Clinical trials: Male Sexual Dysfunction
Erectile Dysfunction
Low Intensity Extracorporeal Shock Wave Therapy (Li-ESWT) for Erectile Dysfunction
Low-intensity extracorporeal shock wave therapy (Li-ESWT) has shown promise as a novel treatment for erectile dysfunction (ED), though the the mechanism of action and optimal protocol for administration has not been…
- Trial name
- NCT04720755
- Testing
- Low-Intensity Extracorporeal Shock Wave Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Erectile Dysfunction, Erectile Dysfunction Due to Venous Disorder
Shaeer's Vein Ligation-II: Internal Pudendal Vein Perineal Ligation For Veno Occlusive Erectile Dysfunction
The goal of this interventional study is to evaluate a new surgical technique (Shaeer's Perineal Internal Pudendal Vein Ligation (SHAEER-II)) in patients with deep system veno-occlusive erectile dysfunction (VOD) .
- Trial name
- Shaeer-II (NCT06121674)
- Testing
- Shaeer-II, PPI
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Healthy Male Volunteers
A Phase I Study to Investigate KH-001 in Healthy Males
This was a Phase I, first-in-human study of KH-001 besylate in healthy male participants, conducted to investigate the safety, tolerability and pharmacokinetics (PK) of the study drug.
- Trial name
- NCT07868237
- Testing
- KH-001 besylate
- Where
- United Kingdom
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kadence Bio
Erectile Dysfunction Due to General Medical Condition, Erectile Dysfunction Following Radical Prostatectomy
Platelet Rich Plasma (PRP) as Terapeutical Option in Erectil Disfunction (DE)
Patients are randomized into 2 groups (A and B), subsequently group A is subjected to a cycle of 6 weekly injections of 3 ml of autologous PRP while group B is subjected to 6 weekly injections of 1 ml of caverject (alprostadil)…
- Conditions
- Erectile Dysfunction Due to General Medical Condition, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunctions
- Trial name
- NCT06768177
- Testing
- PRP injection, Alprostadil 20 micrograms
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Erectile Dysfunction
Low-Intensity Extracorporeal Shock Wave Treatment for Erectile Dysfunction: A Randomized, Controlled, Double Blind Trial
The proposed mechanism of action for LI-ESWT in ED is that it improves endothelial function and triggers angiogenesis through induction of local growth factors and endothelial nitric oxide synthase.
- Trial name
- NCT03006536
- Testing
- Li-ESWT
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Endometriosis, Surgery
Symptoms and Quality of Life of Patients With Suspected Endometriosis
All patients undergoing surgery due to suspected endometriosis in a previously selected 3-month period within the study period (between 12/2022 and 12/24) (each participating center will define the particular 3 months in…
- Conditions
- Endometriosis, Surgery, Pain, Dysmenorrhea
- Trial name
- NCT05624567
- Volunteers
- 800 people
- Sponsor
- Medical University of Vienna
Male Hypogonadism, Sexual Dysfunction
D-chiroinositol Administration in Hypogonadal Males
D-chiroinositol (DCI), is known as second messenger of insulin pathway, but recently several works have reported the influence of DCI on steroidogenesis.
- Trial name
- NCT04708249
- Testing
- D-chiroinositol
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Lo.Li.Pharma s.r.l
Erectile Dysfunctions
Sham-Controlled Prospective Study Characterizing Erectile Tissue Ultrasound Changes Resulting From Penile LiSWT
The primary goal of this single blind, prospective sham-controlled clinical trial is to assess safety and efficacy of low intensity shockwave therapy (LiSWT) to improve erectile function in men 21-80 years of age with erectile…
- Trial name
- NCT06600893
- Testing
- Low intensity shockwave therapy (LiSWT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- San Diego Sexual Medicine
Erectile Dysfunction
Effectiveness And Safety Of Two Protocols For The Treatment Of Erectile Dysfunction With Low-Density Shock Waves
Randomized, experimental, non-inferiority clinical trial to determine the comparative effectiveness and safety of two protocols used in the treatment of Erectile Dysfunction (ED) with Low-Density Shock Waves (Li-ESWT), for…
- Trial name
- NCT02683044
- Testing
- Low-Intensity Extracorporeal Shock Wave Therapy (Li-ESWT)
- Where
- Colombia
- Volunteers
- 206 people
- Sponsor
- Instituto para la Evaluación de la Calidad y Atención en Salud
Erectile Dysfunction
Radial Shockwave Therapy for Erectile Dysfunction
Objective: To evaluate the efficacy and safety of radial shock waves for the treatment of erectile dysfunction [ED]. Patients and methods: Randomized, double-blind clinical trial.
