiatry, Japan
Cognitive Function
Promoting Mental Acuity in Elderly Populations Through Incentive for Technology Use
In this between-subject randomized controlled trial the investigators will test the impact of three novel structured financial incentives: atomistic, altruistic and team-based.
- Trial name
- NCT00805259
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Coronary Heart Disease, Obesity
Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection
The proposed research will demonstrate that alternate day modified fasting (ADMF) is a suitable alternative to daily calorie restriction (CR) for weight loss, weight maintenance, and heart disease prevention.
- Conditions
- Coronary Heart Disease, Obesity, Weight Loss
- Trial name
- NCT00960505
- Testing
- Alternate day fasting, Calorie restriction, Control diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Colorectal Cancer
Cetuximab Monotherapy Maintenance Treatment in mCRC
Investigating the efficacy of Cetuximab Monotherapy versus Continuation after induction treatment with chemotherapy + Cetuximab in inoperable or irresectable and non-progressive metastatic colorectal cancer after first line…
- Trial name
- NCT02978313
- Testing
- Cetuximab, mFOLFOX6, FOLFIRI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Sleep Quality, Fatigue
The EMS Sleep Health Study: A Randomized Controlled Trial
The experiment seeks to determine the impact of a sleep health and fatigue education and training program on diverse indicators of sleep and fatigue among Emergency Medical Services (EMS) personnel.
- Trial name
- NCT04218279
- Testing
- Sleep Health Education
- Where
- United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Insomnia
Effectiveness and Adherence to an Online Sleep Program
This research will examine the effectiveness of a 6-week online sleep program (Go! To Sleep) which provides a set of various psycho-educational materials and behavioral techniques to reduce insomnia symptoms, improve sleep, and…
- Trial name
- NCT01440777
- Testing
- Go! to Sleep
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Depression Anxiety Disorder, Sleep Quality
Digital Silence and Mental Health
Social media use has been linked to negative mental health outcomes, including increased anxiety, depression, stress, poor sleep quality, and difficulties in emotion regulation.
- Trial name
- NCT07147829
- Testing
- digital detox
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Insomnia
Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication
Sleep related disorders are common in primary care practice. Sleep wear related data has not been utilized to improve sleep related communication between patients and providers.
- Trial name
- NCT03795129
- Testing
- SleepLife Application w/FitBit, FitBit w/Minimal to No SleepLife App.
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Regenstrief Institute, Inc.
Insomnia
the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets
Multiple Dose Safety, Tolerability, PK ，PD and Food Effect Study of HEC83518 in Healthy Subjects
- Trial name
- NCT04667429
- Testing
- Food, HEC83518
- Where
- China
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Sedentary Time, Insomnia
mPATH for Low-income Older Adults
Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults.
- Conditions
- Sedentary Time, Insomnia, Cognitive Decline
- Trial name
- NCT05935241
- Testing
- mPATH, Attention Control
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Plasmodium Malariae Infection, SMC
Impact of Seasonal Malaria Chemoprevention on Immunity Against Malaria Among Children in Northern Benin
This study aims to evaluate the effects of SMC (Seasonal malaria chemoprevention) with Sulfadoxine-Pyrimethamine (SP) and Amodiaquine (AQ) on the evolution of anti-malarial immunity of children and their susceptibility to…
- Conditions
- Plasmodium Malariae Infection, SMC, Immune System Disease
- Trial name
- ISAMIMA (NCT05650502)
- Testing
- saisonal malaria chimoprevention
- Where
- Benin
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Université de Parakou
Effect of Insomnia and Sleep Deprivation in 3rdtrimester
Effect of Clinical Insomnia and Sleep Deprivation on Maternal-fetal Outcome Among Egyptian Females in 3rd Trimester
This prospective observational study aims at investigating whether insomnia or sleep deprivation during the 3rd trimester of pregnancy can be implicated in the occurrence of adverse maternal or fetal outcome.
- Trial name
- NCT04612361
- Testing
- insommnia severity index questionnaire
- Where
- Egypt
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Dr. Osman Hospital
Quality of Life, Insomnia
The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health
Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based…
- Conditions
- Quality of Life, Insomnia, Depression, Anxiety
- Trial name
- NCT05394753
- Testing
- Unified Protocol for mood disorders
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Bruxism, Posture
Determining the Relationship Between Posture, Muscle Stiffness, Pain, and Jaw Functionality in Individuals With Bruxism
Bruxism is a repetitive jaw-muscle activity characterized by teeth clenching and/or grinding, often associated with temporomandibular joint dysfunction, pain, and impaired jaw function.
- Conditions
- Bruxism, Posture, Sleep Quality, Pain Assessment
- Trial name
- Bruxism (NCT07560670)
- Testing
- Bruxism Assessment Form, Clinical Examination, Patient Evaluation Form
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Healthy Older Adults
Neural Representations of Memory Transformation (MEM_TRANS)
Investigators overarching goal is to provide evidence for the link between altered spatiotemporal (where and when) neural mechanisms and the extent of changed memory maintenance in healthy older adults and to identify potential…
- Trial name
- NCT06862622
- Testing
- Computer-based visuomotor sequence learning and interference
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Gingivitis
Evaluation of Two Active Lactobacilli for the Maintenance of Gingival Health
The objective of the study will be to demonstrate the effects of two active lactobacilli (A/B) and determine whether there are any changes in plaque accumulation, gingival health, immunological and microbial markers compared to a…
- Trial name
- NCT03291327
- Testing
- Probiotics
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
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