Clinical trials: Maintenance
Tobacco Use Disorder
Maintenance Treatment for Abstinent Smokers
The purpose of this study is to determine the efficacy and cost-effectiveness of long-term pharmacotherapy (using Zyban and/or nicotine replacement) for reducing the relapse rate associated with stopping smoking.
- Trial name
- NCT00063323
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Aging, Sarcopenia
Mycoprotein as the Basis of a Sustainable Diet to Support Muscle Mass Maintenance and Reconditioning in Older Adults.
A hallmark of ageing is loss of skeletal muscle mass and strength (sarcopenia). Sarcopenia is explained, partially, by reduced responsiveness of muscle to dietary protein.
- Trial name
- MASS (NCT04325178)
- Testing
- Protein, calorie and macronutrient controlled diet, derived from either omnivorous or non-animal sources, alongside unilateral resistance exercise, over a three-day period.
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Muscle Disorder
Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms
To compare the effects of stretching exercises versus thermotherapy on RLS symptoms and sleep quality among pregnant women. Research hypotheses: Pregnant women who perform leg stretching exercises exhibit lower RLS symptoms…
- Trial name
- Exersize (NCT05261035)
- Testing
- stretching exercises, thermotherapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pain, Insomnia
Effect of Medical Marijuana on Neurocognition and Escalation of Use
This study will use a randomized controlled design to test whether patients who use medical marijuana, compared to a waitlist control group, experience a change in health outcomes (relief of symptoms, or adverse health outcomes…
- Conditions
- Pain, Insomnia, Depression, Anxiety
- Trial name
- MMNE (NCT03224468)
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment, Insomnia
Multicomponent Behavioral Sleep Intervention for Insomnia in Older Adults With Mild Cognitive Impairment
Insomnia symptoms in older adults with mild cognitive impairment represent a significant public health burden in terms of impaired quality of life, risks from untreated insomnia, and risks from pharmaceutical insomnia treatment.
- Trial name
- MBSI-I (NCT04364191)
- Testing
- Multicomponent Behavioral Sleep Intervention for Insomnia, Active Control
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
4-STEP-Training Program for Social Media Addiction
The Effectiveness of 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and Psychological Problems Among Adolescence
This study evaluates the effectiveness of the 4-STEP Training Program in reducing social media addiction and improving psychological well-being among adolescents.
- Trial name
- 4-STEP-TPS (NCT07564115)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Sleep Initiation and Maintenance Disorders
Behavioral and Pharmacological Treatment for Insomnia
This study will evaluate the long- and short-term effects of cognitive-behavior therapy (CBT), alone and in combination with zolpidem (Ambien®), for chronic insomnia.
- Trial name
- NCT00042146
- Testing
- Cognitive-behavior therapy, zolpidem
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laval University
Insomnia, Insulin Resistance
Insomnia and Insulin Resistance
Insomnia symptoms are linked to metabolic syndrome (MetS), which includes abnormal glucose metabolism, insulin resistance (IR), and incidence of diabetes. Chronic sleep deficit is a major predictor of disease and early mortality.
- Trial name
- NCT07333586
- Testing
- CBT-I, sleep hygiene
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
ELDERLY PEOPLE
Laughter Yoga is Role in Enhancing Sleep and Well-being in the Elderly
Objective: The study aims to evaluate the effects of Laughter Yoga on sleep quality, vitality, active aging, and quality of life in individuals aged 60 and over.
- Trial name
- NCT06685731
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Insomnia
Self-help Lifestyle Medicine for Insomnia
This study will examine the effects of a self-help smartphone-based multi-component lifestyle medicine intervention (LM) for alleviating insomnia symptoms in a Chinese population.
- Trial name
- NCT04703283
- Testing
- Lifestyle Medicine
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Vitamin D Deficiency
Determination of Vitamin D Dose to Maintain Sufficiency Amongst Indian and Malay Women in the Tropics
Much research on vitamin D status has focused on seasonal variations in serum 25(OH)D levels in populations living at high altitudes and those of light-skinned Caucasian extraction, with little work done in multi ethnic…
- Trial name
- NCT02389179
- Testing
- Vitamin D3
- Where
- Malaysia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sharifah Faradila bt Wan Muhamad Hatta
Cancer
Progressive Relaxation Exercise on Dyspnea, Pain and Sleep Quality
This study was planned to examine the effect of progressive relaxation exercises applied to lung cancer patients receiving chemotherapy on dyspnea, pain and sleep quality.
- Trial name
- Progressive (NCT04978805)
- Testing
- Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Mental Health Wellness 1
#Stayhealthy - Monitoring and Maintenance of Mental Health Under Conditions of Social Isolation During the Corona Crisis
The COVID-19 pandemic has led to a global health crisis with, so far, over 21 million registered cases and more than 700.000 deaths worldwide.
- Trial name
- stayhealthy (NCT04871386)
- Testing
- Acceptance and commitment therapy (ACT) exercises, Positive psychology (PP) exercises
- Where
- Germany
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Sleep Onset Insomnia
Effect of Background Noise on Sleep Quality
Insufficient and low-quality sleep is a major public health problem that has been linked to motor vehicle crashes, industrial disasters, and medical and other occupational errors.
- Trial name
- Noise (NCT02945254)
- Testing
- NIghtingale (R) device for filtered white noise (Cambridge Sound Management, Waltham, MA)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Glucocorticoid Effect
The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)
In a randomized, cross-over study, 20 healthy volunteers will receive a block and replace therapy that mimics physiological GC rhythm (metyrapone plus hydrocortisone) or placebo.
- Trial name
- NCT05919992
- Testing
- Metyrapone 250 mg Oral Tablets, Hydrocortisone 19.9mg s.c., pulsatile with a flow rate of 10μl/s
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eleonora Seelig
Severe Obesity
Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity
Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations involving appetite, satiety, and energy expenditure in the post- weight loss setting.
- Trial name
- NCT02496611
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dementia
Brief Behavioural Treatment for Insomnia in Dementia Carers
Background: between 50-74% of dementia carers report some sleep disturbance. However, relatively few studies have looked at psychological treatment for insomnia in this group.
- Trial name
- NCT02983032
- Testing
- BBTI
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Physical Inactivity
The Effect of Brain Breaks on People With Mental Health Problems
Regular physical activity (PA) and adopting an active lifestyle protect against non-communicable diseases such as diabetes, cardiovascular diseases, hypertension, obesity, and colon cancer in the general population.
- Trial name
- NCT05783674
- Testing
- Brain Breaks® Video Exercises, Posture training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istinye University
Restless Leg Syndrome
Effects of Static Stretching and Strength Training on Antenatal Restless Leg Syndrome
Restless Legs Syndrome (RLS) is a prevalent sensorimotor disorder affecting pregnant women, particularly in the third trimester, and is associated with sleep disturbances, fatigue and reduced quality of life.
- Trial name
- NCT07642089
- Testing
- Static Stretching, Static Stretching + Strength Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Complementary Alternative Medicine, Menopause
Therapeutic Touch and Foot Reflexology on Sleep Quality and Menopausal Symptoms
This randomized controlled trial was designed to compare the effects of therapeutic touch and reflexology on sleep quality and menopausal symptoms in postmenopausal women affected by the February 6, 2023 Kahramanmaraş…
- Conditions
- Complementary Alternative Medicine, Menopause, Sleep Disturbance
- Trial name
- NCT07767318
- Testing
- Therapeutic Touch, Foot Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University