Clinical trials: Male Sexual Dysfunction
Menopause, Vulvovaginal Atrophy
TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy
The study was designed to evaluate the efficacy and safety of TX-12-004-HR 10 μg in treating moderate to severe symptoms of vaginal atrophy associated with menopause after 14 days of treatment, and to estimate the effect size and…
- Conditions
- Menopause, Vulvovaginal Atrophy, Painful Intercourse, Dyspareunia
- Trial name
- NCT02449902
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- TherapeuticsMD
Erectile Dysfunction, Diabetes Mellitus Type 2
Umbilical Cord Mesenchymal Stem Cell Secretome Administration in Severe Erectile Dysfunction Non-responsive to Sildenafil
The study is an experimental pre-post-test design involving 12 patients with severe ED non-responsive to sildenafil. Safety parameters included pain, hematoma, local bleeding, and infection, while efficacy was measured using the…
- Trial name
- NCT07245875
- Testing
- Intracavernosal Injection of Umbilical Cord Mesenchymal Stem Cell Secretome
- Where
- Indonesia
- Volunteers
- 12 people
- Sponsor
- Universitas Indonesia
Erectile Dysfunction
Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction
Researchers are evaluating the efficacy of low intensity shockwave therapy (LISWT) via MoreNova in the treatment of erectile dysfunction (ED).
- Trial name
- NCT04136288
- Testing
- MoreNova
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Erectile Dysfunction, Hypertension
Trial to Evaluate the Efficacy and Safety of HCP1302
Trial to Evaluate the Efficacy and Safety of HCP1302
- Trial name
- NCT02587988
- Testing
- HCP1302, HGP0904
- Volunteers
- 232 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Erectile Dysfunction
Endovascular Therapy for Erectile Dysfunction
Brief Summary: Background and pathophysiology Erectile dysfunction is a serious disease with a significant impact on the quality of life.
- Trial name
- RE-ACTION (NCT04333173)
- Testing
- endovascular procedure
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Clinica San Gaudenzio
Erectile Dysfunction, Benign Prostatic Hyperplasia
Efficacy, Safety and Dose-response of Udenafil in Patients With Benign Prostatic Hyperplasia and Erectile Dysfunction
The purpose of this study is to evaluate the efficacy, dose-response and safety of udenafil 25 mg, 50 mg and 75 mg every day (q.d.) for 12 weeks in the treatment of lower urinary tract symptoms (LUTS) associated with benign…
- Trial name
- NCT01967251
- Testing
- Udenafil
- Where
- 8 sites in Mexico
- Sponsor
- Takeda
Erectile Dysfunction With Diabetes Mellitus
Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction
The goal of this prospective randomized controlled clinical study is to evaluate the effectiveness and safety of intracavernosal injections of umbilical cord-derived mesenchymal stem cells (MSCs) and umbilical cord-derived…
- Trial name
- NCT07480161
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cells, Umblical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Premature Ejaculation
Sildenafil Added Effect in Dapoxetine Non-responding Mono-symptomatic Premature Ejaculation (PE)
Study Design: Single Blind Placebo Controlled Randomized Trial, aiming to assess the efficacy and safety of adding sildinafile 50 mg to dapoxitine 30 mg in dapoxitine non responding premature ejaculation.
- Trial name
- PE (NCT05556083)
- Testing
- Sildenafil 50 mg Oral Tablet and Dapoxitine 3mg Oral tablet
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction, Tadalafil
Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile Dysfunction
This randomized trial will compare daily tadalafil 5 mg as adjunct therapy versus monotherapy in men with on-demand PDE5 inhibitor-resistant erectile dysfunction.
- Trial name
- NCT07753720
- Testing
- Tadalafil; Current on-demand PDE5 inhibitor, Tadalafil 5 mg
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction
BAY38-9456 (Vardenafil HCL Tablet) in ED Treatment for China Registration.
This study was to compare the efficacy of 3 doses of vardenafil, 5 mg, 10 mg and 20 mg, with matching placebo in Chinese male ED patients, treated for a maximum of 12 weeks.
