Clinical trials: Malalignment, Bone
Epiphysiodesis, Bone Malalignment
Plate vs. Screw for Guided Growth in Coronal Knee Deformities
The goal of this clinical trial is to compare two surgical techniques, Tension Band Plate (TBP) and Percutaneous Epiphysiodesis by Transphyseal Screw (PETS), in children with coronal angular knee deformities.
- Conditions
- Epiphysiodesis, Bone Malalignment, Lower Extremity Deformities, Congenital, Genu Varum
- Trial name
- PETS vs TBP (NCT06879015)
- Testing
- Tension Band Plate (TBP) Surgery, Percutaneous Epiphysiodesis by Transphyseal Screw (PETS) Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Osteoarthritis, Varus Malalignment
Computerized Tomography (CT) Scan Study of Bone Healing Following Open Wedge Proximal Tibial Osteotomy
The purpose of this study is to assess whether there is a difference between the TomoFix and Ellipse Intramedullary HTO Nail System in terms of bone regeneration in the tibial wedge by performing a CT-scan at 3 and 6-months…
- Trial name
- CISKO (NCT03431662)
- Testing
- Ellipse IM HTO Nail, TomoFix
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Ellipse Technologies, Inc.
Malalignment, Bone, Osteoarthritis, Knee
Knee Osteotomy Associated With Allograft Meniscus Transplantation
This is a prospective randomized double-blind controlled clinical trial with parallel arms and 1:1 allocation. The main objective of the BIOMAT project is to demonstrate, through an RCT, whether the combined approach by knee…
- Trial name
- NCT05840887
- Testing
- Knee osteotomy associated with meniscal allograft transplantation, Knee osteotomy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Osteoarthritis, Malalignment, Bone
Clinical and Radiological Results of Long Term Tibial and Femoral Osteotomy in Knee Ostheoarthritis With Concomitant Lower Limb Malalignement
The present study aims to evaluate the long-term and medium-term outcomes of different knee osteotomy techniques in the treatment of knee osteoarthritis in patients with lower limb malalignment.
- Trial name
- KNEE OSTEOTOMY (NCT06462625)
- Testing
- High tibial osteotomy
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteotomy, Malalignment, Bone
Comparison Between TOMOFIX and BodyCAD Fine Osteotomy
This is a single centre, randomised, patient blinded pilot study that will assign 40 participants with medial knee osteoarthritis undergoing medial opening wedge high tibial osteotomy (MOWHTO) to either current standard of care…
- Conditions
- Osteotomy, Malalignment, Bone, Osteoarthritis, Knee
- Trial name
- NCT06250530
- Testing
- High tibial osteotomy using TOMOFIX, High tibial osteotomy using BodyCAD
- Volunteers
- 40 people
- Sponsor
- Western University, Canada
Tibial Fractures, Surgery
Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.
Tibia shaft fractures are common long bone fractures in the field of Orthopaedic Trauma. In the USA, a total of 492.000 tibial fractures were reported per year by the National Center of Health Statistics (NCHS).
- Conditions
- Tibial Fractures, Surgery, Complication,Postoperative
- Trial name
- NCT05459038
- Testing
- C-Arm Rotational View (CARV)
- Where
- 2 sites in Australia, Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Bone Malalignment
CT Imaging Study for Knee Osteotomy (CISKO)
Malalignment of the knee joint causes arthritis in later life. Currently there are three surgical ways to treat knee arthritis: total knee replacement, partial knee replacement, and high tibial osteotomy (HTO).
- Trial name
- CISKO (NCT02717845)
- Testing
- Ellipse, Tomofix
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- North Cumbria University Hospitals NHS Trust
Camptodactyly, Arthropathy
CACP: Study on Camptodactyly - Arthropathy - Coxa Vara - Pericarditis (CACP) Syndrome
CACP syndrome is a rare autosomal recessive disorder characterized by the triad of camptodactyly, non-inflammatory arthropathy with synovial hyperplasia, and coxa vara.
- Conditions
- Camptodactyly, Arthropathy, Coxa Vara, Pericarditis
- Trial name
- CACP (NCT07468461)
- Where
- 10 sites in Italy, Spain and 1 more
- Volunteers
- 15 people
- Sponsor
- Meyer Children's Hospital IRCCS
Slipped Capital Femoral Epiphysis
Management of Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur Case Report.
Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur managed by subtrochanteric valgus osteotomy
- Trial name
- SCFE (NCT05758051)
- Testing
- subtrochanteric valgus osteotomy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Coxa Vara
Single-stage Correction of Acute Angle Coxa Vara
Correction of sever degree of coxa vara in single-stage correction.
- Trial name
- Coxavara (NCT05842252)
- Testing
- greater trochanter transfer, subtrochanteric valgus osteotomy
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Assiut University
Joint Disease, Joint Instability
Customized Biomechanical Models of the Musculoskeletal System Before and After Surgery
The objective of this study is to design a library of biomechanical musculoskeletal models of patients before and after surgery.
- Conditions
- Joint Disease, Joint Instability, Osteoarthritis, Bone Malalignment
- Trial name
- ORTHOSIMV1 (NCT03835000)
- Testing
- Orthopedic surgery
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Knee Osteoarthritis, Cartilage Degeneration
Impact of High Tibial Osteotomy in Preventing Degenerative Disease Progression in Medial Knee Osteoarthritis.
High tibial osteotomy (HTO) surgical procedure can lead to clinically significant improvements in the cartilage and in subchondral bone quality, with a slow down of the osteoarthritis (OA) progression.
- Conditions
- Knee Osteoarthritis, Cartilage Degeneration, Malalignment, Bone
- Trial name
- HTO-IOR (NCT05865899)
- Testing
- valgus producing medial opening wedge high tibial osteotomy
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Degenerative Lumbar Disease, Scoliosis
Priority-Matching Correction Technique in Degenerative Lumbar Scoliosis
Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with degenerative lumbar scoliosis (DLS) who underwent correction…
- Conditions
- Degenerative Lumbar Disease, Scoliosis, Degenerative Scoliosis
- Trial name
- PMCTDLS (NCT06470165)
- Testing
- Priority-matching correction technique in DLS, Traditional correction technique in DLS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Intestinal Failure, Osteoporosis
Effect of Nocturnal Parenteral Nutrition on Bone Turnover and Energy Metabolism
This clinical trial will study the effect of daytime versus nighttime parenteral nutrition on bone turnover, glucose variability, nitrogen balance, sleep and wake rhythm and peripheral clock gene expression in patients with…
- Conditions
- Intestinal Failure, Osteoporosis, Insulin Sensitivity
- Trial name
- NutriSync (NCT05868785)
- Testing
- Parenteral nutrition
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)