Clinical trials: Male Sexual Dysfunction
Erectile Dysfunction, Vascular Disease Detected
Simvastatin for Treating Erectile Dysfunction
This is a randomized clinical trial, double-blind, placebo controlled, to verify if simvastatin can improve erectile dysfunction in men with endothelial dysfunction, without any cardiac disease.It is hypothesized that the…
- Conditions
- Erectile Dysfunction, Vascular Disease Detected, C Reactive Protein
- Trial name
- STED (NCT00947323)
- Testing
- Simvastatin
- Volunteers
- 41 people
- Sponsor
- Santa Casa de Porto Alegre
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Low Libido
Hypoactive Sexual Desire Disorder in Males
The purpose of this study is to determine if the study drug will increase sexual desire in men with HSDD. Half of the participants will take ADDYI while the other half will receive a placebo (a look-alike pill with no medicine).
- Trial name
- HSDD (NCT04002661)
- Testing
- Flibanserin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mohit Khera
Erectile Dysfunction, Stem Cells
Intracavernous Injection of Autologous Mesenchymal Stem Cells in the Treatment of Erectile Dysfunction Resistant to Oral Treatment in Patients With Type I Diabetes
Diabetes is a major concern in public health because of its high frequency and its negative consequences. Erectile dysfunction (ED) is present, regardless of age, in 50 to 75% of men with diabetes.
- Conditions
- Erectile Dysfunction, Stem Cells, Diabetes Mellitus, Type 1
- Trial name
- MESERIC (NCT03361631)
- Testing
- Autologous Bone Marrow derived Mesenchymal Stem Cells
- Volunteers
- 13 people
- Sponsor
- Central Hospital, Nancy, France
Type 1 Diabetes, Polycystic Ovary Syndrome
Prevalence of Hyperandrogenism in Type 1 Diabetes
The investigators aim to estimate the prevalence of functional ovarian hyperandrogenism [idiopathic hyperandrogenism, idiopatic hirsutism, and polycystic ovary syndrome (PCOS)] in adult patients with type 1 diabetes (T1DM) in an…
- Conditions
- Type 1 Diabetes, Polycystic Ovary Syndrome, Hyperandrogenism, Hirsutism
- Trial name
- NCT04979377
- Testing
- Clinical hyperandrogenism assessment, Total testosterone (ng/dL), A1c (%)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Penile Cancer, Erectile Dysfunction
Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
When a bilateral nerve-sparing radical prostatectomy (RP) is performed, recovery of erectile function (rigid erections) is reported for up to 80% of patients, who are less than 60 years old.
- Conditions
- Penile Cancer, Erectile Dysfunction, Radical Prostatectomy
- Trial name
- NCT00955929
- Testing
- Sildenafil and questionnaire, Trimix combination (Papavarine 30mg/mL Phentholamine 1mg/mL Prostaglandin E1 10 mcg/mmL) and questionnaires
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Sexual Dysfunction
Sexual Quality of Patients After Bladder Cancer Cystectomy
Bladder cancer is the second most prevalent urological cancer in France. About 1 in 5 new cases of bladder cancer infiltrate the muscles.
- Trial name
- QSCO (NCT04964895)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Anterior Ischemic Optic Neuropathy
PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The primary objective of this study is to determine whether the use of PDE5 inhibitors (vardenafil, sildenafil, or tadalafil) increases the risk for the development of NAION.
- Trial name
- NCT00867815
- Testing
- Diagnostic procedures
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Bayer
Erectile Dysfunction
A Relative Bioavailability Study Between Two Formulations Of Sildenafil Citrate
The purpose of this study is to perform a relative bioavailability study between two formulations of sildenafil citrate.
- Trial name
- A1481272 (NCT00904748)
- Testing
- sildenafil citrate 100 mg CT, Viagra®
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Combination Therapy of Tadalafil 2.5mg Plus Sildenafil 25mg Versus Tadalafil 5 mg Monotherapy for Treatment of Erectile Dysfunction: A Randomized, Placebo-Controlled Double-Blinded Cross-Over Study
Erectile dysfunction (ED) is characterized by the persistent inability to attain or sustain an erection adequate for satisfactory sexual intercourse.
