Clinical trials: Male Sexual Dysfunction
Spinal Cord Injuries, Male Sexual Dysfunction
Depressive Symptoms and Sexual Dysfunction in Traumatic Spinal Cord Injury
Aims: assess the relationship between sexual function and depressive symptoms in individuals with spinal cord injury.
- Trial name
- NCT02958904
- Testing
- using questionnaires
- Volunteers
- 44 people
- Sponsor
- Universidade Federal de Pernambuco
Premature Ejaculation
A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation
This is a safety and efficacy study of OnabotulinumtoxinA for the treatment of premature ejaculation (PE) in male participants.
- Trial name
- NCT01917006
- Testing
- OnabotulinumtoxinA, Normal Saline
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 59 people
- Sponsor
- Allergan
Premature Ejaculation, Anxiety
Development and Validation of an Anxiety Disorder Prediction Model for Premature Ejaculation Patients
Background: Premature ejaculation (PE) is a common sexual dysfunction that can significantly impact the quality of life and psychological well-being of affected individuals.
- Trial name
- NCT06677814
- Where
- 2 sites in China
- Volunteers
- 700 people
- Sponsor
- Xijing Hospital
Dyspareunia
Changes to Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Prasterone in Women With Dyspareunia
Open label study at a single research center. Subjects meeting inclusion and exclusion criteria will receive 6.5 mg prasterone vaginal inserts daily for twenty weeks.
- Trial name
- NCT03568604
- Testing
- Prasterone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- San Diego Sexual Medicine
Premature Ejaculation
Safety and Efficacy of Escitalopram in the Treatment of Premature Ejaculation
Escitalopram has been claimed to have the highest selectivity for the human serotonin transporter relative to the noradrenaline or dopamine transporters. This might be associated with greater clinical efficacy.
- Trial name
- NCT00656552
- Testing
- Escitalopram
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Chronic Pain After Childbirth - Caesarean Section Compared to Vaginal Delivery and the Impact of Pre-existing Pain
There is no doubt, that surgery is very often the beginning of a chronic pain disorder. C-section is a worldwide performed operation with increasing trend in the developed countries .This prospective cohort study evaluated the…
- Trial name
- NCT03216044
- Volunteers
- 355 people
- Sponsor
- University Hospital Tuebingen
Erectile Dysfunction
A Study of DA-8159 in Subjects With Erectile Dysfunction
The purpose of this study will be to evaluate the clinical efficacy and safety of DA-8159, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of subjects with erectile dysfunction…
- Trial name
- NCT00282607
- Testing
- DA-8159
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Dong-A PharmTech Co., Ltd.
Multidisciplinary Communication
Multimodal Rehabilitation Programme on Epigenetic Biomarkers, Quality of Life, Sexual Function and Muscle Strength in Women With Dyspareunia and Endometriosis.
This study aims to evaluate the impact of a multimodal rehabilitation programme on epigenetic biomarkers in blood, quality of life, sexual function and pelvic floor muscle strength and endurance in women with dyspareunia and…
- Trial name
- NCT06614465
- Testing
- Multimodal Rehabilitation
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Clínica INEBIR
Erectile Dysfunction, Pulmonary Arterial Hypertension
Study of the Pharmacokinetics and Safety of TPN171H Tablets in Subjects With Mild ,Moderate Hepatic Insufficiency and Normal Liver Function
The study aims to investigate and compare the effect of TPN171H on subjects with mild and moderate hepatic impairment compared to healthy subjects.
