Clinical trials: Major Hepatectomy
Cancer, Liver Diseases
Perioperative Energy Expenditure in Major Liver Resection
Rationale: Complication rates after major liver resections remain as high as 43%. Many initiatives have been taken to reduce postoperative morbidity.
- Conditions
- Cancer, Liver Diseases, Liver Neoplasms
- Trial name
- PRO-NRG (NCT05931068)
- Testing
- Pre- and postoperative assessment
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Malignant Liver Disease, Major Liver Resection
Administration of Rifaximin to Improve Liver Regeneration and Outcome Following Major Liver Resection
Surgery is in almost all cases the only potentially curative treatment option for patients with primary or secondary malignancies of the liver.
- Trial name
- ARROW (NCT02555293)
- Testing
- XIFAXAN® (Rifaximin)
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- RWTH Aachen University
Colorectal Cancer
Cd133+ Cell Infusion in Patients With Colorectal Liver Metastases.
Treatment of patients with metastatic colorectal carcinoma is surgical resection. Only 10-15% of the patients will be candidates for curative resection. After response to chemotherapy this figure rises 10-13% more.
- Trial name
- cellcol (NCT03803241)
- Testing
- CD133+ infusion, portal vein embolization
- Where
- 2 sites in Spain
- Volunteers
- 4 people
- Sponsor
- Hospital San Carlos, Madrid
Liver Neoplasms, Liver Regeneration
Registry of Major Liver Resections Including ALPPS and Other Liver Resections in Two Stages
Recently a new method of induce similar hypertrophy in the liver as is observed after hepatectomy has been described and was given the eponym "ALLPS".
- Trial name
- ALPPSREG (NCT01924741)
- Testing
- ALPPS
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Zurich
Pancreaticoduodenectomy, Hepatectomy
Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy
With a major liver or pancreas operation, there is a chance that one will require a transfusion of blood products (either red blood cells or plasma). This may be necessary during the operation or a few days after surgery.
- Trial name
- NCT00200148
- Testing
- Normovolemic Hemodilution (ANH), Standard of care
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Liver Cancer, Liver Failure
Quantitative MRI and Outcomes of Liver Resection
The present observational study aims to assess the benefit of this quantitative multiparametric magnetic resonance imaging (MRI) in clinical practice, to quantify future liver remnant performance, and to accurately predict the…
- Conditions
- Liver Cancer, Liver Failure, Bile Leak, Liver Metastases
- Trial name
- NCT06181318
- Testing
- Multiparametric MRI scan of the liver
- Volunteers
- 33 people
- Sponsor
- University Hospital Heidelberg
Pancreaticoduodenectomy, Pancreatectomy
Intraoperative Cell Saver Autotransfusion Use for Major Surgical Oncology Operations.
The purpose of this study is to demonstrate the safety and benefit of auto-transfusion filtered blood in patients undergoing major surgical oncology procedures.
- Conditions
- Pancreaticoduodenectomy, Pancreatectomy, Esophagectomy, Gastrectomy
- Trial name
- Cellsaver (NCT00708513)
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of Louisville