Clinical trials: Major Surgical Resection of a Thoracic Malignancy
Lung Cancer, Perioperative/Postoperative Complications
Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer
RATIONALE: Exercise may help improve lung function and lessen complications of surgery in patients with chronic obstructive pulmonary disease who are undergoing surgery for lung cancer.
- Conditions
- Lung Cancer, Perioperative/Postoperative Complications, Pulmonary Complications, Tobacco Use Disorder
- Trial name
- NCT00363428
- Testing
- exercise intervention, smoking cessation intervention, counseling intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Malignant Neoplasm of Abdomen, Surgery
TAP Versus Thoracic Epidural in Major Abdominal Resections
The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block.
- Trial name
- NCT02197988
- Testing
- Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health West
Venous Thrombosis, Pulmonary Embolism
Extended Out-of-hospital Low-molecular-weight Heparin Prophylaxis Against DVT and PE in Patients Undergoing Major Lung Resection
Postoperative venous thromboembolism (VTE) is a significant health-care problem, resulting in significant morbidity, mortality and resource utilization. The true incidence is unknown, and may range from 1% to 15%.
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Lung Neoplasms
- Trial name
- NCT02258958
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- McMaster University
Older Adults, Anxiety
Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Inadequate management of preoperative mental health disorders often contributes to poor postoperative outcomes, including increased rates of readmission, delirium, falls, and mortality.
- Conditions
- Older Adults, Anxiety, Depression, Cardiac Surgery
- Trial name
- NCT05110690
- Testing
- Behavioral Activation, Medication Optimization
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Older Adults, Anxiety
Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery
Using a Hybrid Type 1 Effectiveness-Implementation randomized control trial (RCT) design, the investigators will test the effectiveness of a bundled behavioral activation and medication optimization in reducing symptoms of…
- Conditions
- Older Adults, Anxiety, Depression, Major Surgical Resection of a Thoracic Malignancy
- Trial name
- NCT05685511
- Testing
- Behavioral Activation, Medication Optimization, Usual care resources
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Robotic Surgical Procedure, Thymoma
A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal Disease
Endpoints (Outcome measures)： 1. Primary endpoint: Incidence of conversion rate during surgery The primary performance endpoint will be assessed as the ability to successfully complete the planned mediastinal procedure with da…
- Conditions
- Robotic Surgical Procedure, Thymoma, Myasthenia Gravis
- Trial name
- NCT05455840
- Testing
- Da Vinci SP surgical platform
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Chang Gung Memorial Hospital
Circulating Tumor Cell, Lung Cancer
Sequence of Vessel Interruption and Circulating Tumor Cells in Surgical Lung Cancer
This study aims to define the impact of the sequence of vessel interruption on change in CTC and CTC clusters density in the tumor-draining pulmonary vein between the period before surgical manipulation and before tumor-draining…
- Conditions
- Circulating Tumor Cell, Lung Cancer, Surgery
- Trial name
- CTC-01 (NCT03645252)
- Testing
- Vein interruption before any other surgical manipulation, Arteries interruption before vein interruption
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Venous Thromboembolism, Thoracic Surgery
Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection
The purpose of this study is to determine the incidence of post-operative venous thromboembolism (VTE) in patients undergoing major esophageal resection for malignancy.
- Conditions
- Venous Thromboembolism, Thoracic Surgery, Esophageal Cancer
- Trial name
- NCT03115541
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 187 people
- Sponsor
- McMaster University