- Trial name
- NCT05185011
- Testing
- TPN171H
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Breastfeeding, Postpartum Sexual Dysfunction
Postpartum Vaginal Estrogen for Breastfeeding Patients
Sexual dysfunction is very common in the postpartum period and is more common in people who breastfeed or pump. This research study was designed to help determine whether postpartum patients who use vaginal estrogen cream while…
- Conditions
- Breastfeeding, Postpartum Sexual Dysfunction, Vaginal Atrophy
- Trial name
- NCT05457972
- Testing
- Estradiol, Vaginal Moisturizer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University Hospitals Cleveland Medical Center
Sexual Pain Disorders, Postmenopausal Symptoms
Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment
This study will evaluate the use of topical 5 or 10% sinecatechins, a botanical drug derived from green tea for the alleviation of sexual pain in the area around the vaginal opening (the vulvar vestibule), that is a main source…
- Conditions
- Sexual Pain Disorders, Postmenopausal Symptoms, Vulvovaginal Atrophy, Female Sexual Dysfunction
- Trial name
- NCT03682601
- Testing
- 5% sinecatechins ointment, 10% sinecatechins ointment
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GTO Pharmaceutical, LLC
Prostate Cancer, Sexual Dysfunction
High-Intensity Focused Ultrasound Focal Ablation in Treating Patients With Progressive Prostate Cancer
RATIONALE: High-intensity focused ultrasound focal ablation uses high-energy sound waves to kill tumor cells. PURPOSE: This phase II trial is studying the side effects of high-intensity focused ultrasound focal ablation and to…
- Trial name
- NCT00988130
- Testing
- laboratory biomarker analysis, questionnaire administration, assessment of therapy complications
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University College London Hospitals
Prostate Cancer, Erectile Dysfunction
SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)
Robotic-assisted radical prostatectomy (RALP) has become the standard of care in the management of localized prostate cancer. However, post-prostatectomy erectile dysfunction (ED) and urinary incontinence still pose a challenge…
- Trial name
- NCT06945315
- Testing
- RALP (Robotic-assisted radical prostatectomy), SAFE (Saline assisted fascial engorgement)
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Erectile Dysfunction
The Impact of Dietary Pattern on Erectile Function
The goal of this study is to determine whether erectile function is impacted by dietary patterns in healthy men with normal erectile function.
- Trial name
- ERECTION (NCT04349059)
- Testing
- Animal based diet, Plant based diet
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Sexual Dysfunction, Sexual Dysfunctions, Psychological
Mindfulness as Treatment of Sexological Problems
The primary aim of this study is to test Mindfulness in Sex Therapy and Intimate Relationships (MSIR) as an add-on treatment to sex therapy in a clinical sample of patients referred with sexual problems, controlling for time…
- Conditions
- Sexual Dysfunction, Sexual Dysfunctions, Psychological, Sexual Dysfunctions, Physiological
- Trial name
- NCT03775239
- Testing
- Mindfulness in Sex Therapy and Intimate Relationships (MSIR), Treatment-as-usual
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Impotence
Titration Study to Evaluate Efficacy and Satisfaction of Viagra in Men With Erectile Function.
To evaluate the efficacy of Viagra dose titration to 100mg versus 50mg in men with erectile dysfunction, based on responses to the IIEF questionnaire as measured at the beginning and at the end of double blind treatment…
- Trial name
- NCT00249730
- Testing
- Sildenafil
- Where
- 39 sites in Canada, France and 6 more
- Volunteers
- 510 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction, Testosterone Deficiency
Effect of Testosterone in Men With Erectile Dysfunction
The purpose of this placebo-controlled study is to determine if testosterone replacement therapy, administered by transdermal gel, can improve the response to sildenafil (Viagra R) treatment in men who have erectile dysfunction…
- Conditions
- Erectile Dysfunction, Testosterone Deficiency, Diabetes
- Trial name
- TED (NCT00512707)
- Testing
- Sildenafil citrate (open label), Testosterone gel
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Boston University
Chronic Myelocytic Leukemia, Erectile Dysfunctions
A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome, resulting in the constitutive activation of the BCR-ABL1 tyrosine kinase.
- Conditions
- Chronic Myelocytic Leukemia, Erectile Dysfunctions, CVD - Cardiovascular Disease, Tyrosine Kinase Inhibitor
- Trial name
- ED2024 (NCT07061145)
- Testing
- Tirosin Kinase Inhibitors
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Erectile Dysfunction
Effect of Repeating Low Intensity Extracorporeal Shock Wave Treatment (LI-ESWT) for Erectile Dysfunction (ED)
The present study evaluates the efficacy and safety of repetitive treatments of Low Intensity Extracorporeal Shock Wave Treatment (LI-ESWT) using Aries ED device in men with mild-moderate and severe vasculogenic ED, who have…
- Trial name
- NCT03089372
- Testing
- ARIES-ED device
- Where
- Greece
- Volunteers
- 36 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Gynecologic Disease, Adnexal Mass
Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach
Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a recent innovation in minimally invasive surgery which has already proven its non-inferiority to conventional abdominal laparoscopy (CAL) for hysterectomy…
- Conditions
- Gynecologic Disease, Adnexal Mass, Adnexal Cyst, Sexuality
- Trial name
- NCT05761275
- Testing
- Elective cystectomy, Elective oophorectomy, Elective salpingectomy
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- Jean Dubuisson
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