Clinical trials: Malignant Esophageal Strictures
Esophageal Cancer, Esophageal Stenosis
Fully Covered or Partially Covered Stents in Malignant Esophageal Strictures
The purpose of this study is to determine whether fully covered or partially covered metal stents are more favorable in incurable malignant stenosis of the esophagus or cardia.
- Trial name
- COPAC (NCT01661686)
- Testing
- Partially covered SEMS, Fully covered SEMS
- Where
- 5 sites in Netherlands
- Volunteers
- 98 people
- Sponsor
- Foundation for Liver Research
Malignant Esophageal Strictures
EndoMAXX Endoluminal Valve Technology (EVT) Compared to EndoMAXX
This is a prospective, single blinded, randomized study of EndoMAXX Endoluminal Valve Technology (EVT) Fully Covered Esophageal Stent with Valve for the treatment of malignant strictures of the lower esophagus.
- Trial name
- NCT02159898
- Testing
- EndoMAXX Endoluminal Valve Technology (EVT), EndoMAXX
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Merit Medical Systems, Inc.
Dysphagia
Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection
The purpose of this pilot study is to find out if adding triamcinolone (steroid) injection at the participant's initial esophagogastroduodenoscopy (EGD) procedure will improve the opening of their esophagus and decrease the need…
- Trial name
- NCT01873573
- Testing
- Dilation, Triamcinolone Injection, Esophagogastroduodenoscopy (EGD)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Esophageal Cancer
Balloon Dilation to Permit Complete Endoscopic Ultrasound Staging in Esophageal Cancer
Despite improvement in treatment-related morbidity and mortality, esophageal cancer is still one of the most lethal malignancies. Accurate staging is essential to establish prognosis and for patient management.
- Trial name
- CT0046 (NCT01950442)
- Testing
- Balloon dilation
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Oesophageal Cancer
Esophageal Self-expandable Metal Stent for Malignant Strictures: a Safety and Efficacy Study
A single center prospective observational non-randomized clinical study to assess the safety and efficacy of placement of a new esophageal self-expandable metal stent (SEMS) for palliation of patients with malignant dysphagia.
- Trial name
- ENTRANCE (NCT06364553)
- Testing
- Esophageal self-expandable metal stent
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Erasmus Medical Center
Esophageal Cancer, Cancer of Gastro Esophageal Junction
Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent.
Self expandable stent (SEMS) constitutes the main palliative treatment in advanced esophageal cancer. The palliative effect of SEMS is immediate when it comes to relief of dysphagia.
- Conditions
- Esophageal Cancer, Cancer of Gastro Esophageal Junction, Palliative Treatment
- Trial name
- StentMig (NCT02166320)
- Testing
- Partially covered SEMS, Fully covered SEMS
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Oesophageal Cancer, Esophageal Stent Stenosis
Esophageal Multisegmented FCSEMS for Malignant Strictures
Objective: To assess the safety and feasibility of the implementation of the esophageal multisegmented fully covered self-expandable metal stent (SEMS) for the palliation of patients with malignant dysphagia.
- Trial name
- EATERS (NCT04415463)
- Testing
- Multisegmented fully covered self-expandable metal stent
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Radboud University Medical Center