Clinical trials: Maintenance Therapy
Menopause, Sleep Quality
Effect of Menopausal Hormone Therapy on Sleep
The Effect of Menopausal Hormone Therapy on Sleep (menoSLEEP) study is investigating the effects of menopausal hormone therapy (MHT) on sleep problems in peri- and postmenopausal women with an indication for MHT.
- Conditions
- Menopause, Sleep Quality, Psychological Wellbeing
- Trial name
- menoSLEEP (NCT07674316)
- Testing
- HRT
- Where
- Switzerland
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sleeping Efficacy, Sleep Quality
A Real-World Exploratory Study on the Sleep-Improving Efficacy of Dong'e Brand Ejiao Yuanjiang
This study employs a real-world design to evaluate the sleep-improving efficacy of Dong'e Brand Ejiao Yuanjiang. A total of 66 participants aged 25-55 will be enrolled and assessed after 60 days of continuous use.
- Trial name
- NCT07677709
- Testing
- Dong'e Brand Ejiao Yuanjiang
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Adult Women
Interoceptive Awareness and Dream Themes
Individual differences in reported dream themes may reflect not only waking emotional and cognitive experiences but also characteristic ways of attending to, interpreting, and regulating bodily signals.
- Trial name
- NCT07716514
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Primary Insomnia
A High Density EEG Comparison of Sleep Patterns in Insomnia
Insomnia, defined as a subjective report of difficulty initiating sleep, maintaining sleep, and/or non-restorative sleep, leads to significant daytime dysfunction and increased health risks.
- Trial name
- NCT01960452
- Testing
- Serial awakenings
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Occupational Health, Sleep
Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue
The U.S. registered nurse (RN) workforce is the largest in the Healthcare and Social Assistance Sector and is at high risk for injuries and errors due to poor sleep and fatigue.
- Conditions
- Occupational Health, Sleep, Fatigue, Nurse
- Trial name
- RN-SLEEP (NCT06105307)
- Testing
- RN-SLEEP, Healthy Habit - Educational Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Insomnia, Cognitive Disorder
Study on Cognitive Impairment of Insomnia Based on MRI
Insomnia is a common sleep disorder. In recent years, the incidence of insomnia is increasing worldwide. Studies point out that insomnia plays an important role in the pathogenesis of cognitive impairment.
- Conditions
- Insomnia, Cognitive Disorder, MRI
- Trial name
- NCT05659511
- Testing
- MRI
- Where
- China
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Post-Traumatic Stress Symptoms, Poor Sleep Quality
Psychoeducation-Supported Breathing and Relaxation for Earthquake Survivors
This randomized controlled study evaluated whether a structured program combining psychoeducation, breathing exercises, and relaxation techniques could reduce post-traumatic stress symptoms and improve sleep quality among adult…
- Trial name
- NCT07781904
- Testing
- Psychoeducation-Supported Breathing and Relaxation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rana Ceviz
Peri Implantitis
a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants
This aim of this study is to compare different oral hygiene aids for the ability to remove plaque in patients who went through dental implant treatment and are currently on a maintenance program at the Graduate Periodontal…
- Trial name
- NCT02091609
- Testing
- dental interproximal brush, dental floss
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Catheter Obstruction
Non-inferiority of Clinical Trials in Comparison With the Length of Totally Implemented Porth-a-Cath Maintenance From 60 Versus 90 Days
Abstract: Antineoplastic therapy (AT) is one of the most used treatment modalities to fight cancer, either curatively or palliatively.
- Trial name
- NCT05084040
- Testing
- 90 days interval between catheter maintenance
- Where
- Brazil
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- AC Camargo Cancer Center
Treatment Resistant Depression
Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine
This study aims to assess the efficacy and safety of intranasal esketamine as maintenance antidepressant therapy in patients who have demonstrated clinical improvement with off-label intravenous racemic ketamine for…
- Trial name
- NCT04856124
- Testing
- Intranasal esketamine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Psych Atlanta
Job Stress, Workplace Stress
Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness During the COVID-19 Pandemic
This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON.
- Conditions
- Job Stress, Workplace Stress, Compassion Fatigue, Psychological Trauma
- Trial name
- BREATH (NCT04368676)
- Testing
- Sudarshan Kriya Yoga (SKY), Health Enhancement Program
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dialysis Related Complication
Lower Dialysate Temperature and Post-Dialysis Fatigue
The standard dialysate temperature is usually set at 36.5°C in hemodialysis applications. Since this temperature is close to the patient's body temperature, it is ideal for preventing the patient from experiencing hypothermia…
- Trial name
- NCT07071376
- Testing
- cold dialysis
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Baskent University
Insomnia
SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid
The objective of this study is to compare the efficacy of a sleep intervention on improving cognitive function in older adults with symptoms of insomnia, determine the association between change in sleep measures and change in…
- Trial name
- NCT03954210
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Colorectal Cancer
Cetuximab Monotherapy Maintenance Treatment in mCRC
Investigating the efficacy of Cetuximab Monotherapy versus Continuation after induction treatment with chemotherapy + Cetuximab in inoperable or irresectable and non-progressive metastatic colorectal cancer after first line…
- Trial name
- NCT02978313
- Testing
- Cetuximab, mFOLFOX6, FOLFIRI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Smartphone Addiction, Students, Nursing
Motivational Interview Based Intervention Program on Smartphone Addiction and Sleep Quality
Smartphones are the technological devices of our age that are constantly evolving and whose use is becoming more widespread day by day.
- Trial name
- NCT06098274
- Testing
- Motivational interviewing program based on transtheoretical model
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mustafa Yumusak
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Post-Traumatic Stress Disorder
Evaluation of a Yoga Intervention for Post-Traumatic Stress Disorder
The main objective of this preliminary randomized controlled clinical trial is to establish efficacy and feasibility of a yoga-based treatment for PTSD in military veterans as compared to a delayed yoga treatment (waitlist…
- Trial name
- EYIPTSD (NCT00962403)
- Testing
- Yoga treatment
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Insomnia
Playing Cognitive Games For Older Adults With Insomnia
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
- Trial name
- PLAY (NCT04282642)
- Testing
- Cognitive Training, WLC (Waitlist Control)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Vitamin D2 Supplementation in Vitamin D Insufficiency
Optimal Doses of Ergocalciferol Supplementation for Treatment of Hypovitaminosis D in Adults
To investigate the optimal initial and maintenance doses of vitamin D2 supplementation for the treatment of vitamin D insufficiency in Thai adults, and to determine the prevalence of and risk factors for hypovitaminosis D among…
- Trial name
- NCT03228862
- Testing
- Ergocalciferol
- Where
- Thailand
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Insomnia, ADHD
CBT-I in Adolescents With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by persistent patterns of inattention, hyperactivity, and impulsivity, affecting individuals across the lifespan.
- Trial name
- NCT07209969
- Testing
- CBT-I group
- Where
- 2 sites in Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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