Clinical trials: Male Sexual Dysfunction
Erectile Dysfunctions
Safety And Efficacy Of L-Arginine Monotherapy Versus Tadalafil Monotherapy Versus Their Combination In Men With Erectile Dysfunction; A Prospective Randomized Study
Introduction Sexual dysfunctions are annoying health problems with the erectile problems forming the main part of them. Erectile dysfunction (ED) is defined as the persistent inability to obtain or maintain an erection that is…
- Trial name
- NCT06947265
- Testing
- L-Arginine, Tadalafil 5 mg
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Fayoum University Hospital
Hypogonadism, Male, Cancer
Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency
This is a large randomized, double-blind, placebo-controlled trial to determine the efficacy of testosterone replacement on cancer-related fatigue in older men with solid or hematologic (blood) cancer who report fatigue and have…
- Conditions
- Hypogonadism, Male, Cancer, Fatigue
- Trial name
- TEMEC (NCT04301765)
- Testing
- testosterone 1.62% gel
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Hypogonadism, Erectile Dysfunction
Efficacy and Safety Evaluating Fispemifene in the Treatment of Hypogonadal Men With Erectile Dysfunction Unresponsive to PDE5 Inhibitors
The objective of the study is to assess and compare the preliminary efficacy, safety and tolerability of fispemifene 300 mg and placebo given once daily for 8 weeks in the treatment of hypogonadal men with erectile dysfunction…
- Trial name
- NCT00415571
- Testing
- Fispemifene (once daily for 8 weeks)
- Where
- 14 sites in United States
- Volunteers
- 72 people
- Sponsor
- QuatRx Pharmaceuticals Company
Healthy Volunteers, Erectile Dysfunction
Phase I Study to Investigate the Alcohol Interaction of DA8159
This study is designed to to investigate the effects of alcohol on the pharmacokinetics of Udenafil tablet in healthy male volunteers
- Trial name
- DA8159_DIA_I (NCT01241032)
- Testing
- Udenafil, Alcohol
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Klinefelter Syndrome, Infertility, Male
Unraveling the Klinefelter's Disease Physiopathology
Organoid Model to unravel Klinefelter Syndrome infertility Klinefelter Syndrome (KS) is characterized by the presence of an extra chromosome X in male (47,XXY), it is the most frequent genetic cause of azoospermia in adult men.
- Trial name
- KLINEFELTER (NCT05997706)
- Testing
- Testicular biopsy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Vulvodynia, Dyspareunia
Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial
We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
- Conditions
- Vulvodynia, Dyspareunia, Lichen Sclerosus of Vulva
- Trial name
- NCT07260825
- Testing
- Estradiol 0.01% Vag Cream, testosterone 0.1% and estradiol 0.01% vaginal cream
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- TriHealth Inc.
Erectile Dysfunction, Impotentia Erigendi
External Device for Erectile Dysfunction (3D-Erect)
The aim of this clinical trial is to test the safety and feasibility of a non-invasive 3D-printed external penile device to achieve successful and satisfactory sexual intercourse in men with erectile dysfunction (ED).
- Trial name
- 3D-Erect (NCT04624126)
- Testing
- 3D-Erect
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Turner Syndrome, Post-menarcheal Adolescents
Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
Background: Turner Syndrome, galactosemia, and premature ovarian insufficiency are all conditions that may make it very hard or impossible for a person to become pregnant and have their own child.
- Conditions
- Turner Syndrome, Post-menarcheal Adolescents, Ovarian Disfunction, Galactosemia
- Trial name
- NCT04948658
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Peyronie's Disease
Assessment of the Value of FAPI and FDG-PET-CT in Diagnosis of Acute Phase Peyronie's Disease
The goal of this clinical trial is to learn if FAPI-PET/CT and/or FDG-PET/CT scan is able to detect active fibroblast tissue and inflammation in patients with acute or chronic phase PD.
- Trial name
- Hippocrates (NCT07903987)
- Testing
- 68Ga-FAPI (gallium-68-labeled fibroblast activation protein inhibitor)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Vaginal Atrophy, Sexual Dysfunction
Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause
This multi-center clinical trial will evaluate the safety and long-term efficacy of hybrid fractional 2940 nm and 1470 nm lasers for treatment of symptoms of Genitourinary Syndrome of Menopause.