- Trial name
- NCT00668057
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 7 sites in China
- Volunteers
- 624 people
- Sponsor
- Bayer
Erectile Dysfunction
Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment
Clinical effectiveness is of the finest tools to evaluate treatment success and is combined of 3 elements: treatment effectivity, side effect profile and patient compliance.
- Trial name
- PDE5i (NCT01364701)
- Testing
- Sildenafil 100 mg, Tadalafil 20 mg, Combination half of maximal dose for sildenafil & tadalafil
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Alcohol, Phosphodiesterase Inhibitor
A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects
The purpose of this study is primarily to evaluate the effects of taking TPN171H tablets with alcohol on blood pressure, pulse,and pharmacokinetic in Chinese healthy male subjects.
- Conditions
- Alcohol, Phosphodiesterase Inhibitor, Erectile Dysfunction
- Trial name
- NCT05316428
- Testing
- TPN171H tablet plus alcohol, alcohol, TPN171H tablet
- Where
- China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Premature Ejaculation, Sexual Function Disturbances
The Effect of Behavioral Therapy Given to Men and Their Partners'
Premature ejaculation involves not only sexual problems but also relationship and communication difficulties, and behavioral approaches to the treatment of premature ejaculation are promising.
- Trial name
- NCT05964608
- Testing
- Behavioral Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- University of Gaziantep
Spinal Cord Injuries
Treatment for Sexual Dysfunction in Women with Spinal Cord Injury
Women with spinal cord injury frequently experience sexual dysfunction such as disturbances during arousal and an increased time to orgasm. However, little evidence has been found on its therapeutic approach and low adherence.
- Trial name
- NCT05122325
- Testing
- Transcutaneous tibial nerve stimulation TENS® EMS NMS60 device, Genital vibration with Ferticare 2.0® vibrator
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Cristina Lirio
Premature Ejaculation, Stress
Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men
The current study focuses on clinical validation of efficacy of nutraceutical product in management of male health. In healthy adult men with induced premature ejaculation, the introduction of these nutraceuticals has been…
- Trial name
- NCT06571318
- Testing
- Destress and Perform Capsule-U001, Destress and Perform Capsule-I001
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herbolab India Pvt. Ltd.
Periodontitis, Erectile Dysfunction
The Effects of Non -Surgical Periodontal Treatment on The Severity of Erectile Dysfunction
The aim of the present study is to study the influence of periodontal therapy (non-surgical) on the severity of erectile dysfunction(ED) among patients with chronic periodontitis and moderate or severe ED.
- Trial name
- NCT04129814
- Testing
- Non surgical periodontal therapy
- Volunteers
- 140 people
- Sponsor
- Taibah University
Post Operative Recovery
Continence and Potency Following Multi-Layer Perinatal Issue alloGraft
The purpose of this research is to determine the effectiveness of using human Umbilical Cord (UC) allograft to help improve return to erectile function and bladder control in patients following robot-assisted radical…
- Trial name
- NCT05081232
- Testing
- MLG (Multi-Layered Perinatal Issue Allograft) Allograft
- Sponsor
- Wake Forest University Health Sciences
Erectile Dysfunction
Safety of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Erectile Dysfunction
This phase I clinical trial is designed to evaluate the safety of autologous Mesenchymal Stem Cells (MSC) injected intracavernously.
- Trial name
- NCT02344849
- Testing
- mesenchymal stem cell
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Pharmicell Co., Ltd.
Erectile Dysfunction
Efficacy and Safety Study of Udenafil to Treat Erectile Dysfunction
Study Design : multi-center, double-blind, placebo-controlled, randomized, parallel group, fixed dose design Phase : Phase III
- Trial name
- NCT01774864
- Testing
- DA-8159 (Udenafil)
- Volunteers
- 349 people
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Erectile Dysfunction
Efficacy of Intracavernosal Xeomin With Tadalafil for Mild-Moderate Erectile Dysfunction
Erectile dysfunction (ED) affects approximately 30 million men in the United States and is associated with factors such as aging, smoking, diabetes, hypertension, obesity, and sedentary lifestyle.
- Trial name
- NCT07537855
- Testing
- IncobotulinumtoxinA (100 Units), Tadalafil 20 MG
- Volunteers
- 30 people
- Sponsor
- Northwestern University
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