Clinical trials: Malabsorption
Bileacid Malabsorption
Bileacid Malabsorption and GLP-1 Secretion
The aim of this study is to examine the influence of BAM on postprandial GLP--1 secretion and glucose homeostasis, both with and without bile acid sequestration.
- Trial name
- NCT03009916
- Testing
- "cholestagel®" (Colesevelam)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 1 Diabetes, Celiac Disease
Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)
The purpose of this study is to identify people with T1D or celiac disease (CD) early in the course of their disease and to improve the methods of screening for these diseases.
- Trial name
- ACCESS-T1D (NCT06908057)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Celiac Disease, Ultrasound
Small Bowel Ultrasound and Antibody Levels in Celiac Disease Activity
This observational study aims to evaluate the relationship between small bowel ultrasound findings and tissue transglutaminase (tTG) antibody blood levels in assessing celiac disease activity.
- Conditions
- Celiac Disease, Ultrasound, Tissue Transglutaminase Antibody, Small Bowel Ultrasonography
- Trial name
- NCT07453589
- Testing
- Small bowel ultrasonography, Serological testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Micronutrient Deficiencies, Hyperhomocysteinemia
Effectiveness of a Micronutrient Supplement to Lower Plasma Homocysteine MDEG2 Pilot Supplementation Trial
This micronutrient supplementation study is a 3-arm randomized controlled trial, unblinded, with 125 women per arm. Non-pregnant, non-lactating healthy women of reproductive age in West Kiang, The Gambia, will be randomized to 12…
- Trial name
- MDEG2-PST (NCT03431597)
- Testing
- novel micronutrient, existing micronutrient supplement, UNIMMAP
- Where
- The Gambia
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Probiotics
Use of a Selected Mixture of Probiotic Strains for Degrading Gluten During Digestion
Gluten intake spreads worldwide, being the major food protein consumed in the Western diets (up to 20 g gluten/d). But gluten has unique and unusual features.
- Trial name
- NCT05798689
- Testing
- Probiotic administration and gluten
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Free University of Bozen-Bolzano
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.
Irritable Bowel Syndrome, Crohn Disease
Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis
The SIMBA Capsule is a small, single-use, ingestible capsule that allows for the non-invasive sampling of small bowel contents using purely mechanical means.
- Conditions
- Irritable Bowel Syndrome, Crohn Disease, Celiac Disease, Ulcerative Colitis
- Trial name
- NCT05633706
- Testing
- fluid biopsy capsule
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nimble Science Ltd.
Celiac Disease
Mass Screening for the Early Detection of Patients With Celiac Disease.
The use of a home rapid test for the detection of both gluten immunogenic peptides (GIP) in urine and immunoglobulin A (IgA) anti tissue transglutaminase (anti-tTG) antibodies in blood may contribute to the early detection of…
- Trial name
- NCT05186038
- Testing
- iVYCHECK GIP Urine, CeliacDetect
- Where
- 2 sites in Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Biomedal S.L.
Intestinal Disease, Inflammatory Bowel Diseases
Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System
To validate an updated version of CapsoCam® SV-3 Endoscopy System brand name CapsoCam Plus™) with respect to the reproducibility of the system to capture and download small bowel images in a manner consistent with the predicate…
- Conditions
- Intestinal Disease, Inflammatory Bowel Diseases, Crohn Disease, Ulcer
- Trial name
- NCT04573959
- Testing
- SV-3 Capsule Endoscopy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Capso Vision, Inc.
Celiac Disease
Glutenfree, Gut Microbiota and Metabolic Regulation
High intake of dietary fiber provides health benefits and reduces the risk of developing cardio-metabolic diseases, such as type 2 diabetes (T2D) and cardiovascular disease (CVD).
- Trial name
- GRAIN (NCT05135923)
- Testing
- Randomized, controlled trial (RCT) with parallel arms and double blinded
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Catheter Related Infections, Short Bowel Syndrome
Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome
This study is designed to determine if the use of 70% ethanol lock solution in central lines decreases the rate of central line infections in children with short bowel syndrome.
- Trial name
- NCT01263574
- Testing
- 70% ethanol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Gluten Sensitivity
Influence of the Immunosystem in Non-celiac Glutensensitivity
Patients with non-celiac gluten sensitivity (NCGS) complain about gastrointestinal and extraintestinal symptoms while consuming gluten-containing cereals.
- Trial name
- NCGS (NCT03268720)
- Testing
- FODMAP low diet, gluten-free diet
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Vitamin D Deficiency, Fat Malabsorption
25-Hydroxyvitamin D Pharmacokinetic Study
To evaluate the pharmacokinetic parameters of orally administered 25-hydroxyvitamin D3 [25(OH)D3] and vitamin D3 from the corresponding serum concentration-time curves in healthy adults and adults with a history of intestinal…
- Trial name
- NCT03401541
- Testing
- Calcifediol, Calciferol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Short Bowel Syndrome, Intestinal Failure
Infant & Toddler Short Gut Feeding Outcomes Study
The purpose of this study is to better understand why children with short gut develop feeding problems.
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Home Parenteral Nutrition
- Trial name
- NCT01946503
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Lactose Intolerance
Evaluation of GIMate Handheld Hydrogen Breath Monitor for Diagnosis of Lactose Malabsorption
The goal of this study is to assess the performance of the Vivante Health GIMate Breathalyzer device in diagnosing lactose malabsorption.
- Trial name
- NCT04754724
- Testing
- GIMate, H2 Check
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vivante Health
Lactose Intolerance
Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.
The purpose of this study is to study the role of the enzyme (substance produced by the body that helps in a biochemical reaction like digestion in the body) responsible for digestion of lactose and the role of the gut bacteria…
- Trial name
- NCT03860051
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Indiana University
Short Bowel Syndrome
Plasma Determination of Glucagon-like Peptide 2 as a Predictor of Recovery in Adults With Acute Intestinal Failure
The purpose of this study is to investigate the theory that the plasma level of Glucagon like peptide 2 (GLP-2) in patients with intestinal failure can predict their clinical recovery.
- Trial name
- NCT00180648
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London