Clinical trials: Major Depressive Diorder
Bipolar Disorder (BD), Major Depressive Diorder
Stress Management With Real-time Bio-signal Biofeedback
The goal of this clinical trial is to learn if the real-time bio-signal monitoring device (Neuronicle FX2 device), combined with mindfulness-based cognitive therapy (MBCT), helps manage stress and improves symptoms of mood…
- Trial name
- NCT06616116
- Testing
- Biosignal feedback
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Major Depressive Diorder
MAGNESIUM & SSRI VS SSRI ALONE AMONG PATIENTS OF MAJOR DEPRESSIVE DISORDER
Role of Magnesium in Depressive Disorder
- Trial name
- NCT07458022
- Testing
- Use of magnesium with SSRI, SSRI
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Major Depressive Diorder
RCT of Psilocybin-assisted CBT for Depression
The primary objectives of this clinical investigation are to (1) determine the acceptability and feasibility of joining psilocybin-assisted therapy with cognitive-behavioral therapy (PA-CBT) for patients with depression, (2)…
- Trial name
- NCT07281352
- Testing
- Psilocybin (drug), cognitive behavioral therapy, Minimal supportive therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Major Depressive Diorder, Early Life Trauma
Neurocircuitry Mechanisms and Efficacy of Lumateperone as Adjunctive Therapy for Major Depressive Disorder and History of Early Life Abuse
The purpose of this clinical research study is to understand how effective and safe an investigational study drug called lumateperone is and whether it works to reduce the severity of depressive symptoms in adults with Major…
- Trial name
- ITI-ELA-MDD (NCT07369115)
- Testing
- Lumateperone 42 mg
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas at Austin
Major Depressive Diorder, Low Self-Esteem
Imagery Rescripting in Primary Care
In the current study we aim to investigate the feasibility, acceptability, and effectiveness of ImRs offered by mental health assistants within primary care to reduce depressive symptoms.
- Conditions
- Major Depressive Diorder, Low Self-Esteem, Mood Disorders
- Trial name
- IMPACT MADE (NCT07362511)
- Testing
- Imagery Rescripting
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University of Amsterdam
Bipolar Disorder (BD), Schizophrenia Disorders
Creating a Global Research Database That Connects Genetic Information and Long-term Health Data to Improve Personalized Treatment for People With Serious Mental Illness
This observational study aims to provide new insights into the nature and classification of severe mental illness and dementias that in time should help improve diagnostic practise, and enable the development of new and improved…
- Conditions
- Bipolar Disorder (BD), Schizophrenia Disorders, Major Depressive Diorder, Dementia
- Trial name
- GlobalMinds (NCT06641726)
- Testing
- Not applicable- observational study
- Where
- United Kingdom
- Volunteers
- 50,000 people
- Sponsor
- Akrivia Health
Major Depressive Diorder
Efficacy and Safety of DTMS in Adolescent Major Depressive Disorder
The goal of this randomized controlled trial is to explore the efficacy and safety of two different dTMS devices in adolescent depression: deep TMS H1 coil and deep TMS H7 coil.
- Trial name
- NCT06728280
- Testing
- deep transcranial magnetic stimulation with H1coil, deep transcranial magnetic stimulation with H7 coil
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Zhifen Liu
Major Depressive Diorder
qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
This study aims to explore how repetitive transcranial magnetic stimulation (rTMS), a treatment for depression, affects brain function.
- Trial name
- NCT06719427
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Major Depressive Diorder
A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate Transcranial MR Guided Focused Ultrasound for Bilateral Anterior Capsulotomy in the Treatment of Medication-Refractory MDD
The purpose of this study is to evaluate the safety and initial effectiveness of MRI-guided focused ultrasound thermal ablation of a designated area in the brain of patients suffering from medication-refractory MDD, using the…
- Trial name
- NCT02348411
- Testing
- ExAblate
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Yonsei University