- Trial name
- NCT03596047
- Testing
- Radial wave therapy
- Where
- Colombia
- Volunteers
- 80 people
- Sponsor
- Boston Medical Group
Erectile Dysfunction
A Study in Erectile Dysfunction
The purpose of this study is to determine the day of onset of efficacy of tadalafil dosed once-a-day.
- Trial name
- NCT00833638
- Testing
- Tadalafil
- Where
- United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction, Diabetes Mellitus, Type 2
Effect of ESWT on ED in Type 2 Diabetics
Diabetes mellitus (DM) is known not only for its widespread prevalence, but also for its significant complications including cerebrovascular disease, coronary artery disease, renal failure, vision loss, and neuropathy.
- Trial name
- NCT04219462
- Testing
- active extracorporeal shock wave
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Erectile Dysfunction
Investigate the Responsiveness of the Erectile Quality Scale to Vardenafil Flexible Dose vs Placebo in Males With Erectile Dysfunction (ED)
This study was conducted to evaluate in adult men with erectile dysfunction (often called impotence), the effect of vardenafil HCl on the quality of their erections.
- Trial name
- NCT00665340
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 12 sites in United States
- Volunteers
- 219 people
- Sponsor
- Bayer
Male Erectile Dysfunction
Phase II Trial of SK3530 in Erectile Dysfunction
This study was designed to evaluate the efficacy and safety of the SK3530 tablet and to find the optimal dose and dosage schedule after oral administration to patients with erectile dysfunction.
- Trial name
- NCT00351065
- Testing
- SK3530
- Volunteers
- 120 people
- Sponsor
- SK Chemicals Co., Ltd.
Prostate Cancer, Incontinence
Validating the 'Sexual Minorities and Prostate Cancer Scale' to Gold Standard Questionnaires
A cohort study comparing the novel 'Sexual Minorities and Prostate Cancer Scale' (SMACS) to the gold standard questionnaires investigating erectile dysfunction (IIEF) and incontinence (ICIQLUTSqol and ICIQ-UI) following robotic…
- Conditions
- Prostate Cancer, Incontinence, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- SMACS (NCT05772598)
- Where
- United Kingdom
- Volunteers
- 305 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Premature Ejaculation
Precise Use of Lidocaine Cream to Treat Primary Premature Ejaculation
This study aimed to evaluate the efficacy and safety of applying 5% lidocaine cream to the sensitive area of the glans penis after its precise localization under the penile biological vibration threshold test for the treatment of…
- Trial name
- NCT05749614
- Testing
- Lidocaine cream
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Erectile Dysfunction
A Phase 1 Trial of LIB-01 in Healthy Participants.
The goal of this clinical trial is to learn about the safety, tolerability and pharmacokinetics of LIB-01 in healthy male participants.
- Trial name
- NCT06324006
- Testing
- LIB-01
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Dicot AB
NSCLC Stage IV, Sex Disorder
ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung Cancer
Although many phase III clinical trials evaluate the quality of life as a secondary endpoint, male sexuality remains a neglected topic in oncology research.
- Conditions
- NSCLC Stage IV, Sex Disorder, Hypogonadism, Male, Erectile Dysfunction
- Trial name
- EROS (NCT06532149)
- Testing
- Alectinib, Brigatinib, Lorlatinib 100 mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypogonadism, Erectile Dysfunction
The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction
The purpose of this study is to evaluate the response of a treatment with testosterone undecanoate and determine the levels of total and free testosterone in hypogonadal patients with erectile dysfunction.
- Trial name
- NCT00421460
- Testing
- Testosterone Undecanoate,1000mg
- Where
- 3 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease
Vascular Effects of Penil revascularızatıon
Purpose: The aim of this study is to measure the effects of penile revascularization surgery performed in vascular origin erectile dysfunction (ED) on penile vascular hemodynamic and to determine the importance of vascular…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Venous Disorder
- Trial name
- NCT06350019
- Testing
- Penile revascularızation
- Volunteers
- 35 people
- Sponsor
- Ankara Yildirim Beyazıt University
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