- Trial name
- NCT07177326
- Testing
- Tadalafil 2.5 mg, Sildenafil 25 mg, Tadalafil 5 mg
- Volunteers
- 142 people
- Sponsor
- Assiut University
Stress Urinary Incontinence, Sexual Dysfunction
Safety, Efficacy and Usage Compliance of the Silk'n Tightra Device
This is an open label, prospective study aimed to evaluate safety and efficacy of the Silk'n Tightra device for improvement of sexual functioning, vulvovaginal appearance and reduction of SUI.
- Conditions
- Stress Urinary Incontinence, Sexual Dysfunction, Vulvovaginal Atrophy
- Trial name
- NCT03900143
- Testing
- Tightra vaginal device
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Erectile Dysfunction
Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction
The purpose of this research study is to evaluate whether the combination of Shock Wave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and…
- Trial name
- COCKTAIL (NCT05048667)
- Testing
- Shock Wave therapy (SWT), Platelet Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Miami
Diabetes, Erectile Dysfunction
The Prevalence of Erectile Dysfunction (ED) and ED Related Quality of Life of Diabetic Men
Adult diabetic patients aged above 20 attending the diabetic clinic of National Taiwan University Hospital are invited to attend a face to face screening and interview.
- Trial name
- NCT00173134
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Hydrocelectomy, Erectile Dysfunction
Assessment of Sexual Function in Male Patients Undergoing Hydrocelectomy and Their Partners
This study aimed to assess changes in sexual function in men undergoing hydrocelectomy and their partners. Male patients who underwent hydrocelectomy in our clinic between 2020 and 2024 were included in the study This study was…
- Conditions
- Hydrocelectomy, Erectile Dysfunction, Sexual Dysfunction Male, Sexual Dysfunction Female
- Trial name
- NCT07069985
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Type 2 Diabetic Patients, Erectile Dysfunction
Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression…
- Trial name
- NCT01049750
- Testing
- type 2 diabetic patients
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- University of Pavia
Hypertension, Erectile Dysfunction
Does Erectile Dysfonction Allow to Evaluate Subendocardial Viability Among Treated Patients With Hypertension ?
Erectile dysfunction (ED) is associated with subclinical atherosclerosis and may precede clinically apparent coronary artery disease by two to five years.
- Trial name
- DEVISE (NCT07719790)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erectile Dysfunction
Treatment of Erectile Dysfunction I
Randomized, placebo-controlled, double-blind, parallel design, Phase 3 study to evaluate the safety and efficacy of udenafil, an orally administered, potent and selective inhibitor of PDE-5 versus placebo for the treatment of…
- Trial name
- NCT01037244
- Testing
- Udenafil
- Where
- 36 sites in United States
- Volunteers
- 618 people
- Sponsor
- Warner Chilcott
Erectile Dysfunction, Overactive Bladder
Mirabegron For Erectile Dysfunction
The only class of oral erectile dysfunction (ED) medication on the market are the phosphodiesterase Type 5 inhibitors (PDE5i). This pilot study is being done to evaluate the effect of Mirabegron, an oral beta-3 adrenergic…
- Conditions
- Erectile Dysfunction, Overactive Bladder, Urinary Incontinence
- Trial name
- NCT02916693
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Erectile Dysfunction
Mindfulness-Based-Cognitive-Intervention for African Caribbean Men With Erectile Dysfunction
Title of research: A preliminary Randomised Controlled Study online Mindfulness-Based-Intervention for African-Caribbean men with Erectile Dysfunction Research aim: How an online mindfulness intervention, based on a behavioral…
- Trial name
- NCT05167955
- Testing
- Mindfulness based cognitive intervention based on the behavioural change techniques taxonomy
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- London Metropolitan University
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