- Conditions
- Vaginal Atrophy, Sexual Dysfunction, Dyspareunia, Vaginal Dryness
- Trial name
- NCT03178825
- Testing
- Hybrid Fractional Laser
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sciton
Premature Ejaculation
Proof of Mechanism in ELT
The purpose of this study is to determine if the administration of GSK958108 can delay ejaculation in patients with primary premature ejaculation as measured by the ejaculatory latency time (ELT) using the masturbation model and…
- Trial name
- PoM (NCT00861484)
- Testing
- GSK958108
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- GlaxoSmithKline
Erectile Dysfunction
Phase 2a Trial to Investigate the Efficacy of LIB-01 in Treatment of Erectile Dysfunction
The goal of this clinical trial is to learn if the drug LIB-01 works to treat erectile dysfunction in male adults. It will also learn about the safety of the drug LIB-01.
- Trial name
- NCT06703840
- Testing
- LIB-01
- Where
- 6 sites in Denmark, Netherlands and 1 more
- Volunteers
- 156 people
- Sponsor
- Dicot AB
Erectile Dysfunction, Erectile Dysfunction (ED)
Satisfaction of Patients With Erectile Dysfunction With the Use of Sildenafil Oral Suspension Compared to Orodispersible Tablets
The goal of this observational retrospective study is to to evaluate treatment satisfaction with sildenafil oral suspension in patients with mild-to-moderate ED who were previously taking orodispersible sildenafil.
- Trial name
- SILOROS (NCT07676617)
- Testing
- Sildenafil Oral Suspension Compared to Orodispersible Tablets
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Erectile Dysfunction
Clinical Evaluation of Effectiveness and Safety of Dietary Supplement Potensa in Men With Erectile Dysfunction
This is a randomized, double blind, placebo-controlled, comparative, prospective study (clinical evaluation) of the effectiveness and safety of dietary supplement Potensa in men with mild to moderate erectile dysfunction.
- Trial name
- NCT03039504
- Testing
- Potensa, a succinate-based dietary supplement
- Where
- 2 sites in Russia
- Volunteers
- 106 people
- Sponsor
- Research Center, LLC
Impotence, Depression
Efficacy Study Measuring The Impact Of Treatment With Viagra On The Depressive Symptoms Of Men With Erectile Dysfunction
This study will measure the impact of treatment with Viagra on the depressive symptoms and quality of life in men with erectile dysfunction who have untreated depressive symptoms meeting the DSM-IV criteria for dysthymia or…
- Trial name
- NCT00159809
- Testing
- Viagra (Sildenafil citrate)
- Volunteers
- 140 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Impotence
To Determine Effect and Safety of Tadalafil Taken by Men of Different Races and With Different Diseases When Needed for Erections
To compare men of different races and those with diabetes or depression to white men that do not have diabetes or depression but also suffer from the inability to get or keep an erection.
- Trial name
- NCT00547417
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 1,933 people
- Sponsor
- Eli Lilly and Company
Impotence
Determine Safety and Effectiveness of Tadalafil in Asian Men When Taken as Needed for Getting and Keeping an Erection
Study to determine if tadalafil works better than placebo for Asian men having trouble getting or keeping an erection.
- Trial name
- NCT00547573
- Testing
- tadalafil
- Where
- China
- Volunteers
- 367 people
- Sponsor
- Eli Lilly and Company
Interstitial Cystitis, Sexual Dysfunction
The Women's Urology Center/WISH Database Project
Comprehensive database from the Women's Urology Center/WISH (Women's Initiative for Pelvic Pain and Sexual Health) program at Beaumont.
- Conditions
- Interstitial Cystitis, Sexual Dysfunction, Pelvic Pain, Incontinence
- Trial name
- NCT00379002
- Where
- United States
- Volunteers
- 2,923 people
- Sponsor
- Corewell Health East
Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Rectal neoplasia is one of the most prevalent cancers in Spain, and the treatment of choice is total mesorectal excision (TME), as it has demonstrated significant oncological improvements.
- Conditions
- Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant, Quality of Life (QOL), Fecal Incontinence (FI)
- Trial name
- NCT07632196
- Testing
- Posterior tibial nerve stimulation intervention group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Spinal Cord Injuries, Neurogenic Bladder
Below the Belt: Non-invasive Neuromodulation to Treat Bladder, Bowel, and Sexual Dysfunction Following Spinal Cord Injury
Recent findings have demonstrated that electrical stimulation to the spinal cord (i.e. implanted electrodes) can significantly recover bladder, bowel, and sexual function after injury.
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder, Neurogenic Bowel, Spinal Cord Stimulation
- Trial name
- NCT04604951
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
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